Abstract
When transfused, HLA antigens, expressed on granulocytes and lymphocytes, are capable of stimulating the production of HLA alloantibodies in the recipient. These antibodies are responsible for two distinct clinical syndromes: non-hemolytic febrile transfusion reaction (NHFTR), seen in patients receiving multiple blood transfusions, and refractoriness platelet, seen in patients on long-term platelet support.
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© 1987 Martinus Nijhoff Publishing, Boston
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Brozovic, B. (1987). Preparation Of Leukocyte-Poor Blood. In: Sibinga, C.T.S., Das, P.C., Engelfriet, C.P. (eds) White cells and platelets in blood transfusion. Developments in Hematology and Immunology, vol 19. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2089-0_19
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DOI: https://doi.org/10.1007/978-1-4613-2089-0_19
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