Abstract
In vitro antitumor activity of some 4-(2-hydroxyaryl)-1,2,3-thidiazoles was studied against erythroleukemia (K562) and cervical carcinoma (HeLa) cell lines.
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REFERENCES
Popova, E.A., A.A. Kornev, Shmakov, S.V., Nepochatyi, G.D., Kotyunina, O.A., Petrov, M.L., Boitsov, V.M., and Stepakov, A.V., Russ. J. Gen. Chem., 2020, vol. 90, no. 11, p. 2214. https://doi.org/10.1134/S107036322011033X
Zhan, P., Liu, X.Y., Li, Z.Y., Fang, Z.J., Li, Z., Wang, D.F., Pannecouque, C., and Clercq, E.D., Bioorg. Med. Chem., 2009, vol. 17, no. 16, p. 5920. https://doi.org/10.1016/j.bmc.2009.07.004
Wu, M.J., Sun, Q.M., Yang, C.H., Chen, D.D., Ding, J., Chen, Y., Lin, L.P., and Xie, Y.Y., Bioorg. Med. Chem. Lett., 2007, vol. 17, no. 4, p. 869. https://doi.org/10.1016/j.bmcl.2006.11.060
Wang, T.T., Bing, G.F., Zhang, X., Qin, Z.F., Yu, H.B., Qin, X., Dai, H., and Fang, J.X., ARKIVOC, 2010, p. 330. https://doi.org/10.3998/ark.5550190.0011.228
Wang, Z.H., Guo, Y.Z., Zhang, J., Ma, L., Song, H.B., and Fan, Z.J., J. Agric. Food. Chem., 2010, vol. 58, no. 5, p. 2715. https://doi.org/10.1021/jf902168d
Wang, H., Yang, Z.K., Fan, Z.J., Wu, Q.J., Zhang, Y.J., Mi, N., Wang, S.X., Zhang, Z.C., Song, H.B., and Liu, F., J. Agric. Food. Chem., 2011, vol. 59, no. 2, p. 628. https://doi.org/10.1021/jf104004q
Dong, W.-L., Liu, Z.-X., Liu, X.-H., Li, Z.-M., and Zhao, W.-G., Eur. J. Med. Chem., 2010, vol. 45, no. 5, p. 1919. https://doi.org/10.1016/j.ejmech.2010.01.032
Pannecouque, C., Szafarowicz, B., Volkova, N., Bakulev, V., Dehaen, W., Mély, Y., and Daelemans, D., Antimicrob. Agents. Chemother., 2010, vol. 54, no. 4, p. 1461. https://doi.org/10.1128/AAC.01671-09
Petrov, M.L., Yekhlef, M., Teplyakov, F.S., and Androsov, D.A., Russ. J. Org. Chem., 2012, vol. 48, no. 5, p. 728. https://doi.org/10.1134/S1070428012050168
Petrov, M.L., Dehaen, W., Abramov, M.A., Abramova, I.P., Androsov, D.A., Russ. J. Org. Chem., 2002, vol. 38, no. 10, p. 1510. https://doi.org/10.1023/A:1022568808446
Shafran, Y., Glukhareva, T., Dehaen, W., and Bakulev, V., Adv. Heterocycl. Chem., 2018, vol. 126, p. 109. https://doi.org/10.1016/bs.aihch.2017.12.001
Tests were performed according to manufacturer protocol https://www.gbiosciences.com/Bioassays/Alamar-Blue-Cell-Viability-Assay
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This work is supported by the Russian Science Foundation under grant 20-15-00332.
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For communication II, see [1].
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Popova, E.A., Kornev, A.A., Bessonov, V.V. et al. In Vitro Activity of Organochalcogen Compounds: III. Cytotoxic Effect of 4-(2-Hydroxyaryl)-1,2,3-thiadiazoles Against K562 and Hela Tumor Cell Lines. Russ J Gen Chem 90, 2400–2404 (2020). https://doi.org/10.1134/S1070363220120270
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DOI: https://doi.org/10.1134/S1070363220120270