Overview
- Authors:
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Ulrich Hübscher
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University of Zurich, Zurich, Switzerland
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Silvio Spadari
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Institute of Biochemical and Evolutionary Genetics, CNR, Pavia, Italy
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Table of contents (58 chapters)
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Proteins Acting at the Origin of DNA Replication
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Front Matter
Pages 183-183
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- Gian Paolo Dotto, Kensuke Horiuchi, Norton D. Zinder
Pages 185-191
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- Luis Blanco, Juan A. García, José M. Lázaro, Margarita Salas
Pages 193-197
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- Tove Atlung, Erik Clausen, Flemming G. Hansen
Pages 199-207
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- G. Churchward, P. Linder, L. Caro
Pages 209-214
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- D. W. Banner, R. M. Lacatena, L. Castagnoli, M. Cornelissen, G. Cesareni
Pages 215-219
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- A. D. M. Van Mansfeld, P. D. Baas, H. S. Jansz
Pages 221-230
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- A. C. Fluit, P. D. Baas, H. S. Jansz, G. H. Veeneman, J. H. van Boom
Pages 231-240
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- E. Fanning, C. Burger, B. Huber, U. Markau, S. Sperka, S. Thompson et al.
Pages 241-248
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- S. Litvak, J. Graveline, L. Zourgui, P. Carvallo, A. Solari, H. Aoyama et al.
Pages 249-262
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DNA Primase
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Front Matter
Pages 263-263
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- Erich Lanka, Jens P. Fürste
Pages 265-280
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- P. Plevani, G. Magni, M. Foiani, L. M. S. Chang, G. Badaracco
Pages 281-286
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- Michel Philippe, Rose Sheinin, Anne-Marie De Recondo
Pages 295-305
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- Gerhard Krauss, Frank Grosse
Pages 307-311
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DNA Polymerases and Accessory Proteins
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Front Matter
Pages 313-313
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- C. S. McHenry, K. O. Johanson
Pages 315-319
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- Ulrich Hübscher, Hans-Peter Ottiger
Pages 321-330
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- E. Schneider, B. Müller, R. Schindler
Pages 331-335
About this book
This book collects the Proceedings of a workshop sponsored by the European Molecular Biology Organization (EMBO) entitled "Pro teins Involved in DNA Replication" which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland. The aim of this workshop was to review and discuss the status of our knowledge on the intricate array of enzymes and proteins that allow the replication of the DNA. Since the first discovery of a DNA polymerase in Escherichia coli by Arthur Kornberg twenty eight years ago, a great number of enzymes and other proteins were des cribed that are essential for this process: different DNA poly merases, DNA primases, DNA dependent ATPases, helicases, DNA liga ses, DNA topoisomerases, exo- and endonucleases, DNA binding pro teins and others. They are required for the initiation of a round of synthesis at each replication origin, for the progress of the growing fork, for the disentanglement of the replication product, or for assuring the fidelity of the replication process. The number, variety and ways in which these proteins inter act with DNA and with each other to the achievement of replication and to the maintenance of the physiological structure of the chromo somes is the subject of the contributions collected in this volume. The presentations and discussions during this workshop reinforced the view that DNA replication in vivo can only be achieved through the cooperation of a high number of enzymes, proteins and other cofactors.
Authors and Affiliations
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University of Zurich, Zurich, Switzerland
Ulrich Hübscher
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Institute of Biochemical and Evolutionary Genetics, CNR, Pavia, Italy
Silvio Spadari