In Vitro Activity of Organochalcogen Compounds: III. Cytotoxic Effect of 4-(2-Hydroxyaryl)-1,2,3-thiadiazoles Against K562 and Hela Tumor Cell Lines

Abstract

In vitro antitumor activity of some 4-(2-hydroxyaryl)-1,2,3-thidiazoles was studied against erythroleukemia (K562) and cervical carcinoma (HeLa) cell lines.

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    Tests were performed according to manufacturer protocol https://www.gbiosciences.com/Bioassays/Alamar-Blue-Cell-Viability-Assay

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Funding

This work is supported by the Russian Science Foundation under grant 20-15-00332.

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Correspondence to E. A. Popova or V. M. Boitsov.

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No conflict of interest was declared by the authors.

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For communication II, see [1].

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Popova, E.A., Kornev, A.A., Bessonov, V.V. et al. In Vitro Activity of Organochalcogen Compounds: III. Cytotoxic Effect of 4-(2-Hydroxyaryl)-1,2,3-thiadiazoles Against K562 and Hela Tumor Cell Lines. Russ J Gen Chem 90, 2400–2404 (2020). https://doi.org/10.1134/S1070363220120270

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Keywords:

  • 4-(2-hydroxyaryl)-1,2,3-thidiazoles
  • in vitro antitumor activity
  • erythroleukemia (K562) cell line
  • cervical carcinoma (HeLa) cell line