Abstract.
During the last decade, great advances have been made concerning the construction and manipulation of nanostructures. As a consequence, nanometer stability and control of the sample position have became crucial points. For this purpose, we have built an optical microscope with high mechanic stability and we have implemented a feedback system in order to compensate thermal drifts. We demonstrate the system stability to be within one nanometer, with a control on the sample position of some micrometers, along the three spatial directions. The sample can be manipulated optically by means of a multiple optical tweezers setup and its displacements measured with a 3D position detector. We discuss and characterize the system properties thoroughly. We finally test the apparatus on a bio-molecular system constituted by a single myosin motor interacting with an actin filament.
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Capitanio, M., Cicchi, R. & Pavone, F. Position control and optical manipulation for nanotechnology applications. Eur. Phys. J. B 46, 1–8 (2005). https://doi.org/10.1140/epjb/e2005-00232-2
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DOI: https://doi.org/10.1140/epjb/e2005-00232-2