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  • Book
  • Open Access
  • © 2020

Good Research Practice in Non-Clinical Pharmacology and Biomedicine

  • First comprehensive book on factors associated with high risk for poor reproducibility of non-clinical findings

  • Inclusion of aspects of study design, data analysis and data reporting

  • Broad applicability to in vitro and in vivo research across all therapeutic areas

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 257)

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Softcover Book USD 54.99
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  • Dispatched in 3 to 5 business days
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Hardcover Book USD 59.99
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Table of contents (21 chapters)

  1. Front Matter

    Pages i-x
  2. Quality in Non-GxP Research Environment

    • Sandrine Bongiovanni, Robert Purdue, Oleg Kornienko, René Bernard
    Pages 1-17Open Access
  3. Guidelines and Initiatives for Good Research Practice

    • Patricia Kabitzke, Kristin M. Cheng, Bruce Altevogt
    Pages 19-34Open Access
  4. Learning from Principles of Evidence-Based Medicine to Optimize Nonclinical Research Practices

    • Isabel A. Lefevre, Rita J. Balice-Gordon
    Pages 35-54Open Access
  5. General Principles of Preclinical Study Design

    • Wenlong Huang, Nathalie Percie du Sert, Jan Vollert, Andrew S. C. Rice
    Pages 55-69Open Access
  6. Blinding and Randomization

    • Anton Bespalov, Karsten Wicke, Vincent Castagné
    Pages 81-100Open Access
  7. Quality of Research Tools

    • Dario Doller, Paul Wes
    Pages 119-145Open Access
  8. Genetic Background and Sex: Impact on Generalizability of Research Findings in Pharmacology Studies

    • Stacey J. Sukoff Rizzo, Stephanie McTighe, David L. McKinzie
    Pages 147-162Open Access
  9. Building Robustness into Translational Research

    • Betül R. Erdogan, Martin C. Michel
    Pages 163-175Open Access
  10. Minimum Information and Quality Standards for Conducting, Reporting, and Organizing In Vitro Research

    • Christoph H. Emmerich, Christopher M. Harris
    Pages 177-196Open Access
  11. Minimum Information in In Vivo Research

    • Patrizia Voehringer, Janet R. Nicholson
    Pages 197-222Open Access
  12. A Reckless Guide to P-values

    • Michael J. Lew
    Pages 223-256Open Access
  13. Electronic Lab Notebooks and Experimental Design Assistants

    • Björn Gerlach, Christopher Untucht, Alfred Stefan
    Pages 257-275Open Access
  14. Data Storage

    • Christopher Frederick Isambard Blumzon, Adrian-Tudor Pănescu
    Pages 277-297Open Access
  15. Design of Meta-Analysis Studies

    • Malcolm R. Macleod, Ezgi Tanriver-Ayder, Kaitlyn Hair, Emily Sena
    Pages 299-317Open Access
  16. Quality Governance in Biomedical Research

    • Anja Gilis
    Pages 349-365Open Access
  17. Good Research Practice: Lessons from Animal Care and Use

    • Javier Guillén, Thomas Steckler
    Pages 367-382Open Access

About this book

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Editors and Affiliations

  • Partnership for Assessment & Accreditation of Scientific Practice, Heidelberg, Germany

    Anton Bespalov

  • Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany

    Martin C. Michel

  • Janssen Pharmaceutica N.V., Beerse, Belgium

    Thomas Steckler

Bibliographic Information

Buy it now

Buying options

Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access