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Cross-sectional sero-prevalence study of Peste des Petits Ruminants (PPR) in goats of Syangja and Kaski districts of Nepal

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Abstract

A cross-sectional study was conducted to determine sero-prevalence of Peste des Petits Ruminants (PPR) among goat population of outbreak suspected areas; Kaski and Syangja districts of Nepal. A total of 460 goat serum samples were tested by using c-ELISA for the presence of antibodies against PPR. Out of the 460 samples tested, 380 samples were found positive, giving overall sero-positivity of 82.60%. Significantly higher sero-prevalence was found (*P < 0.05) in females (87.50%) compared to males (70.45%) and crossbreed goats were found highly susceptible than the pure breed goats (*P < 0.05). Likewise, higher sero-prevalence of PPR was observed in adults and cross breed goats compared to their counterparts and significantly higher sero-prevalence was observed in Syangja district compared to Kaski. Thus, adults, females and cross-breeds populations of goats are at higher risk of PPR whereas geographically, goat population of Syangja district were found significantly prone to PPR. Appropriate control measures, such as ring vaccination can be followed to prevent the potential outbreak situation.

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Source: DoAH [17]

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References

  1. Abdalla AS, Majok AA, El Malik KH, Ali AS. Sero-prevalence of peste des petits ruminants virus (PPRV) in small ruminants in Blue Nile, Gadaref and North Kordofan States of Sudan. J Public Heal Epidemiol. 2012;4:59–64.

    Google Scholar 

  2. Abubakar M, Rasool MH, Manzoor S, Saqalein M, Rizwan M, et al. Evaluation of risk factors for peste des petits ruminants virus in sheep and goats at the wildlife-livestock interface in Punjab province, Pakistan. Biomed Res Int. 2016;2016:7826245.

    PubMed  PubMed Central  Google Scholar 

  3. Abubakar M, Zahur AB, Afzal M, Ali Q, Gonzales J. Peste des Petits Ruminants (PPR) in Pakistan: analysis of a national level serological data. Small Rumin Res. 2017;155:57–65.

    Article  Google Scholar 

  4. Abubakar M, Mahapatra M, Muniraju M, Arshed MJ, Khan EH, Banyard AC, et al. Serological detection of antibodies to peste des petits ruminants virus in large ruminants. Transbound Emerg Dis. 2017;64:513–9.

    Article  PubMed  CAS  Google Scholar 

  5. Al-Majali AM, Hussain NO, Amarin NM, Majok AA. Seroprevalence of, and risk factors for, peste des petits ruminants in sheep and goats in Northern Jordan. Prev Vet Med. 2008;85:1–8.

    Article  PubMed  Google Scholar 

  6. Annual Technical Report [Internet]. Tripureshwor, Kathmandu, Central Veterinary Laboratory, Department of Livestock Services, Ministry of Livestock Development, Government of Nepal. 2015. http://www.cvl.gov.np/uploads/files/5324820354.pdf. Accessed 22 Dec 2017.

  7. Baazizi R, Mahapatra M, Clarke BD, Ait-Oudhia K, Khelef D, Parida S. Peste des petits ruminants (PPR): a neglected tropical disease in Maghreb region of North Africa and its threat to Europe. PLoS ONE. 2017;12:e0175461.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  8. Balamurugan V, Saravanan P, Sen A, Rajak KK, Venkatesan G, Krishnamoorthy P, et al. Prevalence of peste des petits ruminants among sheep and goats in India. J Vet Sci. 2012;13:279–85.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Balamurugan V, Krishnamoorthy P, Raju DSN, Rajak KK, Bhanuprakash V, Pandey AB, et al. Prevalence of Peste-des-petits-ruminant virus antibodies in cattle, buffaloes, sheep and goats in India. Virusdisease. 2014;25:85–90.

    Article  PubMed  CAS  Google Scholar 

  10. Balamurugan V, Das S, Raju DSN, Chakravarty I, Nagalingam M, Hemadri D, et al. Prevalence of peste des petits ruminants in goats in North-East India. Virusdisease. 2014;25:488–92.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  11. Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gen Virol. 2010;91:2885–97.

    Article  PubMed  CAS  Google Scholar 

  12. Banyard AC, Wang Z, Parida S. Peste des petits ruminants virus, eastern Asia. Emerg Infect Dis. 2014;20:2176–8.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  13. Bello AM, Lawal JR, Dauda J, Wakil Y, Lekko YM, Mshellia ES, et al. Research for peste des petits ruminants (PPR) virus antibodies in goats, sheep and gazelle from Bauchi and Gombe states, North Eastern Nigeria. Direct Res J Agric Food Sci. 2016;4:193–8.

    Google Scholar 

  14. Bhaskar SR, Deshmukh VV, Chopade NA, Rautmare SS. Seroprevalence of Peste Des Petits Ruminants in Maharashtra. Indian J Anim Res. 2009;43:285–7.

    Google Scholar 

  15. Daniel WW, editor. Biostatistics: a foundation for analysis in the health sciences. 7th ed. New York: Wiley; 1999.

    Google Scholar 

  16. Dhar P, Sreenivasa B, Barrett T, Corteyn M, Singh R, Bandyopadhyay S. Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol. 2002;88:153–9.

    Article  PubMed  Google Scholar 

  17. DoAH. Annual Epidemiological Bulletin. Tripureshwor, Kathmandu: Veterinary Epidemiological Centre, Directorate of Animal Health; 2015.

  18. El-Yuguda AD, Abubakar MB, Nabi AB, Andrew A, Baba SS. Outbreak of peste des petits ruminant in an unvaccinated Sahel goat farm in Maiduguri, Nigeria. Afr J Biomed Res. 2008;12:83–7.

    Google Scholar 

  19. Islam M, Hasan A, Yousuf A, Islam UK, Mahfuz M, Khan A. Seroprevalence of Peste des Petits Ruminant Virus specific antibody in goats in different regions of Bangladesh. J Adv Vet Anim Res. 2016;7710:127–33.

    Article  Google Scholar 

  20. Janus A, Tresamol PV, Saseendranath MR, Vijayakumar K, Pillai UN. Seroprevalence of PPR in goats in Kerala by cELISA. J Vet Anim Sci. 2009;40:15–6.

    Google Scholar 

  21. Jha VK, Singh DB, Thakuri KC, Gautam SP. National workshop. In: Gurung TB, Joshi BR, Singh UM, Paudel KP, Shrestha BS, Rijal KP et al (eds) Research & development strategies for goat enterprises in Nepal. 2013. https://www.researchgate.net/profile/Tek_Gurung/publication/257143203_Proceedings_of_the_National_Workshop_on_Research_and_Development_Strategies_for_Goat_Enterprises_in_Nepal/links/0deec524bc1267ea34000000/Proceedings-of-the-National-Workshop-on-Research. Accessed 9 Nov 2017

  22. Khakural GP. Surveillance of goat diseases in the Western Hills of Nepal. Nepal J Sci Technol. 2003;5:37–40.

    Google Scholar 

  23. Khakural GP, Upreti CR. Proceedings of the 3rd national workshop on livestock and fisheries research in Nepal. 1999. p. 148–52. http://coin.fao.org/coin-static/cms/media/22/14376249192440/a_compendium_of_livestock_and_fisheries_research_highlights_in_nepal.pdf. Accessed 9 Nov 2017.

  24. Khan HA, Siddique M, Sajjad-Ur-Rahman, Abubakar M, Ashraf M. The detection of antibody against peste des petits ruminants virus in Sheep, Goats, Cattle and Buffaloes. Trop Anim Health Prod. 2008;40:521–7.

    Article  PubMed  Google Scholar 

  25. Kihu SM, Gachohi JM, Ndungu EK, Gitao GC, Bebora LC, John NM, et al. Sero-epidemiology of Peste des petits ruminants virus infection in Turkana County, Kenya. BMC Vet Res. 2015;11:87.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Mahajan S, Agrawal R, Kumar M, Mohan A, Pande N. Risk of seroconversion to peste des petits ruminants (PPR) and its association with species, sex, age and migration. Small Rumin Res. 2012;104:195–200.

    Article  Google Scholar 

  27. Mariner JC, Jones BA, Rich KM, Thevasagayam S, Anderson J, Jeggo M, et al. The opportunity to eradicate peste des petits ruminants. J Immunol. 2016;196:3499–506.

    Article  PubMed  CAS  Google Scholar 

  28. Mehmood A, Ali Q, Gadahi JA, Malik SA, Shah SI. Detection of peste des petits ruminants (PPR) virus antibodies in sheep and goat populations of the north west frontier province (NWFP) of Pakistan by competitive elisa (cELISA). Vet World. 2009;2:333–6.

    Google Scholar 

  29. Naing L, Winn T, Rusli BN. Practical issues in calculating the sample size for prevalence studies. Arch Orofac Sci. 2006;1:9–14.

    Google Scholar 

  30. Nizamani AR, Nizamani ZA, Umrani AP, Dewani P, Vandiar MA, Gandahi JA, et al. Prevalence of peste des petits ruminants virus antibodies in small Ruminantsin Sindh, Pakistan. J Anim Plant Sci. 2015;25:1515–9.

    Google Scholar 

  31. Ozkul A, Akca Y, Alkan F, Barrett T, Karaoglu T, Dagalp SB, et al. Prevalence, distribution, and host range of Peste des petits ruminants virus, Turkey. Emerg Infect Dis. 2002;8:708–12.

    Article  PubMed  Google Scholar 

  32. Parida S, Muniraju M, Mahapatra M, Muthuchelvan D, Buczkowski H, Banyard AC. Peste des petits ruminants. Vet Microbiol. 2015;181:90–106.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  33. Salih H, Elfadil A, Saeed I, Ali Y. Seroprevalence and risk factors of Peste des Petits Ruminants in sheep and goats in Sudan. J Adv Vet Anim Res. 2014;1:42–9.

    Article  Google Scholar 

  34. Sarker S, Islam H. Prevalence and risk factor assessment of peste des petits ruminants in goats in Rajshahi, Bangladesh. Vet World. 2011;4:546–9.

    Article  Google Scholar 

  35. Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, et al. Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis. 2009;15:299–301.

    Article  PubMed  PubMed Central  Google Scholar 

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Acharya, N., Poudel, S.P. & Acharya, K.P. Cross-sectional sero-prevalence study of Peste des Petits Ruminants (PPR) in goats of Syangja and Kaski districts of Nepal. VirusDis. 29, 173–179 (2018). https://doi.org/10.1007/s13337-018-0449-1

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