The COVID‐19 infection can be diagnosed from upper and lower respiratory sources including the oropharynx, nasopharynx, sputum, and bronchial fluid. It appears to be extremely important to properly collect nasopharyngeal swabs reaching the posterior rhinopharyngeal tonsil region. To correctly perform the nasal swab, the patient must be seated with the back of their head against the headrest. The swab is inserted in the nose horizontally, along an imaginary line between the nostril and the ear (tragus). Upon reaching the posterior wall of the nasopharynx, it is not necessary to rotate the swab in place according to a study, before gently removing the swab [1]. The investigator has to be careful not to insert the swab in an upwards direction or limit the sampling to only the anterior portion of the nasal cavity as this would reduce the probability of taking a significant amount of viral RNA (Fig. 1).

Fig. 1
figure 1

The swab should be inserted in the nose horizontally along an imaginary line between the nostril and the ear (tragus). The investigator has to be careful not to insert the swab in an upwards direction or limit the sampling to only the anterior portion of the nasal cavity

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In a study, suboptimal biological sampling resulted in false-negative COVID-19 tests [droplet digital polymerase chain reaction (ddPCR)]. The results showed the importance of proper training and technique in the collection of nasopharyngeal specimens [2]. For this procedure, there still exist different instructions from professional societies and publications [3, 4]. The Centers for Disease Control and Prevention (CDC) recommend tilting patient’s head back in 70° [5]. Such an angle of inclination complicates to perform a correct nasal swab by an uneducated health care worker or a nonprofessional (Fig. 2).

Fig. 2
figure 2

The Centers for Disease Control and Prevention (CDC) recommend tilting patient’s head back in 70°. Such an angle of inclination complicate to perform a correct nasal swab by an uneducated health care worker. If the swab is inserted in the nose, horizontally basal skull perforation and injuries due to an incorrect technique will happen

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As the incidence of new cases of coronavirus disease increased exponentially, the use of viral swabs to collect nasopharyngeal specimens were increasing drastically and therefore healthcare workers military staff and uneducated nonprofessional’s were ordered to make these swabs. Subsequently, case reports reported about basal skull perforation, cerebrospinal fluid fistula and injury due to an incorrect technique [6, 7].

An anatomically accurate three-dimensional (3D) printed model of the nose was used during training sessions for healthcare workers for nasopharyngeal swabs. This enhanced realistic, efficient, and safe nasopharyngeal swab training, and helped to ensure that swab results are as accurate as possible [8]. Implementation of nasal anatomy education and nasopharyngeal swab technique can improve accurate COVID testing [9].

In a study, three blinded rhinologists rated 126 videos (YouTube) for accuracy of swab angle and depth. Only in 44% of the videos nasal swab were correctly performed associated with the swab operator identifying as a medical professional (96%) [10].

Although professional societies started to report about this unacceptable situation, no publication reported about this health endangerment. In this time of overwhelming information and diversity of opinions, it is necessary to report about this in the hope, all media and TV reports will follow this article to show correctly performed nasal swabs to reduce false-negative COVID-19 tests and injury.