© 2016

Magnetic Resonance Spectroscopy of Degenerative Brain Diseases

  • Gülin Öz
  • A comprehensive overview of clinical and pre-clinical applications of MRS Suitable for scientists and clinicians

  • A guide to the unique information provided by biomarkers of neurodegeneration?


Part of the Contemporary Clinical Neuroscience book series (CCNE)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Bart W. J. Philips, Tom W. Scheenen
    Pages 31-54
  3. Jonathan Graff-Radford, Kejal Kantarci
    Pages 55-70
  4. Ulrike Dydak, David A. Edmondson, S. Elizabeth Zauber
    Pages 71-102
  5. Fanny Mochel, Janet M. Dubinsky, Pierre-Gilles Henry
    Pages 103-120
  6. Varan Govind
    Pages 121-150
  7. Niamh Cawley, Olga Ciccarelli
    Pages 151-177
  8. Pierre-Gilles Henry, H. Brent Clark, Gülin Öz
    Pages 179-200
  9. Jullie W. Pan
    Pages 241-259
  10. Back Matter
    Pages 261-268

About this book


The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field. MRS has proven to be a powerful complementary tool to MRI for the diagnosis and monitoring of disease progression and response to treatment because it can detect changes in cell density, cell type, and biochemical composition, not just structural changes. As the population in the developed world continues to age, neuroimaging for diagnosis, prognosis, and therapy monitoring of neurodegenerative diseases becomes increasingly important and there has been a recent surge of clinical and pre-clinical applications of MRS indicating that this technique can provide robust and non-invasive biomarkers of degeneration. ​


biomarkers diagnosis magnetic resonance spectroscopy neurochemicals neurodegenerative diseases treatment

Editors and affiliations

  • Gülin Öz
    • 1
  1. 1.University of Minnesota Medical SchoolCenter Magnetic Resonance Research University of Minnesota Medical SchoolMinneapolisUSA

Bibliographic information

  • Book Title Magnetic Resonance Spectroscopy of Degenerative Brain Diseases
  • Editors Gülin Öz
  • Series Title Contemporary Clinical Neuroscience
  • Series Abbreviated Title Contemporary Clinical Neuroscience
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-33553-7
  • Softcover ISBN 978-3-319-81545-9
  • eBook ISBN 978-3-319-33555-1
  • Edition Number 1
  • Number of Pages XV, 268
  • Number of Illustrations 23 b/w illustrations, 32 illustrations in colour
  • Topics Neurosciences
  • Buy this book on publisher's site
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