ChemTexts

, 4:3 | Cite as

Lipids at the air–water interface

Lecture Text
  • 103 Downloads

Abstract

Lipids are important natural chemical compounds, as they comprise the major component in biological membranes. Biological membranes are composed of lipids in a bilayer structure and proteins incorporated into the bilayers or bound to the bilayer surface. Due to the amphiphilic nature of lipids, they self-assemble in aqueous solution into a variety of lyotropic phases, the most important one being the lamellar phase made up of stacks of lipid bilayers separated by water layers. The bilayer structure can be easily produced by dispersing lipids in water. Lipids are amphiphilic structures built up of a polar headgroup and one or two hydrophobic alkyl chains. They are, therefore, surface active and form the so-called insoluble monolayers or Langmuir films at the air–water interface. These monolayers resemble half of a lipid bilayer and are, therefore, widely used as model systems for bilayer membranes. In this review, the properties and the phase behavior of phospholipid monolayers, as well as the techniques used for studying these monolayers will be described. In addition, examples for the information gained using different techniques will be shown.

Keywords

Lipid monolayers Langmuir trough Monolayer characterization methods Infrared reflection absorption spectroscopy Epifluorescence microscopy 

Notes

Acknowledgements

This work was supported by Grants from the Deutsche Forschungsgemeinschaſt (DFG), the state of Saxonia-Anhalt, the Phospholipid Research Center, Heidelberg, Germany, and Boehringer Ingelheim GmbH and Co, Ingelheim, Germany. I want to express my gratitude to all members of my group for their contributions to the research results presented here in this review.

References

  1. 1.
    Singer SJ, Nicolson GL (1972) Fluid mosaic model of structure of cell membranes. Science 175(4023):720–731.  https://doi.org/10.1126/science.175.4023.720 CrossRefGoogle Scholar
  2. 2.
    Nicolson GL (2014) The fluid-mosaic model of membrane structure: still relevant to understanding the structure, function and dynamics of biological membranes after more than 40 years. Biochim Biophys Acta 1838(6):1451–1466.  https://doi.org/10.1016/j.bbamem.2013.10.019 CrossRefGoogle Scholar
  3. 3.
    Bagatolli LA, Ipsen JH, Simonsen AC, Mouritsen OG (2010) An outlook on organization of lipids in membranes: searching for a realistic connection with the organization of biological membranes. Prog Lipid Res 49(4):378–389.  https://doi.org/10.1016/j.plipres.2010.05.001 CrossRefGoogle Scholar
  4. 4.
    Gennis RB (1990) Biomembranes: molecular structure and function. Springer-Verlag, New YorkGoogle Scholar
  5. 5.
    Buehler LK (2016) Cell membranes. Garland Science, New YorkGoogle Scholar
  6. 6.
    Adamson AW, Gast AP (1997) Physical chemistry of surfaces, 6th edn. Wiley, New YorkGoogle Scholar
  7. 7.
    Butt H-J, Graf K, Kappl M (2013) Physics and chemistry of interfaces, 3rd edn. Wiley-VCH, WeinheimGoogle Scholar
  8. 8.
    Evans RW (1995) Aggregates of saturated phospholipids at the air-water interface. Chem Phys Lipids 78(2):163–175.  https://doi.org/10.1016/0009-3084(95)02495-5 CrossRefGoogle Scholar
  9. 9.
    Blume A (1979) A comparative study of the phase transitions of phospholipid bilayers and monolayers. Biochim Biophys Acta 557(1):32–44.  https://doi.org/10.1016/0005-2736(79)90087-7 CrossRefGoogle Scholar
  10. 10.
    Brockman H (1999) Lipid monolayers: why use half a membrane to characterize protein-membrane interactions?. Curr Opin Struct Biol 9(4):438–443.  https://doi.org/10.1016/s0959-440x(99)80061-x CrossRefGoogle Scholar
  11. 11.
    Maget-Dana R (1999) The monolayer technique: a potent tool for studying the interfacial properties of antimicrobial and membrane-lytic peptides and their interactions with lipid membranes. Biochim Biophys Acta 1462(1–2):109–140.  https://doi.org/10.1016/s0005-2736(99)00203-5 CrossRefGoogle Scholar
  12. 12.
    Möhwald H (1990) Phospholipid and phospholipid-protein monolayers at the air-water interface. Annu Rev Phys Chem 41:441–476CrossRefGoogle Scholar
  13. 13.
    Giner-Casares JJ, Brezesinski G, Möhwald H (2014) Langmuir monolayers as unique physical models. Curr Opin Colloid Interface Sci 19(3):176–182.  https://doi.org/10.1016/j.cocis.2013.07.006 CrossRefGoogle Scholar
  14. 14.
    Stefaniu C, Brezesinski G, Mohwald H (2014) Langmuir monolayers as models to study processes at membrane surfaces. Adv Colloid Interface Sci 208:197–213.  https://doi.org/10.1016/j.cis.2014.02.013 CrossRefGoogle Scholar
  15. 15.
    Pichot R, Watson R, Norton I (2013) Phospholipids at the interface: current trends and challenges. Int J Mol Sci 14(6):11767–11794.  https://doi.org/10.3390/ijms140611767 CrossRefGoogle Scholar
  16. 16.
    Giehl A, Lemm T, Bartelsen O, Sandhoff K, Blume A (1999) Interaction of the GM2-activator protein with phospholipid–ganglioside bilayer membranes and with monolayers at the air–water interface. Eur J Biochem 261(3):650–658.  https://doi.org/10.1046/j.1432-1327.1999.00302.x CrossRefGoogle Scholar
  17. 17.
    Calvez P, Bussières S, Éric D, Salesse C (2009) Parameters modulating the maximum insertion pressure of proteins and peptides in lipid monolayers. Biochimie 91(6):718–733.  https://doi.org/10.1016/j.biochi.2009.03.018 CrossRefGoogle Scholar
  18. 18.
    Kaganer VM, Möhwald H, Dutta P (1999) Structure and phase transitions in Langmuir monolayers. Rev Mod Phys 71(3):779–819.  https://doi.org/10.1103/RevModPhys.71.779 CrossRefGoogle Scholar
  19. 19.
    Stefaniu C, Brezesinski G (2014) Grazing incidence X-ray diffraction studies of condensed double-chain phospholipid monolayers formed at the soft air/water interface. Adv Colloid Interface Sci 207:265–279.  https://doi.org/10.1016/j.cis.2014.01.005 CrossRefGoogle Scholar
  20. 20.
    Stefaniu C, Brezesinski G (2014) X-ray investigation of monolayers formed at the soft air/water interface. Curr Opin Colloid Interface Sci 19(3):216–227.  https://doi.org/10.1016/j.cocis.2014.01.004 CrossRefGoogle Scholar
  21. 21.
    Bangham AD, Mason W (1979) The effect of some general anaesthetics on the surface potential of lipid monolayers. Br J Pharmacol 66(2):259–265.  https://doi.org/10.1111/j.1476-5381.1979.tb13674.x CrossRefGoogle Scholar
  22. 22.
    Cadenhead DA, Kellner BMJ (1974) Some observations on monolayer spreading solvents with special reference to phospholipid monolayers. J Colloid Interface Sci 49(1):143–145.  https://doi.org/10.1016/0021-9797(74)90311-7 CrossRefGoogle Scholar
  23. 23.
    Clarke RJ (2001) The dipole potential of phospholipid membranes and methods for its detection. Adv Colloid Interface Sci 89–90:263–281.  https://doi.org/10.1016/s0001-8686(00)00061-0 CrossRefGoogle Scholar
  24. 24.
    Haydon DA, Elliott JR (1986) Surface potential changes in lipid monolayers and the ‘cut-off’ in anaesthetic effects of N-alkanols. Biochim Biophys Acta 863(2):337–340.  https://doi.org/10.1016/0005-2736(86)90278-6 CrossRefGoogle Scholar
  25. 25.
    Wang L (2012) Measurements and implications of the membrane dipole potential. Annu Rev Biochem 81(1):615–635.  https://doi.org/10.1146/annurev-biochem-070110-123033 CrossRefGoogle Scholar
  26. 26.
    Lösche M, Duwe HP, Möhwald H (1988) Quantitative analysis of surface textures in phospholipid monolayer phase transitions. J Coll Interf Sci 126:432–444CrossRefGoogle Scholar
  27. 27.
    Lösche M, Möhwald H (1984) Impurity controlled phase transitions of phospholipid monolayers. Eur Biophys J 11:35–42CrossRefGoogle Scholar
  28. 28.
    McConnell HM (1984) Periodic structures in lipid monolayer phase transitions. Proc Natl Acad Sci USA 81:3249–3253CrossRefGoogle Scholar
  29. 29.
    Hönig D, Möbius D (1991) Direct visualization of monolayers at the air-water interface by Brewster angle microscopy. J Phys Chem 95(12):4590–4592.  https://doi.org/10.1021/j100165a003 CrossRefGoogle Scholar
  30. 30.
    Hénon S, Meunier J (1991) Microscope at the Brewster angle: direct observation of first-order phase transitions in monolayers. Rev Sci Instrum 62(4):936–939.  https://doi.org/10.1063/1.1142032 CrossRefGoogle Scholar
  31. 31.
    Mobius D (1996) Light microscopy of organized monolayers. Curr Opin Colloid Interface Sci 1(2):250–256.  https://doi.org/10.1016/s1359-0294(96)80012-4 CrossRefGoogle Scholar
  32. 32.
    Vollhardt D (2014) Brewster angle microscopy: a preferential method for mesoscopic characterization of monolayers at the air/water interface. Curr Opin Colloid Interface Sci 19(3):183–197.  https://doi.org/10.1016/j.cocis.2014.02.001 CrossRefGoogle Scholar
  33. 33.
    Blume A, Kerth A (2013) Peptide and protein binding to lipid monolayers studied by FT-IRRAS. Biochim Biophys Acta 1828(10):2294–2305.  https://doi.org/10.1016/j.bbamem.2013.04.014 CrossRefGoogle Scholar
  34. 34.
    Blaudez D, Buffeteau T, Desbat B, Turlet JM (1999) Infrared and Raman spectroscopies of monolayers at the air-water interface. Curr Opin Colloid Interface Sci 4:265–272CrossRefGoogle Scholar
  35. 35.
    Dluhy RA, Cornell DG (1985) In situ measurements of the infrared-spectra of insoluble monolayers at the air–water interface. J Phys Chem 89(15):3195–3197.  https://doi.org/10.1021/j100261a006 CrossRefGoogle Scholar
  36. 36.
    Mendelsohn R, Brauner JW, Gericke A (1995) External infrared reflection-absorption spectrometry of monolayer films at the air–water interface. Annu Rev Phys Chem 46:305–334.  https://doi.org/10.1146/annurev.physchem.46.1.305 CrossRefGoogle Scholar
  37. 37.
    Mendelsohn R, Mao GR, Flach CR (2010) Infrared reflection–absorption spectroscopy: principles and applications to lipid-protein interaction in Langmuir films. Biochim Biophys Acta 1798(4):788–800.  https://doi.org/10.1016/j.bbamem.2009.11.024 CrossRefGoogle Scholar
  38. 38.
    Chen X, Clarke ML, Wang JIE, Chen Z (2005) Sum frequency generation vibrational spectroscopy studies on molecular conformation and orientation of biological molecules at interfaces. Int J Mod Phys B 19(04):691–713.  https://doi.org/10.1142/s0217979205029341 CrossRefGoogle Scholar
  39. 39.
    Roke S, Schins J, Müller M, Bonn M (2003) Vibrational spectroscopic investigation of the phase diagram of a biomimetic lipid monolayer. Phys Rev Lett.  https://doi.org/10.1103/PhysRevLett.90.128101 Google Scholar
  40. 40.
    Watry MR, Tarbuck TL, Richmond GL (2003) Vibrational sum-frequency studies of a series of phospholipid monolayers and the associated water structure at the vapor/water interface. J Phys Chem B 107(2):512–518.  https://doi.org/10.1021/jp0216878 CrossRefGoogle Scholar
  41. 41.
    Blume A (2004) Lipids. In: Walz D, Teissié J, Milazzo G (eds) Bioelectrochemistry of membranes, vol V. Birkhäuser-Verlag, Basel, pp 61–152CrossRefGoogle Scholar
  42. 42.
    Bard AJ, Inzelt G, Scholz F (2012) Electrochemical dictionary, 2nd edn. Springer, BerlinGoogle Scholar
  43. 43.
    Wilhelmy L (1863) Ueber die Abhängigkeit der Capillaritäts-Constanten des Alkohols von Substanz und Gestalt des benetzten festen Körpers. Annalen der Physik Chemie 195(6):177–217.  https://doi.org/10.1002/andp.18631950602 CrossRefGoogle Scholar
  44. 44.
    Lee KYC (2008) Collapse mechanisms of Langmuir monolayers. Annu Rev Phys Chem 59(1):771–791.  https://doi.org/10.1146/annurev.physchem.58.032806.104619 CrossRefGoogle Scholar
  45. 45.
    Atkins P, de Paula J (2010) Physical chemistry, 9th edn edn. Oxford University Press, OxfordGoogle Scholar
  46. 46.
    Jaeger G (1998) The Ehrenfest classification of phase transitions: introduction and evolution. Arch Hist Exact Sci 53(1):51–81.  https://doi.org/10.1007/s004070050021 CrossRefGoogle Scholar
  47. 47.
    Gaines GL (1966) Insoluble monolayers at liquid–gas interfaces. Wiley Interscience, New YorkGoogle Scholar
  48. 48.
    Hoffmann S (1997) Struktur und Dynamik langkettiger 5-n-Alkylresorcinole in Phospholipidmodellmembranen, Ph.D., University of Kaiserslautern, KaiserslauternGoogle Scholar
  49. 49.
    Risović D, Frka S, Kozarac Z (2011) Application of Brewster angle microscopy and fractal analysis in investigations of compressibility of Langmuir monolayers. J Chem Phys 134(2):024701.  https://doi.org/10.1063/1.3522646 CrossRefGoogle Scholar
  50. 50.
    Caruso B, Mangiarotti A, Wilke N (2013) Stiffness of lipid monolayers with phase coexistence. Langmuir 29(34):10807–10816.  https://doi.org/10.1021/la4018322 CrossRefGoogle Scholar
  51. 51.
    Duncan SL, Larson RG (2008) Comparing experimental and simulated pressure-area isotherms for DPPC. Biophys J 94(8):2965–2986.  https://doi.org/10.1529/biophysj.107.114215 CrossRefGoogle Scholar
  52. 52.
    Crane JM, Putz G, Hall SB (1999) Persistence of phase coexistence in disaturated phosphatidylcholine monolayers at high surface pressures. Biophys J 77(6):3134–3143.  https://doi.org/10.1016/s0006-3495(99)77143-2 CrossRefGoogle Scholar
  53. 53.
    Adams EM, Casper CB, Allen HC (2016) Effect of cation enrichment on dipalmitoylphosphatidylcholine (DPPC) monolayers at the air–water interface. J Colloid Interface Sci 478:353–364.  https://doi.org/10.1016/j.jcis.2016.06.016 CrossRefGoogle Scholar
  54. 54.
    von Tscharner V, McConnell HM (1981) An alternative view of phospholipid phase behavior at the air–water interface. Microscope and film balance studies. Biophys J 36(2):409–419.  https://doi.org/10.1016/s0006-3495(81)84740-6 CrossRefGoogle Scholar
  55. 55.
    Träuble H, Eibl H (1974) Electrostatic effects on lipid phase transitions: membrane structure and ionic environment. Proc Natl Acad Sci USA 71(1):214–219CrossRefGoogle Scholar
  56. 56.
    Blume A, Eibl H (1979) The influence of charge on bilayer membranes calorimetric investigations of phosphatidic acid bilayers. Biochim Biophys Acta 558(1):13–21.  https://doi.org/10.1016/0005-2736(79)90311-0 CrossRefGoogle Scholar
  57. 57.
    Blume A, Tuchtenhagen J (1992) Thermodynamics of ion binding to phosphatidic acid bilayers. Titration calorimetry of the heat of dissociation of DMPA. Biochemistry 31(19):4636–4642.  https://doi.org/10.1021/bi00134a014 CrossRefGoogle Scholar
  58. 58.
    Eibl H, Blume A (1979) The influence of charge on phosphatidic acid bilayer membranes. Biochim Biophys Acta 553(3):476–488.  https://doi.org/10.1016/0005-2736(79)90303-1 CrossRefGoogle Scholar
  59. 59.
    Garidel P (1997) The negatively charged phospholipids phosphatidic acid and phosphatidylglycerol, Ph.D, University of Kaiserslautern, KaiserslauternGoogle Scholar
  60. 60.
    Garidel P, Blume A (2005) 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) monolayers: influence of temperature, pH, ionic strength and binding of alkaline earth cations. Chem Phys Lipids 138(1–2):50–59.  https://doi.org/10.1016/j.chemphyslip.2005.08.001 CrossRefGoogle Scholar
  61. 61.
    Kodama M, Shibata O, Nakamura S, Lee S, Sugihara G (2004) A monolayer study on three binary mixed systems of dipalmitoyl phosphatidyl choline with cholesterol, cholestanol and stigmasterol. Colloid Surf B Biointerface 33(3–4):211–226.  https://doi.org/10.1016/j.colsurfb.2003.10.008 CrossRefGoogle Scholar
  62. 62.
    Gerdon S, Hoffmann S, Blume A (1994) Properties of mixed monolayers and bilayers of long-chain 5-n-alkylresorcinols and dipalmitoylphosphatidylcholine. Chem Phys Lipids 71(2):229–243.  https://doi.org/10.1016/0009-3084(94)90074-4 CrossRefGoogle Scholar
  63. 63.
    Gaines GL (1966) Thermodynamic relationships for mixed insoluble monolayers. J Colloid Interface Sci 21(3):315–319.  https://doi.org/10.1016/0095-8522(66)90015-8 CrossRefGoogle Scholar
  64. 64.
    Hildebrandt HJ (1929) Solubility (XII). Regular solutions. J Am Chem Soc 51:66–80CrossRefGoogle Scholar
  65. 65.
    Garidel P, Johann C, Blume A (2000) Thermodynamics of lipid organization and domain formation in phospholipid bilayers. J Liposome Res 10(2–3):131–158. doi: https://doi.org/10.3109/08982100009029383 Google Scholar
  66. 66.
    Matuo H, Motomura K, Matuura R (1982) Interrelationships between two-dimensional phase diagrams and mean molecular area-mole fraction curves in mixed monolayers. Chem Phys Lipids 30(4):353–365.  https://doi.org/10.1016/0009-3084(82)90029-9 CrossRefGoogle Scholar
  67. 67.
    Matuo H, Motomura K, Matuura R (1982) Mixed monolayers of dipalmitoylglycerophosphocholine, distearoylglycerophosphocholine and 1-palmitoylglycerol. Chem Phys Lipids 31(1):53–60.  https://doi.org/10.1016/0009-3084(82)90018-4 CrossRefGoogle Scholar
  68. 68.
    Matuo H, Motomura K, Matuura R (1981) Effects of molecular structure on two-dimensional phase diagram and thermodynamic quantities of mixed monolayers. Chem Phys Lipids 28(4):385–397.  https://doi.org/10.1016/0009-3084(81)90024-4 CrossRefGoogle Scholar
  69. 69.
    Matuo H, Motomura K, Matuura R (1982) Mixed monolayers of fatty acids with distearoylglycerophosphocholine. Chem Phys Lipids 31(4):351–358.  https://doi.org/10.1016/0009-3084(82)90071-8 CrossRefGoogle Scholar
  70. 70.
    Stottrup BL, Nguyen AH, Tüzel E (2010) Taking another look with fluorescence microscopy: image processing techniques in Langmuir monolayers for the twenty-first century. Biochim Biophys Acta 1798(7):1289–1300.  https://doi.org/10.1016/j.bbamem.2010.01.003 CrossRefGoogle Scholar
  71. 71.
    Weis RM (1991) Fluorescence microscopy of phospholipid monolayer phase transitions. Chem Phys Lipids 57(2–3):227–239.  https://doi.org/10.1016/0009-3084(91)90078-p CrossRefGoogle Scholar
  72. 72.
    Scholtysek P, Li Z, Kressler J, Blume A (2012) Interactions of DPPC with semitelechelic poly(glycerol methacrylate)s with perfluoroalkyl endgroups. Langmuir 28(44):15651–15662.  https://doi.org/10.1021/la3028226 CrossRefGoogle Scholar
  73. 73.
    Scholtysek P (2014) Chirale und achirale Polymere in Wechselwirkung mit Phospholipid-Monolayern und—Bilayern. Ph.D., Martin-Luther-University Halle-Wittenberg, HalleGoogle Scholar
  74. 74.
    Cristofolini L (2014) Synchrotron X-ray techniques for the investigation of structures and dynamics in interfacial systems. Curr Opin Colloid Interface Sci 19(3):228–241.  https://doi.org/10.1016/j.cocis.2014.03.006 CrossRefGoogle Scholar
  75. 75.
    Flach CR, Brauner JW, Mendelsohn R (1993) Calcium ion interactions with insoluble phospholipid monolayer films at the A/W interface. External reflection-absorption IR studies. Biophys J 65(5):1994–2001.  https://doi.org/10.1016/s0006-3495(93)81276-1 CrossRefGoogle Scholar
  76. 76.
    Flach CR, Gericke A, Mendelsohn R (1997) Quantitative determination of molecular chain tilt angles in monolayer films at the air/water interface: Infrared reflection/absorption spectroscopy of behenic acid methyl ester. J Phys Chem B 101(1):58–65.  https://doi.org/10.1021/jp962288d CrossRefGoogle Scholar
  77. 77.
    Kerth A (2003) Infrarot-Reflexions-Absorptions-Spektroskopie an Lipid-, Peptid- und Flüssigkristall-Filmen an der Luft/Wasser-Grenzfläche. Ph.D., Martin-Luther-University Halle-Wittenberg, HalleGoogle Scholar
  78. 78.
    Kuzmin VL, Mikhailov AV (1981) Molecular theory of light reflection and applicability limits of the macroscopic approach. Opt Spectrosc (USSR) 51:383–385Google Scholar
  79. 79.
    Gericke A, Flach CR, Mendelsohn R (1997) Structure and orientation of lung surfactant SP-C and L-alpha-dipalmitoylphosphatidylcholine in aqueous monolayers. Biophys J 73(1):492–499CrossRefGoogle Scholar
  80. 80.
    Kerth A, Brehmer T, Meister A, Hanner P, Jakob M, Klösgen RB, Blume A (2012) Interaction of a tat substrate and a tat signal peptide with thylakoid lipids at the air–water interface. Chem Bio Chem 13(2):231–239.  https://doi.org/10.1002/cbic.201100458 CrossRefGoogle Scholar
  81. 81.
    Kerth A, Erbe A, Dathe M, Blume A (2004) Infrared reflection absorption spectroscopy of amphipathic model peptides at the air/water interface. Biophys J 86(6):3750–3758.  https://doi.org/10.1529/biophysj.103.035964 CrossRefGoogle Scholar
  82. 82.
    Meister A, Nicolini C, Waldmann H, Kuhlmann J, Kerth A, Winter R, Blume A (2006) Insertion of lipidated ras proteins into lipid monolayers studied by infrared reflection absorption spectroscopy (IRRAS). Biophys J 91(4):1388–1401.  https://doi.org/10.1529/biophysj.106.084624 CrossRefGoogle Scholar
  83. 83.
    Blume A (1996) Properties of lipid vesicles: FT-IR spectroscopy and fluorescence probe studies. Curr Opin Colloid Interface Sci 1(1):64–77.  https://doi.org/10.1016/s1359-0294(96)80046-x CrossRefGoogle Scholar
  84. 84.
    Mantsch HH, McElhaney RN (1991) Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy. Chem Phys Lipids 57(2–3):213–226.  https://doi.org/10.1016/0009-3084(91)90077-o CrossRefGoogle Scholar
  85. 85.
    Sung W, Kim D, Shen YR (2013) Sum-frequency vibrational spectroscopic studies of Langmuir monolayers. Curr Appl Phys 13(4):619–632.  https://doi.org/10.1016/j.cap.2012.12.002 CrossRefGoogle Scholar
  86. 86.
    Nihonyanagi S, Yamaguchi S, Tahara T (2017) Ultrafast dynamics at water interfaces studied by vibrational sum frequency generation spectroscopy. Chem Rev 117(16):10665–10693.  https://doi.org/10.1021/acs.chemrev.6b00728 CrossRefGoogle Scholar
  87. 87.
    Chung C-Y, Potma EO (2013) Biomolecular imaging with coherent nonlinear vibrational microscopy. Annu Rev Phys Chem 64(1):77–99.  https://doi.org/10.1146/annurev-physchem-040412-110103 CrossRefGoogle Scholar
  88. 88.
    Jubb AM, Hua W, Allen HC (2012) Environmental chemistry at vapor/water interfaces: insights from vibrational sum frequency generation spectroscopy. Annu Rev Phys Chem 63(1):107–130.  https://doi.org/10.1146/annurev-physchem-032511-143811 CrossRefGoogle Scholar
  89. 89.
    Sovago M, Vartiainen E, Bonn M (2009) Observation of buried water molecules in phospholipid membranes by surface sum-frequency generation spectroscopy. J Chem Phys 131(16):161107.  https://doi.org/10.1063/1.3257600 CrossRefGoogle Scholar
  90. 90.
    Sovago M, Vartiainen E, Bonn M (2010) Erratum: “Observation of buried water molecules in phospholipid membranes by surface sum-frequency generation spectroscopy”. [J Chem Phys 131, 161107 (2009)]. J Chem Phys 133(22):229901.  https://doi.org/10.1063/1.3511705 CrossRefGoogle Scholar
  91. 91.
    Feng R-J, Li X, Zhang Z, Lu Z, Guo Y (2016) Spectral assignment and orientational analysis in a vibrational sum frequency generation study of DPPC monolayers at the air/water interface. J Chem Phys 145(24):244707.  https://doi.org/10.1063/1.4972564 CrossRefGoogle Scholar
  92. 92.
    Chen X, Hua W, Huang Z, Allen HC (2010) Interfacial water structure associated with phospholipid membranes studied by phase-sensitive vibrational sum frequency generation spectroscopy. J Am Chem Soc 132(32):11336–11342.  https://doi.org/10.1021/ja1048237 CrossRefGoogle Scholar
  93. 93.
    Ma G, Allen HC (2006) DPPC Langmuir monolayer at the air–water interface: probing the tail and head groups by vibrational sum frequency generation spectroscopy. Langmuir 22(12):5341–5349.  https://doi.org/10.1021/la0535227 CrossRefGoogle Scholar
  94. 94.
    Hadicke A, Blume A (2013) Interactions of Pluronic block copolymers with lipid monolayers studied by epi-fluorescence microscopy and by adsorption experiments. J Colloid Interface Sci 407(327–338):327–338.  https://doi.org/10.1016/j.jcis.2013.06.041 CrossRefGoogle Scholar
  95. 95.
    Amado E, Kerth A, Blume A, Kressler J (2009) Phospholipid crystalline clusters induced by adsorption of novel amphiphilic triblock copolymers to monolayers. Soft Matter 5(3):669–675. doi: https://doi.org/10.1039/B813994f Google Scholar
  96. 96.
    Arouri A, Kerth A, Dathe M, Blume A (2011) The binding of an amphipathic peptide to lipid monolayers at the air/water interface is modulated by the lipid headgroup structure. Langmuir 27(6):2811–2818.  https://doi.org/10.1021/la104887s CrossRefGoogle Scholar
  97. 97.
    Erbe A, Kerth A, Dathe M, Blume A (2009) Interactions of KLA amphipathic model peptides with lipid monolayers. Chem Bio Chem 10(18):2884–2892.  https://doi.org/10.1002/cbic.200900444 CrossRefGoogle Scholar
  98. 98.
    Hadicke A, Blume A (2015) Binding of short cationic peptides (KX)4K to negatively charged DPPG monolayers: competition between electrostatic and hydrophobic interactions. Langmuir 31(44):12203–12214.  https://doi.org/10.1021/acs.langmuir.5b02882 CrossRefGoogle Scholar
  99. 99.
    Hadicke A, Blume A (2016) Binding of the cationic peptide (KL)4K to lipid monolayers at the air-water interface: effect of lipid headgroup charge, acyl chain length, and acyl chain saturation. J Phys Chem B 120(16):3880–3887.  https://doi.org/10.1021/acs.jpcb.6b01558 CrossRefGoogle Scholar
  100. 100.
    Brehmer T, Kerth A, Graubner W, Malesevic M, Hou B, Bruser T, Blume A (2012) Negatively charged phospholipids trigger the interaction of a bacterial tat substrate precursor protein with lipid monolayers. Langmuir 28(7):3534–3541.  https://doi.org/10.1021/la204473t CrossRefGoogle Scholar
  101. 101.
    Kerth A, Garidel P, Howe J, Alexander C, Mach J-P, Waelli T, Blume A, Rietschel ETh, Brandenburg K (2009) an infrared reflection–absorption spectroscopic (IRRAS) study of the interaction of Lipid A and lipopolysaccharide re with endotoxin-binding proteins. Med Chem 5(6):535–542.  https://doi.org/10.2174/157340609790170452 CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Chemistry–Physical ChemistryMartin-Luther-University Halle-WittenbergHalle(Saale)Germany

Personalised recommendations