Abstract
To standardize studies on the utilization and consumption of drugs, the World Health Organization recommends the use of the Anatomical Therapeutic Chemical (ATC) classification system, using the defined daily dose (DDD value) as a technical unit of measurement of drug consumption, DDD values of total parenteral nutrition have not been established yet. In our descriptive study the methodology by E. Frankfort et al. (1993) [3] is used. This methodology allows the calculation of both the total number of DDD values for TPN and the number of DDD values for the individual substances. Suggested DDD values and consumption of total parenteral nutrition by E. Frankfort et al. (1994) [4] were compared with the values at the Teaching Hospital in Hradec Králové. During 3 months 142 patients administered only TPN were included in the study. The following data from every patient were collected: sex, age, the main diagnosis, composition of TPN each day and duration of this administration. The mean PDD value for carbohydrates was 200 ± 41 g. for fat emulsion 77 ± 27 g and for amino acids 93 ± 16 g. The difference between our and Frankfort's results were found.
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References
WHO Collaborating centre for Drug Statistics Methodology/ Nordic Council on Medicines. Guidelines for DDD. Oslo, 1993.
WHO Collaborating centre for Drug Statistics Methodology/ Nordic Council on Medicines. Guidelines for ATC classification. Oslo, 1993.
Frankfort E, Zimmerman C, Van Dalen R, Hekster YA. Utilization patterns of total parenteral nutrition in a university hospital. Pharm World Sci 1993;15(2):68–72.
Frankfort E, Zimmerman C, Borm GF, Van Dalen R, Hekster YA. Analysis of total parenteral nutrition utilization in intensive-care patients. Pharm World Sci 1994;16(5):225–30.
Brodanová M, Anděl M. Infuzní terapie, parenterální a enterální výživa. Praha: Grada, 1994.
Hill GL. Body Composition Research: Implications for the Practice of Clinical Nutrition. JPEN 1992;16(3):197–218.
Allison SP. The uses and limitations of nutritional support. Clinical Nutrition 1992;11:319–30.
Elia M. Artifical nutrition support: some new frontiers. Clinical Nutrition 1993;12(Suppl 1):2–5.
Guiaro X, Franch G, Gil MJ, Garcia-Domingo MI, Girvent M, Sitges-Serra A. Extracellular volume, nutritional status, and reffending changes. Nutrition 1994;10(6):558–61.
American Society for Parenteral and Enteral Nutrition. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. JPEN 1993;17(4):5SA–32SA.
Schotic DC. Recommended daily allowance of maintenance parenteral nutrition in infants and children. Am J Health-Syst Pharm 1995;52:651–3.
Roberts SB, Fuss P, Heyman MB, Young VR. Influence of age on energy requirements. Am J Clin Nutr 1995;62(suppl): 1053S–8S.
Flatt JP. Body composition, respiratory quotients, and weight maintenance. Am J Clin Nutr 1995;62(suppl):1107S–17S.
Johnson RK, Goran MI, Poehlman ET. Correlates of over-and underreportin of energy intake in healthy older men and women. Am J Clin Nutr 1994;59:1286–90.
Hill GL, Windsor JA. Nutritional Assessment in Clinical Practice. Nutrition 1995;11(2):198–201.
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Jandová, M., Vlček, J., Klemerová, V. et al. Monitoring of TPN consumption at the University Teaching Hospital in Hradec Králové. Pharm World Sci 20, 28–31 (1998). https://doi.org/10.1023/A:1008698010775
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DOI: https://doi.org/10.1023/A:1008698010775