Overview
- Editors:
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Cees Th. Smit Sibinga
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Red Cross Blood Bank Groningen-Drenthe, The Netherlands
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Prakash C. Das
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Red Cross Blood Bank Groningen-Drenthe, The Netherlands
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C. Paul Engelfriet
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Central Laboratory of the Netherlands Red Cross, Amsterdam, The Netherlands
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Table of contents (26 papers)
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Production Aspects
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- M. K. Elias, H. Pol, M. Weggemans, A. Maas, P. C. Das, C. Th. Smit Sibinga
Pages 163-174
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- F. G. Arnaud, Ch. J. Hunt, D. E. Pegg
Pages 175-187
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- M. Körbling, W. Hunstein, H. Martin, R. Haas, P. Reichardt
Pages 207-223
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- M. K. Brenner, J.-P. Grob, H. G. Prentice
Pages 225-236
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Back Matter
Pages 237-241
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Laboratory Aspects
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- J. W. Smit, J. T. M. de Wolf, M. T. Esselink, M. J. A. van Luyn, N. R. Blom, T. Cazemier et al.
Pages 249-260
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- A. E. G. Kr. von dem Borne, W. H. Ouwehand, C. M. van Dalen
Pages 261-267
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- P. Champeix, C. Kaplan, M. Roche, C. Motta
Pages 269-272
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- F. Rey, F. Barre-Sinoussi, J. C. Chermann
Pages 273-280
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Back Matter
Pages 281-283
About this book
As a clinical discipline blood transfusion encompasses enormous vista, vary ing from biotechnology to molecular biology, from plasma products, cell biology and growth factors to interleukines. Growth of knowledge in this field has been rapid, and expertise is now required to be mastered and renewed in translating these ideas for patient care. Various types of cells could be harvested - progenitor stem cells derived from bone marrow or from circulating blood as a source for transplants; in the hemostatic armoury platelets could be used prophylactically; granulocytes and mononuclear cells are available for treatment of infections or immune modulations. However, their therapeutic use carries potential complications including graft versus host disease and CMV-infection. Prevention of such complications by irradiation and by removal of immunocompetent leukocytes are important issues. Thus, production of such therapeutic materials ought to address the issues at the earliest, to eliminate those problems while adhering to the con cept of high quality; the impact of storing platelets for longer periods by using improved plastic containers or storing almost indefinitely in frozen state should be explored. Rapid progress in cell culture techniques and bio technology have enriched the transfusion medicine armoury with lympho kines, interferons and cell colony growth factors which have great potentials for enhancement of basic knowledge as well as considerable therapeutic applications in patients.