Abstract
Box-Behnken design was utilized to obtain optimized process condition for maximizing lactic acid extraction efficiency and initial extraction rate by emulsion liquid membrane (ELM) process. A mixture of tri-n-octylamine and tri-n-decylamine (1:1, v/v) was employed as carrier in membrane phase of ELM for synergic facilitated lactic acid transport. The effect of different process parameters like lactic acid concentration in feed, sodium carbonate concentration in internal phase, carrier fraction, treatment ratio, phase ratio, stirring speed and contact time has been investigated. Extraction efficiency of 98.5% and 9.36 × 10−9 mol/cm2.sec, initial extraction rate were found under optimized conditions of process parameters.
Similar content being viewed by others
References
Ahmad AL, Buddin MMHS, Ooi BS, Kusumastuti A (2017) Utilization of environmentally benign emulsion liquid membrane (ELM) for cadmium extraction from aqueous solution. J Water Process Eng 15:26–30
Anitha M, Ambare DN, Singh DK, Singh H, Mohapatra PK (2015) Extraction of neodymium from nitric acid feed solutions using an emulsion liquid membrane containing TOPO and DNPPA as the carrier extractants. Chem Eng Res Des 98:89–95
Babu VS, Kumar SS, Murali RV, Rao MM (2011) Investigation and validation of optimal cutting parameters for least surface roughness in EN24 with response surface method. Inter J Eng, Sci and Technol 3(6):146–160
Basualto C, Poblete M, Marchese J, Ochoa A, Acosta A, Sapaga J, Valenzuela F (2006) Extraction of cadmium from aqueous solutions by emulsion liquid membranes using a stirred transfer cell contactor. J Braz Chem Soc 17(7):1347–1354
Benyahia N, Belkhouche N, Jonsson JA (2014) A comparative study of experimental optimization and response surface methodology of bi(III) extraction by emulsion organophosphorus liquid membrane. J Environ Chem Eng 2:1756–1766
Berrios J, Pyle DL, Aroca G (2010) Gibberellic acid extraction from aqueous solutions and fermentation broths by using emulsion liquid membranes. J Membr Sci 348:91–98
Chanukya BS, Rastogi NK (2013) Extraction of alcohol from wine and color extracts using liquid emulsion membrane. Sep Purif Technol 105:41–47
Daas A, Hamdaoui O (2010) Extraction of bisphenol a from aqueous solutions by emulsion liquid membrane. J Membr Sci 348:360–368
Datta S, Bhattacharya PK, Verma N (2003) Removal of aniline from aqueous solution in a mixed flow reactor using emulsion liquid membrane. J Membr Sci 226:185–201
Eyupoglu V, Kumbasar RA (2015) Extraction of Ni(II) from spent Cr-Ni electroplating bath solutions using LIX 63 and 2BDA as carriers by emulsion liquid membrane technique. J Ind Eng Chem 21:303–310
Gao MT, Shimamura T, Ishida N, Takahashi H (2009) Application of metabolically engineered Saccharomyces cerevisiae to extractive lactic acid fermentation. Biochem Eng J 44:251–255
Garavand F, Razavi SH, Cacciotti I (2017) Synchronized extraction and purification of L-lactic acid from fermentation broth by emulsion liquid membrane (ELM) technique. J Dispers Sci Technol. https://doi.org/10.1080/01932691.2017.1396225
Garcia MG, Acosta AO, Marchese J (2013) Emulsion liquid membrane pertraction of Cr(III) from aqueoussolutions using PC-88A as carrier. Desalination 318:88–96
Goyal RK, Jayakumar NS, Hashim MA (2011) A comparative study of experimental optimization and response surface optimization of Cr removal by emulsion ionic liquid membrane. J Hazard Mater 195:383–390
Goyal RK, Jayakumar NS, Hashim MA (2011a) Chromium removal by emulsion liquid membrane using [BMIM]+[NTf2]− as stabilizer and TOMAC as extractant. Desalination 278:50–56
Hachemaoui A, Belhamel K (2017) Simultaneous extraction and separation of cobalt and nickel from chloride solution through emulsion liquid membrane using Cyanex 301 as extractant. Int J Miner Process 161:7–12
Hong YK, Hong WH (1999) Reactive extraction of lactic acid with mixed tertiary amine extractants. Biotechnol Tech 13:915–918
Hong L, Yimin Z, Jing H, Tao L, Nannan X, Kui W (2017) Selective separation and recovery of vanadium from a multiple impurity acid leaching solution ofstone coal by emulsion liquid membrane using di-(2-ethylhexyl) phosphoric acid. Chem Eng Res Des 122:289–297
Jiao H, Peng W, Zhao J, Xu C (2013) Extraction performance of bisphenol a from aqueous solutions by emulsion liquid membrane using response surface methodology. Desalination 313:36–43
John RP, Nampoothiri KM, Pandey A (2007) Fermentative production of lactic acid from biomass:an overview on process developments and future perspectives. Appl Microb Biotechnol 74:524–534
Keshav A, Norge P, Wasewar KL (2012) Reactive extraction of citric acid using tri-n-octylamine in nontoxic natural diluents: part 1-equilibrium studies from aqueous solutions. Appl Biochem Biotechnol 167:197–213
Kimberley AC, Taylor CA (1996) A simple colorimetric assay for muramic acid and lactic acid. Appl Biochem Biotechnol 56:49–58
Kumbasar RA (2010) Extraction and concentration of cobalt from acidic leach solutions containing co-Ni by emulsion liquid membrane using TOA as extractant. J Ind Eng Chem 16:448–454
Kumbasar RA (2012) Selective transport of cobalt (II) from ammoniacal solutions containing cobalt (II) and nickel (II) by emulsion liquid membranes using 8-hydroxyquinoline. J Ind and Eng Chem 18:145–151
Kyuchoukov G, Marinova M, Molinier J, Albet J, Malmary G (2001) Extraction of lactic acid by means of a mixed extractant. Ind & Eng Chem Res 40:5635–5639
Lee SC (2011) Extraction of succinic acid from simulated media by emulsion liquid membranes. J Membr Sci 381:237–243
Lee SC (2013) Development of an emulsion liquid membrane system for removal of acetic acid from xylose and sulfuric acid in a simulated hemicellulosic hydrolysate. Sep and Purif Technol 118:540–546
Li Y, Shahbazi A (2006) Lactic acid recovery from cheese whey fermentation broth using combined ultrafiltration and nanofiltration membranes. Appl Biochem Biotechnol 132(1–3):985–996
Mesli M, Belkhouche N-E (2018) Emulsion ionic liquid membrane for recovery process of lead. Comparative study of experimental and response surface design. Chem Eng Res Des 129:160–169
Mousavi SM, Kiani S, Farmad MR, Hemati A, Abbasi B (2012) Extraction of arsenic(V) from water using emulsion liquid membrane. J Disper Sci Tech 33:123–129
Ng YS, Jayakumar NS, Hashim MA (2010) Performance evaluation of organic emulsion liquid membrane on phenol removal. J Hazard Mater 184:255–260
Noah NFM, Othman N, Jusoh N (2016) Highly selective transport of palladium from electroplating wastewater using emulsion liquid membrane process. J Taiwan Inst Chem Eng 64:134–141
Patti GCA, Llinàs M, García-Celma MJ (2012) Diffusion in highly concentrated emulsions. Curr Opin Colloid Interface Sci 17:255–260
Peng W, Jiao H, Shi H, Xu C (2012) The application of emulsion liquid membrane process and heat-induced demulsification for removal of pyridine from aqueous solutions. Desalination 286:372–378
Pimtong, V.; Ounaeb, S.; Thitiprasert, S.; Tolieng,V.; Sooksai, S.; Boonsombat, R.; Tanasupawat, S.; Assabumrungrat, S.; Thongchul, N. (2017) Enhanced effectiveness of Rhizopus oryzae by immobilization in a static bed fermentor for l-lactic acid production. Process Biochem 52: 44–52
Rajasimman M, Karthic P (2010) Application of response surface methodology for the extraction of chromium (VI) by emulsion liquid membrane. J Taiw Inst Chem Eng 41:105–110
Reis MT, Freitas OM, Agarwal S, Ferreira LM, Ismael MR, Machado R, Carvalho JM (2011) Removal of phenols from aqueous solutions by emulsion liquid membranes. J Hazard Mater 192(3):986–994
Uslu H, Bayat C, Gokmen S, Yorulmaz Y (2009) Reactive extraction and LSER model consideration of lactic acid with tripropylamine+ organic solvent systems from aqueous solution at room temperature. Desalination 249:694–698
Venus J, Fiore S, Demichelis F, Pleisser D (2018) Centralized and decentralized utilization of organic residues for lactic acid production. J Clean Prod 172:778–785
Yankov D, Molinier J, Albet J, Malmary G, Kyuchoukov G (2004) Lactic acid extraction from aqueous solutions with tri-n-octylamine dissolved in decanol and dodecane. BiochemEng J 21:63–71
Yetilmezsoy K, Demirel S, Vanderbei RJ (2009) Response surface modeling of Pb(II) removal from aqueous solution by Pistaciavera L.: box-Behnken experimental design. J Hazard Mater 171:551–562
Yordanov B, Boyadzhiev L (2004) Pertraction of citric acid by means of emulsion liquid membranes. J Membr Sci 238:191–197
Yu L, Lei T, Ren X, Pei X, Feng Y (2008) Response surface optimization of l-(+)-lactic acid production using corn steep liquor as an alternative nitrogen source by Lactobacillus rhamnosus CGMCC 1466. Biochem Eng J 39:496–450
Acknowledgements
Author is grateful to Sant Longowal Institute of Engineering and Technology, Longowal, India for providing the lab facilities and all necessary help to perform this research work.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Thakur, A. Lactic Acid Extraction from Aqueous Systems by Emulsion Liquid Membrane Separation Process Using Statistical Experimental Design. Polytechnica 2, 62–76 (2019). https://doi.org/10.1007/s41050-019-00015-0
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s41050-019-00015-0