Acknowledgement to Referees

Dear Reader,

As we reach the final issue of Drug Safety for 2018, we wish to reflect on another successful year’s achievements, and to thank all those who have contributed their time and effort to guarantee the high quality of our content.

2018 was a successful year for Drug Safety. Over 100 articles have been published; the most popular of these, in terms of downloads from SpringerLink as at September 2018, have been:

• EudraVigilance Medicines Safety Database: Accessible Data for Research and Public Health Protection. Rodrigo Postigo, Sabine Brosch, Jim Slattery, Anja van Haren, Jean-Michel Dogné, Xavier Kurz, Gianmario Candore, Francois Domergue, Peter Arlett

• Sorting Through the Safety Data Haystack: Using Machine Learning to Identify Individual Case Safety Reports in Social-Digital Media. Shaun Comfort, Sujan Perera, Zoe Hudson, Darren Dorrell, Shawman Meireis, Meenakshi Nagarajan, Cartic Ramakrishnan, Jennifer Fine

• What Future Healthcare Professionals Need to Know About Pharmacovigilance: Introduction of the WHO PV Core Curriculum for University Teaching with Focus on Clinical Aspects. Rike van Eekeren, Leàn Rolfes, Andries S. Koster, Lara Magro, Gurumurthy Parthasarathi, Hussain Al Ramimmy, Tim Schutte, Daisuke Tanaka, Eugène van Puijenbroek, Linda Härmark

• Potential Risks Related to Modulating Interleukin-13 and Interleukin-4 Signalling: A Systematic Review. Martin Braddock, Nicola A. Hanania, Amir Sharafkhaneh, Gene Colice, Mats Carlsson

• Evidence-Based Recommendations to Improve the Safe Use of Drugs in Patients with Liver Cirrhosis. Rianne A. Weersink, Margriet Bouma, David M. Burger, Joost P. H. Drenth, S. Froukje Harkes-Idzinga, Nicole G. M. Hunfeld, Herold J. Metselaar, Margje H. Monster-Simons, Katja Taxis, Sander D. Borgsteede

• Interest in a Mobile App for Two-Way Risk Communication: A Survey Study Among European Healthcare Professionals and Patients. Sieta T. de Vries, Petra Denig, Carmen Lasheras Ruiz, François Houÿez, Lisa Wong, Alastair Sutcliffe, Peter G. M. Mol, on behalf of IMI Web-RADR Work Package 3b Consortium

• Safety Communication Tools and Healthcare Professionals’ Awareness of Specific Drug Safety Issues in Europe: A Survey Study. Sieta T. de Vries, Maartje J. M. van der Sar, Anna Marie Coleman, Yvette Escudero, Alfonso Rodríguez Pascual, Miguel-Ángel Maciá Martínez, Amelia Cupelli, Ilaria Baldelli, Ivana Šipić, Adriana Andrić, Line Michan, Petra Denig, Peter G. M. Mol, on behalf of SCOPE work package 6

• Characteristics, Quality and Contribution to Signal Detection of Spontaneous Reports of Adverse Drug Reactions Via the WEB-RADR Mobile Application: A Descriptive Cross-Sectional Study. Ingrid Oosterhuis, Henric Taavola, Philip M. Tregunno, Petar Mas, Sara Gama, Victoria Newbould, Ola Caster, Linda Härmark

• The Impact of Biologics and Tofacitinib on Cardiovascular Risk Factors and Outcomes in Patients with Rheumatic Disease: A Systematic Literature Review. Michael Nurmohamed, Ernest Choy, Sadiq Lula, Blerina Kola, Ryan DeMasi, Paola Accossato

• Non-bleeding Adverse Events with the Use of Direct Oral Anticoagulants: A Sequence Symmetry Analysis. Géric Maura, Cécile Billionnet, Joël Coste, Alain Weill, Anke Neumann, Antoine Pariente

Social media sharing of information is becoming more important and is another metric with which to measure the reach of articles. This year the following articles published in Drug Safety scored highly on the Altmetric system:

• Sorting Through the Safety Data Haystack: Using Machine Learning to Identify Individual Case Safety Reports in Social-Digital Media. Shaun Comfort, Sujan Perera, Zoe Hudson, Darren Dorrell, Shawman Meireis, Meenakshi Nagarajan, Cartic Ramakrishnan, Jennifer Fine

• Amyotrophic Lateral Sclerosis Associated with Statin Use: A Disproportionality Analysis of the FDA’s Adverse Event Reporting System. Beatrice A. Golomb, Abril Verden, Alexis K. Messner, Hayley J. Koslik, Keith B. Hoffman

• Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database. Leticia Ortiz de Landaluce, Pere Carbonell, Carmen Asensio, Núria Escoda, Pilar López, Joan-Ramon Laporte

• Review of Case Narratives from Fatal Overdoses Associated with Injectable Naltrexone for Opioid Dependence. Roxanne Saucier, Daniel Wolfe, Nabarun Dasgupta

• Safety of Human Papillomavirus Vaccines: An Updated Review. Anastasia Phillips, Cyra Patel, Alexis Pillsbury, Julia Brotherton, Kristine Macartney

• What Future Healthcare Professionals Need to Know About Pharmacovigilance: Introduction of the WHO PV Core Curriculum for University Teaching with Focus on Clinical Aspects. Rike van Eekeren, Leàn Rolfes, Andries S. Koster, Lara Magro, Gurumurthy Parthasarathi, Hussain Al Ramimmy, Tim Schutte, Daisuke Tanaka, Eugène van Puijenbroek, Linda Härmark

• Prescription Opioid Fatalities: Examining Why the Healer Could be the Culprit. Adeleke D. Adewumi, Christine E. Staatz, Samantha A. Hollingworth, Jason P. Connor, Rosa Alati

• Non-bleeding Adverse Events with the Use of Direct Oral Anticoagulants: A Sequence Symmetry Analysis. Géric Maura, Cécile Billionnet, Joël Coste, Alain Weill, Anke Neumann, Antoine Pariente

• Assessment of the Utility of Social Media for Broad-Ranging Statistical Signal Detection in Pharmacovigilance: Results from the WEB-RADR Project. Ola Caster, Juergen Dietrich, Marie-Laure Kürzinger, Magnus Lerch, Simon Maskell, G. Niklas Norén, Stéphanie Tcherny-Lessenot, Benoit Vroman, Antoni Wisniewski, John van Stekelenborg

• Comparative Rates of Mortality and Serious Adverse Effects Among Commonly Prescribed Opioid Analgesics. David L. Murphy, Jacob A. Lebin, Stevan G. Severtson, Heather A. Olsen, Nabarun Dasgupta, Richard C. Dart

The quality of articles published in the journal is also reflected in its most recent impact factor (3.643). The journal is in Quartile 1 of all three JCR categories it is ranked in, namely Public Environmental & Occupational Health, Pharmacology & Pharmacy, and Toxicology.

Other journals in the Adis Premier Journals Portfolio (http://www.springer.com/gp/adis) continue to prosper with substantial increases in usage. In addition, this year has seen Applied Health Economics and Health Policy receive its first impact factor.

We thank the authors who have contributed articles to Drug Safety over the course of 2018. The skill and dedication of all authors are critical to the continued publication of the journal. The quality of published articles is also testament to the significant efforts of the peer reviewers, whose commitment ensures that the journal’s content is held to the highest possible standard. We would like to thank the following individuals who acted as reviewers for Drug Safety in the last 12 months:

Piotr Adamski, Poland

Elizabeth N. Allen, South Africa

Susan E. Andrade, USA

Andrea Angheben, Italy

Peter Arlett, UK

Mickael Arnaud, France

Jeffrey K. Aronson, UK

Sandrine Aspeslagh, Belgium

Haleh Bagheri, France

Jane P. Bai, USA

Brian A. Baldo, Australia

Juan M. Banda, USA

Andrew Bate, UK

Bernard Begaud, France

Justine Benevent, France

Paul Beninger, USA

Margaret Bermingham, Ireland

Caryn Bern, USA

Delphine Bertram, The Netherlands

Elise Bigeard, France

Ingrid A. Binswanger, USA

Steven T. Bird, USA

Einar S. Björnsson, Sweden

Michael Bodmer, Switzerland

Anna Bonjoch, Spain

Cedric Bousquet, France

Ian W. Boyd, Australia

Klaus Bühler, Germany

Zachary Burningham, USA

Katsiaryna Bykov, USA

Cathal A. Cadogan, Ireland

Rose Cairns, Australia

Gianmario Candore, UK

Dolors D. Capella, Spain

Alfonso Carvajal, Spain

Ola Caster, Sweden

Mario Cazzola, Italy

Rebecca E. Chandler, Sweden

Qingyu Chen, USA

Teng-Chou Chen, UK

Ching-Lung Cheung, Hong Kong

Paul Chin, New Zealand

Imti Choonara, UK

Jacqueline Cloos, The Netherlands

Mike Conway, USA

Anthony R. Cox, UK

Giuseppe Curigliano, Italy

Paola M. Cutroneo, Italy

Gerald J. Dal Pan, USA

Gaby Danan, France

Carl D’Arcy, Canada

Borje Darpo, Sweden

Nabarun Dasgupta, USA

Fabrizio De Ponti, Italy

Sieta T. De Vries, The Netherlands

T. W. De Vries, The Netherlands

Lucio Dell’Atti, Italy

Stephanie Dellicour, UK

Roni P. Dodiuk-Gad, Israel

Nancy A. Dreyer, USA

Mei Sheng Duh, USA

Jon Duke, USA

Adam Dunn, Australia

Brian D. Edwards, UK

Moses S. Elisaf, Greece

Dean Elterman, Canada

Luis F. Ensina, Brazil

Martin Faehling, Germany

James A. Feinstein, USA

Georg Ferber, Switzerland

Robin E. Ferner, UK

Carmen Ferrajolo, Italy

Daniel Fife, USA

Robert J. Fontana, USA

Daniel E. Freedberg, USA

Gerrit Frommeyer, Germany

Massimo Gadina, USA

Sara Garfield, UK

Thijs J. Giezen, The Netherlands

Rosa Gini, Italy

Su Golder, UK

Graciela Gonzalez, USA

David J. Graham, USA

Shelly L. Gray, USA

Elena Grebenciucova, USA

Robert Güerri-Fernández, Spain

Martin C. Gulliford, UK

Shashank Gupta, India

Kelly G. Gwathmey, USA

Maryam Habibi, Germany

Guido Haenen, The Netherlands

Britta Haenisch, Germany

Eelko Hak, The Netherlands

Richard A. Hansen, USA

Linda Härmark, The Netherlands

Rave Harpaz, USA

Abraham Hartzema, USA

Manfred Hauben, USA

Daniel B. Hawcutt, UK

David A. Henry, Australia

Joanne M.-W. Ho, Canada

Keith B. Hoffman, USA

Antoine Hollebecque, France

Michael R. Horsman, Denmark

Yi-Shin Huang, Taiwan, Republic of China

Jennifer Humphreys, UK

Christine M. Hunt, USA

Patrick Imfeld, Switzerland

Pedro Inacio, Finland

Ambrose O. Isah, Nigeria

Geer M. Ishaq, India

Sergey Ivanov, The Russian Federation

Abhyuday Jagannatha, USA

Catherine B. Johannes, USA

Juergen John, Germany

Sue Jordan, UK

Vivekanandan Kalaiselvan, India

Lisa Kalisch Ellett, Australia

Yea-Huei Kao Yang, Taiwan, Republic of China

Chris Karapetis, Australia

Richard N. Keers, UK

Brigitte Keller-Stanislawski, Germany

Erin Kelty, Australia

Debra Kennedy, Australia

Ganessan Kichenadasse, Australia

Kevin Klein, The Netherlands

Anthony Kong, UK

Vassilis Koutkias, Greece

Janet Krska, UK

Kongkiat Kulkantrakorn, Thailand

Maryse Lapeyre-Mestre, France

Anne M. Larson, USA

Volker Lauschke, Sweden

Erica Lazarus, South Africa

Bénédicte Lebrun-Vignes, France

William M. Lee, USA

Andreia Leite, UK

Roberto Leone, Italy

Feifan Liu, USA

Maria Loane, UK

Zhiyong Lu, USA

Solomon J. Lubinga, USA

Yuan Luo, USA

Thomas T. M. Macdonald, UK

Miguel-Angel Macia-Martinez, Spain

Malcolm Maclure, Canada

Francois Maignen, UK

Aukje K. Mantel-Teeuwisse, The Netherlands

Judith C. Maro, USA

Naoya Masumori, Japan

Deirdre Mccarthy, USA

Lauren Mccormack, USA

John Mcewen, Australia

Andreas D. Meid, Germany

Mohammad Junaid M. H. Memon, USA

Helmout Modjtahedi, UK

Dennis G. Moledina, USA

Mathias Møllebæk, Denmark

Thomas J. Moore, USA

Ugo Moretti, Italy

Elaine H. Morrato, USA

Andrew Mosholder, USA

Julie Mouchet, France

Mehdi Najafzadeh, USA

Victoria Newbould, UK

Marc C. Nicklaus, USA

Ole Haagen Nielsen, Denmark

Sten Olsson, Sweden

Ingrid Oosterhuis, The Netherlands

Vicki Osborne, UK

Alexandra C. Pacurariu, The Netherlands

Clive Page, UK

Shanthi Pal, Switzerland

Jason N. Peart, Australia

Alyssa M. Peckham, USA

Elisabetta Poluzzi, Italy

Maria da Conceição Constantino Portela, Portugal

Koen B. Pouwels, The Netherlands

Nicole L. Pratt, Australia

Scott Proestel, USA

Jill Pulley, USA

Gillian Raab, UK

Emanuel Raschi, Italy

Luke V. Rasmussen, USA

Alexandra E. Rätz Bravo, Switzerland

Nigel Rawson, Canada

Arie Regev, USA

Jenna M. Reps, UK

Lidia M. L Rodrigues, Brazil

Leàn Rolfes, The Netherlands

Rachel Rosenstein, USA

Elizabeth Roughead, Australia

Leyla Sahin, USA

Abeed Sarker, USA

Sirarat Sarntivijai, UK

Stephen Schachterle, USA

Sven Schmiedl, Germany

Samuel Searle, Canada

John D. Seeger, USA

Alissa Segal, USA

Jodi Beth, Segal, USA

Helmy Selman, Italy

John R. Senior, USA

Tavpritesh Sethi, India

Eric D. Shah, USA

Sepehr Shakib, Australia

Ken Sharpe, Australia

Ju-Young Shin, Republic of Korea

Susan M. Sinclair, USA

Sonal Singh, USA

Laurianne Sitbon, Australia

Jim Slattery, UK

Karen Smith, USA

Rachel E. Sobel, USA

Rachida Soulaymani-Bencheikh, Morocco

Edoardo Spina, Italy

Julia Spoendlin, USA

Kristina Star, Sweden

Stella Stergiopoulos, USA

Daniel Stow, UK

Jeremy S. Stultz, USA

Leilei Sun, China

Yoshinori Takeuchi, Japan

Suzanne Tamang, USA

Leonardo Tamariz, USA

Carlyn Tan, USA

Huilin Tang, USA

Michael V. Tatley, New Zealand

Anders Ternhag, Sweden

Rolf Teschke, Germany

Helene Theophile, France

Laurie Tomlinson, UK

Jan Van Amsterdam, The Netherlands

A. C. Van Grootheest, The Netherlands

Florence Van Hunsel, The Netherlands

B. Vanhaesebroeck, UK

Mauro Venegoni, Italy

Priya Vijayvargiya, USA

Jiri Vlcek, Czech Republic

Erica Voss, USA

Izyan A. Wahab, Malaysia

Alexander Y. Walley, USA

Shuhang Wang, China

Shirley Wang, USA

Paul B. Watkins, USA

Rachel S. Wightman, USA

Jonathan Williman, New Zealand

Raymond L. Woosley, USA

Cameron Wright, Australia

Lang Wu, USA

Cao Xiao, USA

Kunihiro Yamaoka, Japan

Barbara Yankey, USA

Hong Yu, USA

Siyan Zhan, China

In addition, we would like to thank the members of the journal’s Honorary Editorial Board, who have acted as peer reviewers and authors, and have provided guidance on journal content, policy and processes:

G. Caleb Alexander, USA

Laurent Azoulay, Canada

Bernard Bannwarth, France

Joanne Barnes, New Zealand

David W. Bates, USA

Jean-François Bergmann, France

Frank M. C. Besag, UK

Elliot G. Brown, UK

Nicholas Buckley, Australia

Ric O. Day, Australia

Alexander N. O. Dodoo, Ghana

I. Ralph Edwards, Sweden

Antonie C. G. Egberts, The Netherlands

Stephen J. W. Evans, UK

Adolfo Figueiras, Spain

Joshua Gagne, USA

Stephen A. Goldman, USA

Arnold J. Gordon, USA

Staffan Hägg, Sweden

Kenneth Y. Hartigan-Go, Philippines

Laurence Howes, Australia

David Hunt, UK

Susan Jick, USA

Stephan Krähenbühl, Switzerland

Kiyoshi Kubota, Japan

Joan-Ramon Laporte, Spain

Deborah Layton, UK

Hervé Le Louet, France

James H. Lewis, USA

Marie Lindquist, Sweden

Yoon K. Loke, UK

Christopher R. Meier, Switzerland

Ronald Meijboom, The Netherlands

Peter G. M. Mol, The Netherlands

Jean-Louis Montastruc, France

Nichoals Moore, France

G. Niklas Norén, Sweden

Munir Pirmohamed, UK

Ruth L. Savage, New Zealand

Nigam Shah, USA

Rashmini R. Shah, UK

Saad Shakir, UK

Neil Shear, Canada

Olav Spigset, Norway

Nicholas P. Tatonetti, USA

Gianluca Trifirò, Italy

Marco Tuccori, Italy

Eugene P. van Puijenbroek, The Netherlands

Lynda V. Wilton, UK

Ian C. K. Wong, UK

Li Zhang, China

We do hope that you have found the articles published throughout the year in Drug Safety to be interesting and informative. The editorial schedule for 2019 is well under way, and we are looking forward to bringing you many high-quality and authoritative articles over the coming year.

With best wishes,

Nitin Joshi

Editor-in-Chief, Drug Safety