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An Overview of Sex and Gender Considerations in Sleep and Alcohol Use

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Abstract

Purpose of Review

This paper explored the under-researched bidirectional alcohol/sleep link, examining sex and gender’s impact on this relationship and treatment.

Recent Findings

Although men have traditionally shown higher alcohol use than women, this gap is narrowing. Regarding sleep disorders, women are more likely to have insomnia and men are more likely to have obstructive sleep apnea. Alcohol is more likely to impact self-reported insomnia symptoms in women (sleep onset latency, daytime dysfunction) and sleep duration, fragmentation, and sleep architecture in men. Sex and gender differences may depend on age, sex hormones, and alcohol/sleep disorder severity. Women are more likely to seek insomnia treatment and engage in behavior changes, but less alcohol treatment than men.

Summary

Biological (sex) and psychosocial (gender) factors affect alcohol’s impact on sleep (and vice versa) and treatment seeking. Adopting a sex and gender lens-based framework is a high priority for comprehensive alcohol and sleep health research and clinical care.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. •• Chaudhary NS, Wong MM, Kolla BP, Kampman KM, Chakravorty S. The relationship between insomnia and the intensity of drinking in treatment-seeking individuals with alcohol dependence. Drug Alcohol Depend. 2020;215:108189. [Shows the high prevalence of insomnia disorder in patients with AUD]

    Article  PubMed  PubMed Central  Google Scholar 

  2. •• Pasman JA, Smit DJ, Kingma L, Vink JM, Treur JL, Verweij KJ. Causal relationships between substance use and insomnia. Drug Alcohol Depend. 2020;214:108151. [Prospective study showing insomnia symptoms predicting future heavy drinking and alcohol-related problems]

    Article  CAS  PubMed  Google Scholar 

  3. Short NA, Allan NP, Oglesby ME, Moradi S, Schmidt NB, Stecker T. Prospective associations between insomnia symptoms and alcohol use problems among former and current military service personnel. Drug Alcohol Depend. 2019;199:35–41.

    Article  PubMed  Google Scholar 

  4. Association AP. Diagnostic and statistical manual of mental disorders. (DSM-5®): American Psychiatric Pub; 2013.

    Book  Google Scholar 

  5. Dolsen EA, Harvey AG. Life-time history of insomnia and hypersomnia symptoms as correlates of alcohol, cocaine and heroin use and relapse among adults seeking substance use treatment in the United States from 1991 to 1994. Addiction. 2017;112(6):1104–11.

    Article  PubMed  PubMed Central  Google Scholar 

  6. •• Koob GF, Colrain IM. Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework. Neuropsychopharmacology. 2020;45(1):141–65. [Discusses high prevalence of AUD in patients with sleep disorders]

    Article  PubMed  Google Scholar 

  7. He S, Hasler BP, Chakravorty S. Alcohol and sleep-related problems. Curr Opin Psychol. 2019;30:117–22.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Brooks AT, Krumlauf M, Beck KH, Fryer CS, Yang L, Ramchandani VA, et al. A mixed methods examination of sleep throughout the alcohol recovery process grounded in the social cognitive theory: the role of self-efficacy and craving. Health Educ Behav. 2019;46(1):126–36.

    Article  PubMed  Google Scholar 

  9. Jager J, Keyes KM, Son D, Kloska DD, Patrick ME, Schulenberg JE. Cohort and age trends in age 35-45 prevalence of alcohol use disorder symptomology, by severity, race, and education. Drug Alcohol Depend. 2021;226:1–10.

    Article  Google Scholar 

  10. Agabio R, Pisanu C, Luigi Gessa G, Franconi F. Sex differences in alcohol use disorder. Curr Med Chem. 2017;24(24):2661–70.

    Article  CAS  PubMed  Google Scholar 

  11. •• Kocevska D, Lysen TS, Dotinga A, Koopman-Verhoeff ME, Luijk MPCM, Antypa N, et al. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis. Nat Hum Behav. 2021;5:113–22. [Meta-analysis showing higher rates of alcohol use, heavy drinking and AUD in men compared to women]

    Article  PubMed  Google Scholar 

  12. Ford ES, Cunningham TJ, Giles WH, Croft JB. Trends in insomnia and excessive daytime sleepiness among US adults from 2002 to 2012. Sleep Med. 2015;16:372–8.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Zhabenko N, Wojnar M, Brower KJ. Prevalence and correlates of insomnia in a Polish sample of alcohol-dependent patients. Alcohol Clin Exp Res. 2012;36(9):1600–7.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Haario P, Rahkonen O, Laaksonen M, Lahelma E, Lallukka T. Bidirectional associations between insomnia symptoms and unhealthy behaviours. J Sleep Res. 2013;22(1):89–95.

    Article  PubMed  Google Scholar 

  15. Brower KJ. Assessment and treatment of insomnia in adult patients with alcohol use disorders. Alcohol. 2015;49(4):417–27.

    Article  PubMed  Google Scholar 

  16. Breslau N, Roth T, Rosenthal L, Andreski P. Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults. Biol Psychiatry. 1996;39(6):411–8.

    Article  CAS  PubMed  Google Scholar 

  17. Fortuna LR, Cook B, Porche MV, Wang Y, Amaris AM, Alegria M. Sleep disturbance as a predictor of time to drug and alcohol use treatment in primary care. Sleep Med. 2018;42:31–7.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Aldrich MS, Brower KJ, Hall JM. Sleep-disordered breathing in alcoholics. Alcohol Clin Exp Res. 1999;23(1):134–40.

    Article  CAS  PubMed  Google Scholar 

  19. Baldassarri SR, Chu J-h, Deng A, Xu Z, Blohowiak RF, Byrne S, et al. Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea. Sleep Breath. 2023;27:2479–90.

  20. Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders: an opportunity for prevention? Jama. 1989;262(11):1479–84.

    Article  CAS  PubMed  Google Scholar 

  21. Aernout E, Benradia I, Hazo J-B, Sy A, Askevis-Leherpeux F, Sebbane D, et al. International study of the prevalence and factors associated with insomnia in the general population. Sleep Med. 2021;82:186–92.

    Article  PubMed  Google Scholar 

  22. Hasler BP, Pedersen SL. Sleep and circadian risk factors for alcohol problems: a brief overview and proposed mechanisms. Curr Opin Psychol. 2020;34:57–62.

    Article  PubMed  Google Scholar 

  23. Brower KJ, Aldrich MS, Robinson EA, Zucker RA, Greden JF. Insomnia, self-medication, and relapse to alcoholism. Am J Psychiatr. 2001;158(3):399–404.

    Article  CAS  PubMed  Google Scholar 

  24. •• Schweizer CA, Hoggatt KJ, Washington DL, Bean-Mayberry B, Yano EM, Mitchell MN, et al. Use of alcohol as a sleep aid, unhealthy drinking behaviors, and sleeping pill use among women veterans. Sleep Health. 2019;5(5):495–500. [Discusses the prevalence of alcohol use as a sleep aid]

    Article  PubMed  PubMed Central  Google Scholar 

  25. Goodhines PA, Gellis LA, Kim J, Fucito LM, Park A. Self-medication for sleep in college students: concurrent and prospective associations with sleep and alcohol behavior. Behav Sleep Med. 2019;17(3):327–41.

    Article  PubMed  Google Scholar 

  26. Roehrs T, Roth T. Insomnia as a path to alcoholism: tolerance development and dose escalation. Sleep. 2018;41(8):zsy091.

  27. Brower KJ. Insomnia, alcoholism and relapse. Sleep Med Rev. 2003;7(6):523–39.

    Article  PubMed  Google Scholar 

  28. • Graupensperger S, Fairlie AM, Vitiello MV, Kilmer JR, Larimer ME, Patrick ME, et al. Daily-level effects of alcohol, marijuana, and simultaneous use on young adults’ perceived sleep health. Sleep. 2021;44(12):zsab187. [Within-person analysis showing daily impact of alcohol use on same night sleep health]

    Article  PubMed  PubMed Central  Google Scholar 

  29. Miller MB, Freeman LK, Deroche CB, Park CJ, Hall NA, McCrae CS. Sleep and alcohol use among young adult drinkers with Insomnia: a daily process model. Addict Behav. 2021;119:106911.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Miller MB, Chan WS, Boissoneault J, Robinson M, Staud R, Berry RB, et al. Dynamic daily associations between insomnia symptoms and alcohol use in adults with chronic pain. J. Sleep Res. 2018;27(3):e12604.

    Article  PubMed  Google Scholar 

  31. Simou E, Britton J, Leonardi-Bee J. Alcohol and the risk of sleep apnoea: a systematic review and meta-analysis. Sleep Med. 2018;42:38–46.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Huang Y-P, Chien W-C, Chung C-H, Huang Y-C, Kuo S-C, Chen C-Y, et al. Increased incidence of alcohol use disorder and alcohol-related psychiatric disorders in patients with obstructive sleep apnea: a nationwide population-based cohort study. Sleep Med. 2023;101:197–204.

    Article  PubMed  Google Scholar 

  33. Yang S, Guo X, Liu W, Li Y, Liu Y. Alcohol as an independent risk factor for obstructive sleep apnea. Ir J Med Sci. 2022;191(3):1325–30.

    Article  CAS  PubMed  Google Scholar 

  34. Hasler BP, Franzen PL, de Zambotti M, Prouty D, Brown SA, Tapert SF, et al. Eveningness and later sleep timing are associated with greater risk for alcohol and marijuana use in adolescence: initial findings from the national consortium on alcohol and neurodevelopment in adolescence study. Alcohol Clin Exp Res. 2017;41(6):1154–65.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Hasler BP, Graves JL, Wallace ML, Claudatos S, Franzen PL, Nooner KB, et al. Self-reported sleep and circadian characteristics predict alcohol and cannabis use: a longitudinal analysis of the National Consortium on Alcohol and Neurodevelopment in Adolescence Study. Alcohol Clin Exp Res. 2022;46(5):848–60.

    Article  PubMed  PubMed Central  Google Scholar 

  36. • Patrick ME, Terry-mcElrath YM, Miech RA, Schulenberg JE, O'Malley PM, Johnston LD. Age-specific prevalence of binge and high-intensity drinking among U.S. young adults: changes from 2005 to 2015. Alcohol Clin Exp. Res. 2017;41:1319–28. [Found women more likely than men to have health-related consequences from alcohol use]

    Article  PubMed  PubMed Central  Google Scholar 

  37. Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, et al. Epidemiology of DSM-5 alcohol use disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry. 2015;72:757–66.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, et al. Epidemiology of DSM-5 alcohol use disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry. 2015;72(8):757–66.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Peltier MR, Verplaetse TL, Mineur YS, Petrakis IL, Cosgrove KP, Picciotto MR, et al. Sex differences in stress-related alcohol use. Neurobiology of Stress. 2019;10:100149.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Abuse S. Mental Health Services Administration (SAMHSA). In: 2012 National Survey on Drug Use and Health (NSDUH). S Prepared by Office of Applied Studies (OAS), and by RTI International (RTI International is a trade name of Research Triangle Institute). Rockville, MD: Substance Abuse and Mental Health Services Administration; 2020.

    Google Scholar 

  41. Blume SB. Women and alcohol: A review. Jama. 1986;256(11):1467–70.

    Article  CAS  PubMed  Google Scholar 

  42. Pöschl G, Seitz HK. Alcohol and cancer. Alcohol Alcohol. 2004;39(3):155–65.

    Article  PubMed  Google Scholar 

  43. Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, et al. Alcohol consumption and the risk of morbidity and mortality for different stroke types-a systematic review and meta-analysis. BMC Public Health. 2010;10(1):1–12.

    Article  Google Scholar 

  44. Patrick ME, Terry-McElrath YM, Evans-Polce RJ, Schulenberg JE. Negative alcohol-related consequences experienced by young adults in the past 12 months: Differences by college attendance, living situation, binge drinking, and sex. Addict Behav. 2020;105:106320.

  45. Martel MM, Eisenlohr-Moul T, Roberts B. Interactive effects of ovarian steroid hormones on alcohol use and binge drinking across the menstrual cycle. J Abnorm Psychol. 2017;126(8):1104.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Emanuele MA, Wezeman F, Emanuele NV. Alcohol’s effects on female reproductive function. Alcohol Res Health. 2002;26(4):274.

    PubMed  PubMed Central  Google Scholar 

  47. Erol A, Ho AMC, Winham SJ, Karpyak VM. Sex hormones in alcohol consumption: a systematic review of evidence. Addict Biol. 2019;24(2):157–69.

    Article  CAS  PubMed  Google Scholar 

  48. Nolen-Hoeksema S, Hilt L. Possible contributors to the gender differences in alcohol use and problems. J Gen Psychol. 2006;133(4):357–74.

    Article  PubMed  Google Scholar 

  49. Frezza M, Di Padova C, Pozzato G, Terpin M, Baraona E, Lieber CS. High blood alcohol levels in women. N Engl J Med. 1990;322(2):95–9.

    Article  CAS  PubMed  Google Scholar 

  50. Ohayon MM. Epidemiological overview of sleep disorders in the general population. Sleep Med Res. 2011;2:1–9.

    Article  Google Scholar 

  51. Zhang B, Wing Y-K. Sex differences in insomnia: a meta-analysis. Sleep. 2006;29(1):85–93.

    Article  PubMed  Google Scholar 

  52. Drake CL, Friedman NP, Wright Jr KP, Roth T. Sleep reactivity and insomnia: genetic and environmental influences. Sleep. 2011;34(9):1179–88.

  53. Mong JA, Baker FC, Mahoney MM, Paul KN, Schwartz MD, Semba K, et al. Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormones. J. Neurosci. 2011;31(45):16107–16.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  54. Mong JA, Cusmano DM. Sex differences in sleep: impact of biological sex and sex steroids. Philos Trans R Soc Lond B: Biol Sci. 2016;371(1688):20150110.

    Article  PubMed  Google Scholar 

  55. McKinney J, Ortiz-Young D, Jefferson F. Gender differences in obstructive sleep apnea and the associated public health burden. Sleep Biol Rhythms. 2015;13:196–209.

    Article  Google Scholar 

  56. Roehrs T, Kapke A, Roth T, Breslau N. Sex differences in the polysomnographic sleep of young adults: a community-based sample. Sleep Med. 2006;7:49–53.

    Article  PubMed  Google Scholar 

  57. •• Sidani S, Guruge S, Fox M, Collins L. Gender differences in perpetuating factors, experience and management of chronic insomnia. J gender stud. 2019;28(4):402–13. Shows men more likely to experience dysfunctional beliefs and nap, whereas women more likely to have cognitive arousal, worse insomnia severity, and utilize self-management strategies.

    Article  Google Scholar 

  58. • Huitron-Resendiz S, Nadav T, Krause S, Cates-Gatoo C, Polis I, Roberts AJ. Effects of withdrawal from chronic intermittent ethanol exposure on sleep characteristics of female and male mice. Alcohol Clin Exp Res. 2018;42:540–50. [Preclinical study showing sex differences in objective sleep-related consequences of alcohol administration.]

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Roehrs T, Roth T. Sleep, sleepiness, sleep disorders, and alcohol use and abuse. Sleep Med Rev. 2001;5:287–97.

    Article  PubMed  Google Scholar 

  60. Theorell-Haglow J, Miller CB, Bartlett DJ, Yee BJ, Openshaw HD, Grunstein RR. Gender differences in obstructive sleep apnea, insomnia, and restless legs syndrome in adults - What do we know? A clinical update. Sleep Med Rev. 2018;38:28–38.

    Article  PubMed  Google Scholar 

  61. Baker FC, Carskadon MA, Hasler BP. Sleep and women's health: sex-and age-specific contributors to alcohol use disorders. J Women's Health. 2020;29(3):443–5.

  62. Verlinden JJ, Moloney ME, Whitehurst LN, Weafer J. Sex differences in the association between poor sleep quality and alcohol-related problems among heavy drinkers with insomnia. Front Behavior Neurosci. 2022;16:875168.

  63. Zhang R, Wiers CE, Manza P, Tomasi D, Shokri-Kojori E, Kerich M, et al. Severity of alcohol use disorder influences sex differences in sleep, mood, and brain functional connectivity impairments. Brain Comm. 2022:4.

  64. Guo Y, Hu H, Liu Y, Leng Y, Gao X, Cui Q, et al. Gender differences in the relationship between alcohol consumption and insomnia in the northern Chinese population. PLoS One. 2018;13:e0207392.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  65. Freeman LK, Miller MB, Simenson A, Sparrow E, Costa AN, Musich M, et al. Sex differences in associations between alcohol use and sleep in mid-to-late life. Sleep Med. 2022;100:298–303.

    Article  PubMed  Google Scholar 

  66. Colrain IM, Turlington S, Baker FC. Impact of alcoholism on sleep architecture and EEG power spectra in men and women. Sleep. 2009;32:1341–52.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Arnedt JT, Rohsenow DJ, Almeida AB, Hunt SK, Gokhale M, Gottlieb DJ, et al. Sleep following alcohol intoxication in healthy young adults: effects of sex and family history of alcoholism. Alcohol Clin Exp Res. 2011;35:870–8.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Britton A, Fat LN, Neligan A. The association between alcohol consumption and sleep disorders among older people in the general population. Sci Rep. 2020;10(1):5275.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Park S-Y, Oh M-K, Lee B-S, Kim H-G, Lee W-J, Lee J-H, et al. The effects of alcohol on quality of sleep. Korean J Fam Med. 2015;36(6):294.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Zhang R, Wiers CE, Manza P, Tomasi D, Shokri-Kojori E, Kerich M, Almira E, Schwandt M, Diazgranados N, Momenan R, Volkow ND. Severity of alcohol use disorder influences sex differences in sleep, mood, and brain functional connectivity impairments. Brain Communicat. 2022;4(4):fcac127.

  71. Nolen-Hoeksema S, Hilt L. Possible contributors to the gender differences in alcohol use and problems. J Gen Psychol. 2006;133(4):357–74.

    Article  PubMed  Google Scholar 

  72. Taylor DJ, Bramoweth AD. Patterns and consequences of inadequate sleep in college students: substance use and motor vehicle accidents. J Adolesc Health. 2010;46(6):610–2.

    Article  PubMed  Google Scholar 

  73. Roehrs T, Hollebeek E, Drake C, Roth T. Substance use for insomnia in Metropolitan Detroit. J Psychosom Res. 2002;53(1):571–6.

    Article  PubMed  Google Scholar 

  74. Lam T, Ogeil RP, Allsop S, Chikritzhs T, Fischer J, Midford R, et al. Insomnia and regulation of sleep-wake cycle with drugs among adolescent risky drinkers. J Clin Sleep Med. 2018;14(9):1529–37.

    Article  PubMed  PubMed Central  Google Scholar 

  75. Jaussent I, Dauvilliers Y, Ancelin M-L, Dartigues J-F, Tavernier B, Touchon J, et al. Insomnia symptoms in older adults: associated factors and gender differences. Am J Geriatr Psychiatry. 2011;19(1):88–97.

    Article  PubMed  PubMed Central  Google Scholar 

  76. Venn S, Meadows R, Arber S. Gender differences in approaches to self-management of poor sleep in later life. Soc Sci Med. 2013;79:117–23.

    Article  PubMed  Google Scholar 

  77. Rognmo K, Bergvik S, Rosenvinge JH, Bratlid KL, Friborg O. Gender differences in the bidirectional relationship between alcohol consumption and sleeplessness: the Tromsø study. BMC Public Health. 2019;19(1):1–8.

    Article  Google Scholar 

  78. Chakravorty S, Chaudhary NS, Brower KJ. Alcohol dependence and its relationship with insomnia and other sleep disorders. Alcohol Clin Exp Res. 2016;40:2271–82.

    Article  PubMed  PubMed Central  Google Scholar 

  79. Miller MB, Donahue ML, Carey KB, Scott-Sheldon LAJ. Insomnia treatment in the context of alcohol use disorder: a systematic review and meta-analysis. Drug Alcohol Depend. 2017;181:200–7.

    Article  PubMed  PubMed Central  Google Scholar 

  80. Chakravorty S, Morales KH, Arnedt JT, Perlis ML, Oslin DW, Findley JC, et al. Cognitive behavioral therapy for insomnia in alcohol-dependent veterans: a randomized, controlled pilot study. Alcohol Clin Exp Res. 2019;43:1244–53.

    Article  PubMed  PubMed Central  Google Scholar 

  81. Miller MB, Carpenter RW, Freeman LK, Dunsiger S, McGeary JE, Borsari B, McCrae CS, Arnedt JT, Korte P, Merrill JE, Carey KB. Effect of cognitive behavioral therapy for insomnia on alcohol treatment outcomes among US veterans: a randomized clinical trial. JAMA Psychiatry. 2023;80(9):905–13.

  82. Fucito LM, DeMartini KS, Hanrahan TH, Yaggi HK, Heffern C, Redeker NS. Using sleep interventions to engage and treat heavy-drinking college students: A randomized pilot study. Alcohol Clin Exp Res. 2017;41(4):798–809.

  83. Miller MB, Deroche CB, Freeman LK, Park CJ, Hall NA, Sahota PK, et al. Cognitive Behavioral Therapy for Insomnia among young adults who are actively drinking: a randomized pilot trial. Sleep. 2021;44:1–11.

    Article  Google Scholar 

  84. James E, Freund M, Booth A, Duncan MJ, Johnson N, Short CE, et al. Comparative efficacy of simultaneous versus sequential multiple health behavior change interventions among adults: a systematic review of randomised trials. Prev Med. 2016;89:211–23.

    Article  PubMed  Google Scholar 

  85. Lilienfeld SO, Ritschel LA, Lynn SJ, Cautin RL, Latzman RD. Why many clinical psychologists are resistant to evidence-based practice: root causes and constructive remedies. Clin Psychol Rev. 2013;33(7):883–900.

    Article  PubMed  Google Scholar 

  86. Gilbert PA, Pro G, Zemore SE, Mulia N, Brown G. Gender differences in use of alcohol treatment services and reasons for nonuse in a national sample. Alcohol Clin Exp Res. 2019;43:722–31.

    Article  PubMed  PubMed Central  Google Scholar 

  87. Greenfield SF, Brooks AJ, Gordon SM, Green CA, Kropp F, McHugh RK, et al. Substance abuse treatment entry, retention, and outcome in women: a review of the literature. Drug Alcohol Depend. 2007;86(1):1–21.

    Article  PubMed  Google Scholar 

  88. Chen JA, Glass JE, Bensley KM, Goldberg SB, Lehavot K, Williams EC. Racial/ethnic and gender differences in receipt of brief intervention among patients with unhealthy alcohol use in the US Veterans Health Administration. J Subs Abuse Treat. 2020;119:108078. [Showed that gender differences in brief alcohol intervention outcomes vary by race.]

  89. Williams EC, Lapham GT, Rubinsky AD, Chavez LJ, Berger D, Bradley KA. Influence of a targeted performance measure for brief intervention on gender differences in receipt of brief intervention among patients with unhealthy alcohol use in the Veterans Health Administration. J Subst Abus Treat. 2017;81:11–6.

    Article  Google Scholar 

  90. Agabio R, Pani PP, Preti A, Gessa GL, Franconi F. Efficacy of medications approved for the treatment of alcohol dependence and alcohol withdrawal syndrome in female patients: a descriptive review. Eur Addict Res. 2016;22(1):1–16.

    Article  PubMed  Google Scholar 

  91. Carey KB, Scott-Sheldon LA, Elliott JC, Garey L, Carey MP. Face-to-face versus computer-delivered alcohol interventions for college drinkers: a meta-analytic review, 1998 to 2010. Clin Psychol Rev. 2012;32(8):690–703.

    Article  PubMed  PubMed Central  Google Scholar 

  92. • Livingston NA, Simpson T, Lehavot K, Ameral V, Brief DJ, Enggasser JL, et al. Differential alcohol treatment response by gender following use of VetChange. Drug Alcohol Depend. 2021;221:108552. [Showed women use online alcohol use interventions at proportionately higher rates than men, but show less benefit than men in terms of drinking reduction.]

    Article  PubMed  Google Scholar 

  93. Group PMR. Matching alcoholism treatments to client heterogeneity: Project MATCH three-year drinking outcomes. Alcohol Clin Exp Res. 1998;22(6):1300–11.

    Google Scholar 

  94. Kelly JF, Hoeppner BB. Does Alcoholics Anonymous work differently for men and women? A moderated multiple-mediation analysis in a large clinical sample. Drug Alcohol Depend. 2013;130(1):186–93.

    Article  PubMed  Google Scholar 

  95. • Niv N, Hser Y-I. Women-only and mixed-gender drug abuse treatment programs: service needs, utilization and outcomes. Drug Alcohol Depend. 2007;87(2-3):194–201. [Not last 3 years – but showed the importance of tailoring alcohol use disorder programs for women]

    Article  PubMed  Google Scholar 

  96. Liu Y, Zhang J, Lam SP, Yu MWM, Li SX, Zhou J, et al. Help-seeking behaviors for insomnia in Hong Kong Chinese: a community-based study. Sleep Med. 2016;21:106–13.

    Article  PubMed  Google Scholar 

  97. •• Morin CM, LeBlanc M, Daley M, Gregoire J, Merette C. Epidemiology of insomnia: prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors. Sleep med. 2006;7(2):123–30. [Not last years – but showed gender differences in insomnia help-seeking. Specifically, women were more likely than men to consult general practitioner, while men were more likely than women to consult specialists]

    Article  CAS  PubMed  Google Scholar 

  98. Suh S, Cho N, Zhang J. Sex differences in insomnia: from epidemiology and etiology to intervention. Curr Psychiatry Rep. 2018;20(9):1–12.

    Article  Google Scholar 

  99. Lami MJ, Martínez MP, Sánchez AI, Miró E, Diener FN, Prados G, et al. Gender differences in patients with fibromyalgia undergoing cognitive-behavioral therapy for insomnia: preliminary data. Pain Pract. 2016;16(2):E23–34.

    Article  PubMed  Google Scholar 

  100. Morin CM, Culbert JP, Schwartz SM. Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy. Am. J. Psychiatr. 2006;151(8):1172–80.

    Google Scholar 

  101. Greenblatt DJ, Harmatz JS, von Moltke LL, Wright CE, Durol ALB, Harrel-Joseph LM, et al. Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences. J Pharmacol Exp Ther. 2000;293(2):435–43.

    CAS  PubMed  Google Scholar 

  102. Farkas RH, Unger EF, Temple R. Zolpidem and driving impairment—identifying persons at risk. N Engl J Med. 2013;369(8):689–91.

    Article  CAS  PubMed  Google Scholar 

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Funding

No funding was obtained for this work. Investigator contributions to this project were supported by the National Institutes of Health (R01NR017168, R01NR017168S1, R01AG061976, PI: McCrae and Co-I: Curtis; R01DA050744, PI: McCrae and Co-Is Curtis and Miller; K23AA026895, PI: Miller), Department of Defense (DOD W81XWH2010399, PI: McCrae and Co-I: Curtis), and the University of Missouri (TRIUMPH Initiative Awards; PI: Curtis; PI: McCrae).

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A.F.C., M.B.M., A.N.C., and M.M. drafted the manuscript. A.F.C. created Figs. 1 and 2. A.F.C. and A.N.C. created Table 1. All authors reviewed the manuscript and figures.

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Correspondence to Ashley F. Curtis.

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Curtis, A.F., Miller, M.B., Costa, A.N. et al. An Overview of Sex and Gender Considerations in Sleep and Alcohol Use. Curr Addict Rep 11, 316–326 (2024). https://doi.org/10.1007/s40429-023-00539-7

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