Skip to main content
SpringerLink
Log in

Making good use of the byproducts of cultivation: green synthesis and antibacterial effects of silver nanoparticles using the leaf extract of blueberry

  • Original Article
  • Published:
Journal of Food Science and Technology Aims and scope Submit manuscript

Abstract

In this study, we made an effort to use blueberry leaves extract as a reducing and a capping agent to biosynthesize silver nanoparticles (AgNPs). The successful formation of AgNPs was confirmed with UV–visible spectroscopy, transmission electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. Furthermore, their antimicrobial activities against four kinds of multi drug resistant clinical pathogens and aquatic pathogens were investigated. The results showed that as-prepared AgNPs exhibited broad-spectrum antibacterial activities. The antibacterial effects of the AgNPs based on the structural damage and DNA degradation of the tested bacteria were also studied. The green synthesis of AgNPs using blueberry leaf extract, which provided a new idea on the use of the byproducts of blueberry harvesting.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  • Abbai R, Mathiyalagan R, Markus J, Kim YJ, Wang C, Singh P, Ahn S, Farh MA, Yang DC (2016) Green synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng. Int J Nanomed 11:3131–3143

    Article  CAS  Google Scholar 

  • Deng Y, Yang G, Yue J, Qian B, Liu Z, Wang D, Zhong Y, Zhao Y (2014) Influences of ripening stages and extracting solvents on the polyphenolic compounds, antimicrobial and antioxidant activities of blueberry leaf extracts. Food Control 38:184–191

    Article  CAS  Google Scholar 

  • Dubey SP, Lahtinen M, Sillanpää M (2010) Tansy fruit mediated greener synthesis of silver and gold nanoparticles. Process Biochem 45:1065–1071

    Article  CAS  Google Scholar 

  • Ferlemi AV, Lamari FN (2016) Berry Leaves: an alternative source of bioactive natural products of nutritional and medicinal value. Antioxidants 5:17–26

    Article  Google Scholar 

  • Harris CS, Burt AJ, Saleem A, Le PM, Martineau LC, Haddad PS, Bennett SA, Arnason JT (2007) A single HPLC-PAD-APCI/MS method for the quantitative comparison of phenolic compounds found in leaf, stem, root and fruit extracts of Vaccinium angustifolium. Phytochem Anal 18:161–169

    Article  CAS  Google Scholar 

  • Huang J, Li Q, Sun D, Lu Y, Su Y, Yang X, Wang H, Wang Y, Shao W, He N, Hong J, Chen C (2007) Biosynthesis of silver and gold nanoparticles by novel sundried Cinnamomum camphora leaf. Nanotechnol 18:105104–105114

    Article  Google Scholar 

  • Kaviya S, Santhanalakshmi J, Viswanathan B (2011) Green synthesis of silver nanoparticles using Polyalthia longifolia leaf extract along with D-sorbitol: study of antibacterial activity. J Nanotechnol 2011:1687–9503

    Article  Google Scholar 

  • Liu FH, Wang L, Gu L, Zhao W, Su HY, Cheng XH (2015) Higher transcription levels in ascorbic acid biosynthetic and recycling genes were associated with higher ascorbic acid accumulation in blueberry. Food Chem 188:399–405

    Article  CAS  Google Scholar 

  • Malhotra A, Dolma K, Kaur N, Rathore YS, Ashish Mayilraj S, Choudhury AR (2013) Biosynthesis of gold and silver nanoparticles using a novel marine strain of Stenotrophomonas. Bioresour Technol 142:727–731

    Article  CAS  Google Scholar 

  • Miri A, Sarani M, Bazaz MR, Darroudi M (2015) Plant-mediated biosynthesis of silver nanoparticles using Prosopis farcta extract and its antibacterial properties. Spectrochim Acta A 141:287–291

    Article  CAS  Google Scholar 

  • Noginov MA, Zhu G, Bahoura M, Adegoke J, Small C, Ritzo BA, Drachev VP, Shalaev VM (2006) The effect of gain and absorption on surface plasmon in metal nanoparticles. Appl Phys B 86:455–460

    Article  Google Scholar 

  • Patil RS, Kokate MR, Kolekar SS (2012) Bioinspired synthesis of highly stabilized silver nanoparticles using Ocimum tenuiflorum leaf extract and their antibacterial activity. Spectrochim Acta A 91:234–238

    Article  CAS  Google Scholar 

  • Pervin M, Hasnat MA, Lim BO (2013) Antibacterial and antioxidant activities of Vaccinium corymbosum L. leaf extract. Asian Pac J Trop Dis 3:444–453

    Article  Google Scholar 

  • Prashanth S, Menaka I, Muthezhilan R, Navin Kumar S (2001) Synthesis of plant-mediated silver nano particles using medicinal plant extract and evaluation of its anti microbial activities. Int J Eng Sci Technol 3:6235–6250

    Google Scholar 

  • Priya RS, Geetha D, Ramesh PS (2016) Antioxidant activity of chemically synthesized AgNPs and biosynthesized Pongamia pinnata leaf extract mediated AgNPs—a comparative study. Ecotoxicol Environ Saf 134(Pt 2):308–318

    Article  CAS  Google Scholar 

  • Ramamurthy CH, Padma M, Samadanam ID, Mareeswaran R, Suyavaran A, Kumar MS, Premkumar K, Thirunavukkarasu C (2013) The extra cellular synthesis of gold and silver nanoparticles and their free radical scavenging and antibacterial properties. Colloid Surf B 102:808–815

    Article  CAS  Google Scholar 

  • Rao YS, Kotakadi VS, Prasad TN, Reddy AV, Sai Gopal DV (2013) Green synthesis and spectral characterization of silver nanoparticles from Lakshmi tulasi (Ocimum sanctum) leaf extract. Spectrochim Acta A 103:156–159

    Article  Google Scholar 

  • Sahu N, Soni D, Chandrashekhar B, Sarangi BK, Satpute D, Pandey AR (2013) Synthesis and characterization of silver nanoparticles using Cynodon dactylon leaves and assessment of their antibacterial activity. Bioprocess Biosyst Eng 36:999–1004

    Article  CAS  Google Scholar 

  • Singh S, Saikia JP, Buragohain AK (2013) A novel ‘green’ synthesis of colloidal silver nanoparticles (SNP) using Dillenia indica fruit extract. Colloid Surf B 102:83–85

    Article  CAS  Google Scholar 

  • Soman S, Ray JG (2016) Silver nanoparticles synthesized using aqueous leaf extract of Ziziphus oenoplia (L.) Mill: characterization and assessment of antibacterial activity. J Photochem Photobiol B 163:391–402

    Article  CAS  Google Scholar 

  • Song FY, Su HY, Yang N, Zhu LY, Cheng JS, Wang L, Cheng XH (2016) Myo-inositol content determined by myo-inositol biosynthesis and oxidation in blueberry fruit. Food Chem 210:381–387

    Article  CAS  Google Scholar 

  • Velmurugan P, Anbalagan K, Manosathyadevan M, Lee KJ, Cho M, Lee SM, Park JH, Oh SG, Bang KS, Oh BT (2014) Green synthesis of silver and gold nanoparticles using Zingiber officinale root extract and antibacterial activity of silver nanoparticles against food pathogens. Bioprocess Biosyst Eng 37:1935–1943

    Article  CAS  Google Scholar 

  • Velusamy P, Das J, Pachaiappan R, Vaseeharan B, Pandian K (2015) Greener approach for synthesis of antibacterial silver nanoparticles using aqueous solution of neem gum (Azadirachta indica L.). Ind Crops Prod 66:103–109

    Article  CAS  Google Scholar 

  • Wang L, Liu CC, Wang YY, Xu H, Su HS, Cheng XH (2016a) Antibacterial activities of the novel silver nanoparticles biosynthesized using Cordyceps militaris extract. Curr Appl Phys 16:969–973

    Article  Google Scholar 

  • Wang L, Xu H, Gu L, Han TT, Wang S, Meng FB (2016b) Bioinspired synthesis, characterization and antibacterial activity of plant-mediated silver nanoparticles using purple sweet potato (Ipomoea batatas L.) root extract. Mater Technol 31:437–442

    Article  CAS  Google Scholar 

  • Yilmaz M, Turkdemir H, Kilic MA, Bayram E, Cicek A, Mete A, Ulug B (2011) Biosynthesis of silver nanoparticles using leaves of Stevia rebaudiana. Mater Chem Phys 130:1195–1202

    Article  CAS  Google Scholar 

  • Zayed MF, Eisa WH, Shabaka AA (2012) Malva parviflora extract assisted green synthesis of silver nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc 98:423–438

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Natural Science Foundation of China (Nos. 31570649; 31470661; 31400447), Key Research and Development Program of Shandong Province (No. 2016GNC111016), the Project of Shandong Province Higher Educational Science and Technology Program (No. J15LE03) and the Key Research and Development Program of Yantai (No. 2016ZH059).

Author information

Author notes

  1. Kun Li, Chenyu Ma and Tiancai Jian have contributed equally to this article.

Authors and Affiliations

  1. School of Life Sciences, Ludong University, Yantai, China

    Kun Li, Chenyu Ma, Tiancai Jian, Hushan Sun & Lei Wang

  2. School of Chemistry and Materials Sciences, Ludong University, Yantai, China

    Hui Xu

  3. School of Agriculture, Ludong University, Yantai, China

    Weihuan Li, Hongyan Su & Xianhao Cheng

Authors
  1. Kun Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chenyu Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tiancai Jian
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hushan Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Lei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hui Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Weihuan Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hongyan Su
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Xianhao Cheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Lei Wang or Hui Xu.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 152 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, K., Ma, C., Jian, T. et al. Making good use of the byproducts of cultivation: green synthesis and antibacterial effects of silver nanoparticles using the leaf extract of blueberry. J Food Sci Technol 54, 3569–3576 (2017). https://doi.org/10.1007/s13197-017-2815-1

Download citation

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13197-017-2815-1

Keywords

Search

Navigation