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Bioinformatics

Volume II: Structure, Function, and Applications

  • Book
  • © 2017

Overview

Editors:
  1. Jonathan M. Keith

    1. Monash University, Melbourne, Australia

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1526)

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Table of contents (21 protocols)

  1. Computational Methods

    1. Front Matter

      Pages 327-327
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    2. Inference Method for Developing Mathematical Models of Cell Signaling Pathways Using Proteomic Datasets

      • Tianhai Tian, Jiangning Song
      Pages 329-344

    3. Clustering

      • G. J. McLachlan, R. W. Bean, S. K. Ng
      Pages 345-362

    4. Parameterized Algorithmics for Finding Exact Solutions of NP-Hard Biological Problems

      • Falk Hüffner, Christian Komusiewicz, Rolf Niedermeier, Sebastian Wernicke
      Pages 363-402

    5. Information Visualization for Biological Data

      • Tobias Czauderna, Falk Schreiber
      Pages 403-415

  2. Back Matter

    Pages 417-426
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Keywords

About this book

This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detailand expert implementation advice to ensure positive results.

Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research.

Reviews

“The book is as an excellent starting point for a wide audience including undergraduates, graduates and established researchers alike. The amount of detail presented for each methodological approach, coupled with extensive examples, facilitate not only the understanding of the topic but also the bridging between the various tasks associated with the mining of big (high throughput) biological datasets.” (Irina Ioana Mohorianu, zbMATH, Vol. 1384.92002, 2018)

Editors and Affiliations

  • Monash University, Melbourne, Australia

    Jonathan M. Keith

Bibliographic Information

  • Book Title: Bioinformatics

  • Book Subtitle: Volume II: Structure, Function, and Applications

  • Editors: Jonathan M. Keith

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-6613-4

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-1-4939-6611-0Published: 29 November 2016

  • Softcover ISBN: 978-1-4939-8250-9Published: 06 July 2018

  • eBook ISBN: 978-1-4939-6613-4Published: 26 November 2016

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XI, 426

  • Number of Illustrations: 62 b/w illustrations, 26 illustrations in colour

  • Topics: Bioinformatics

  • Industry Sectors: Biotechnology

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