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Non-carcinogenic Health Risk Assessment of Aluminium Ingestion Via Drinking Water in Malaysia

  • S.I. : Drinking Water Quality and Public Health
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Abstract

Exposure to aluminium (Al) is inevitable in the daily life because of its abundance in the environmental media through natural processes. Meanwhile, several studies have reported a positive association between Alzheimer’s disease and a higher level of Al ingestion through drinking water. The present study is the first of its kind in Malaysia which predicts the human health risk of Al ingestion via drinking water at the Langat River Basin, Malaysia. Water samples were collected during 2015–2016 from the four stages of drinking water supply chain at the basin to determine the concentrations of Al by the Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The determined mean concentration of Al in river 2.50E−01 ± 1.89E−01 mg/L crossed the Malaysian drinking water quality standard of 0.2 mg/L. The higher concentration of Al in the Langat River might be due to natural weathering of Al-bearing minerals. The mean Al concentrations in the treated water by the treatment plants, household’s tap and after filtration water, respectively, were found to be within the Malaysian drinking water quality standard. This study suggests that there is no potential human health risk of Al ingestion through drinking water (HQ = 3.81E−03 ± 1.82E−03) at 95% confidence level in the basin because the hazard quotient (HQ) value is less than 1. However, the authorities need to be careful of excessive ingestion of Al via drinking water because the water treatment plants in the basin follow the conventional method to treat raw water. The turbidity in the tropical Langat River changes very frequently; thus, the doses of Al2(SO4)3 for water disinfection are very crucial. Therefore, reverse osmosis technology can be introduced in the treatment plants because the United States Environmental Protection Agency has recommended that it can remove all types of metal > 90% from treated water.

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Fig. 1

Modified from LUAS (2013)

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References

  • Ab Razak NH, Praveena SM, Aris AZ, Hashim Z (2016) Quality of Kelantan drinking water and knowledge, attitude and practice among the population of Pasir Mas, Malaysia. Public Health. https://doi.org/10.1016/j.puhe.2015.11.006

    Article  Google Scholar 

  • ADFM (2017) About Alzheimer’s. Alzheimer’s Disease Foundation Malaysia. http://www.adfm.org.my/Home/about-alzheimer-s/stages. Accessed 10 Dec 2017

  • Adimalla N, Li P (2018) Occurrence, health risks and geochemical mechanisms of fluoride and nitrate in groundwater of the rock-dominant semi-arid region, Telangana State, India. Hum Ecol Risk Assess. https://doi.org/10.1080/10807039.2018.1480353

    Article  Google Scholar 

  • Ahmed MF, Lubna A, Choo TG, Rahim MC, Mazlin M (2016a) A review on the chemical pollution of Langat River, Malaysia. Asian J Water Environ Pollut 13(1):9–15

    Article  CAS  Google Scholar 

  • Ahmed MF, Alam L, Ta GC, Mohamed CAR, Mokhtar M (2016b) A review on the environmental pollution of Langat River, Malaysia. Asian J Water Environ Pollut 13(4):25–31

    Article  CAS  Google Scholar 

  • Alam MM (2014) Linkages between climatic changes and food security among the poor and low-income households in the East Coast Economic Region (ECER), Malaysia. Doctor of Philosophy, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia

  • Al-Badaii F, Shuhaimi-Othman M, Gasim MB (2013) Water quality assessment of the Semenyih river, Selangor, Malaysia. J Chem 15:17–18. https://doi.org/10.1155/2013/871056

    Article  CAS  Google Scholar 

  • Aquathin (2017) Particle size removal: range by filtration & reverse osmosis. http://www.aquathin.com/sites/default/files/particle%20size.pdf. Accessed 22 May 2017

  • Aris AZ, Puad NHA, Shafie NA, Juen LL, Mangala S (2014) The chemometric approach as a useful tool in the identification of metal pollution sources of Riverine-Mangrove Sediment of Kota Marudu, Sabah, Malaysia. J Environ 7(2):70–78. https://doi.org/10.14456/ea.2014.26

    Article  Google Scholar 

  • ATSDR (2008) Toxicological Profile For Aluminum. Atlanta, Georgia: Agency for Toxic Substances and Disease Registry. U.S. Department of Health and Human Services. https://www.atsdr.cdc.gov/toxprofiles/tp22.pdf. Accessed 11 Dec 2017

  • ATSDR (2017) Background and Environmental Exposures to Aluminium in the United States. Agency for Toxic Substances and Disease Registry. https://www.atsdr.cdc.gov/toxprofiles/tp22-c2.pdf. Accessed 9 Dec 2017

  • Daud Z, Mohamed CAR (2013) Preliminary Studies on Distribution and Behavior of Rare Earth Elements in the Sungai Balok, Kuantan. Paper presented at the Advancements in Marine and freshwater Sciences International Symposium

  • DOE (2003) Study approach and methodology. In: Shaaban MG, Alwan HK, Jaafar MN, Abdullah AR, Ismail MZ, Idris A, Hamidon AB, Sharom A, Zakri IM, Othman PF, Hussin WSW (eds) Study on pollution prevention and water quality improvement program of Sungai Langat. Department of Environment, Kuala Lumpur

    Google Scholar 

  • DOS (2013) Population Distribution by Local Authority Areas and Mukims 2010. Putrajaya: Department of Statistics, Malaysia. http://newss.statistics.gov.my/newss-portalx/ep/epProductFreeDownloadSearch.seam. Accessed 23 June 2016

  • Dzulfakar MA, Shaharuddin MS, Muhaimin AA, Syazwan AI (2011) Risk assessment of aluminum in drinking water between two residential areas. Water 3(3):882–893

    Article  CAS  Google Scholar 

  • Elfithri R (2016a) Establishment of Sustainability Science Demonstration Pilot Project on Restoring and Managing Langat River, Malaysia for Future. Bangi: Institute for Environment and Development. http://jfit-for-science.asia/wp-content/uploads/502_Sustainability-Science-Pilot-Project-Langat-River-Malaysia.pdf. Accessed 24 Sept 2017

  • Elfithri R (2016b) Establishment of sustainability science demonstration pilot project on restoring and managing Langat River, Malaysia for future. Institute for Environment and Development, Bangi. http://mucp-mfit.org/wp-content/uploads/1a-Langat-ELFITHRI-LESTARI.pdf. Accessed 24 Sept 2017

  • Farizwana SMR, Mazrura S, Zurahanim FA, Ahmad RG (2010) Determination of aluminium and physicochemical parameters in the palm oil estates water supply at Johor, Malaysia. J Environ Public Health 2010:1–7

    Article  CAS  Google Scholar 

  • Fasihnikoutalab MH, Asadi A, Huat BK, Ball RJ, Pourakbar S, Singh P (2016) Utilisation of carbonating olivine for sustainable soil stabilisation. Environ Geotech 17:17–18. https://doi.org/10.1680/jenge.15.00018

    Article  Google Scholar 

  • Flaten TP (1990) Geographical associations between aluminium in drinking water and death rates with dementia (including Alzheimer’s disease), Parkinson’s disease and amyotrophic lateral sclerosis in Norway. Environ Geochem Health 12(1–2):152–167

    Article  CAS  Google Scholar 

  • Flaten TP (2001) Aluminium as a risk factor in Alzheimer’s disease, with emphasis on drinking water. Brain Res Bull 55(2):187–196

    Article  CAS  Google Scholar 

  • GRAPHIQ (2017) Alzheimer’s and Other Dementias in Malaysia, Statistics on Overall Impact and Specific Effect on Demographic Groups. Graphiq LLC. http://global-disease-burden.healthgrove.com/l/55069/Alzheimer-s-and-Other-Dementias-in-Malaysia. Accessed 10 Dec 2017

  • Hajira S, Shaharuddin MS (2015) Risk assessment of aluminum residue in drinking water of residents in Sandakan, Sabah. Asia Pacif Environ Occup Health J 1(1):29–35

    Google Scholar 

  • Ibrahim N, Abdul AH, Yusoff MS (2015) River bank filtration: study of Langat River water and borehole water quality. Appl Mech Mater 773:1194–1198

    Article  Google Scholar 

  • Juahir HH (2009) Water quality data analysis and modeling of the Langat river basin. Doctor of Philosophy, University of Malaya, Kuala Lumpur, Malaysia. http://repository.um.edu.my/1223/5/Chapter%203%20Revised.pdf. Accessed 7 Feb 2016

  • Juahir H, Zain SM, Yusoff MK, Hanidza TT, Armi AM, Toriman ME, Mokhtar M (2011) Spatial water quality assessment of Langat River Basin (Malaysia) using environmetric techniques. Environ Monit Assess 173(1–4):625–641

    Article  Google Scholar 

  • Kawahara M, Kato-Negishi M (2011) Link between aluminum and the pathogenesis of Alzheimer’s disease: the integration of the aluminum and amyloid cascade hypotheses. Int J Alzheimer’s Dis. https://doi.org/10.4061/2011/276393

    Article  Google Scholar 

  • Kim CT (2012) Malaysian water sector reform—policy and performance. PhD thesis, Wageningen University, Wageningen, The Netherlands. http://edepot.wur.nl/240502. Accessed 10 Jan 2017

  • Leong KH, Tan LB, Mustafa AM (2007) Contamination levels of selected organochlorine and organophosphate pesticides in the Selangor River, Malaysia between 2002 and 2003. Chemosphere 66(6):1153–1159

    Article  CAS  Google Scholar 

  • Li P, Li X, Meng X, Li M, Zhang Y (2016) Appraising groundwater quality and health risks from contamination in a semiarid region of northwest China. Expo Health 8(3):361–379. https://doi.org/10.1007/s12403-016-0205-y

    Article  CAS  Google Scholar 

  • Li P, Feng W, Xue C, Tian R, Wang S (2017) Spatiotemporal variability of contaminants in lake water and their risks to human health: a case study of the Shahu Lake tourist area, northwest China. Expo Health 9(3):213–225. https://doi.org/10.1007/s12403-016-0237-3

    Article  CAS  Google Scholar 

  • Li P, He X, Li Y, Xiang G (2018) Occurrence and health implication of fluoride in groundwater of loess aquifer in the Chinese Loess Plateau: a case study of Tongchuan. Expo Health, Northwest China. https://doi.org/10.1007/s12403-018-0278-x

    Book  Google Scholar 

  • Lim WY, Aris AZ, Zakaria MP (2012) Spatial variability of metals in surface water and sediment in the Langat river and geochemical factors that influence their water–sediment interactions. Sci World J. https://doi.org/10.1100/2012/652150

    Article  Google Scholar 

  • Lim WY, Aris AZ, Praveena SM (2013a) Application of the chemometric approach to evaluate the spatial variation of water chemistry and the identification of the sources of pollution in Langat River, Malaysia. Arab J Geosci 6(12):4891–4901. https://doi.org/10.1007/s12517-012-0756-6

    Article  CAS  Google Scholar 

  • Lim WY, Aris AZ, Ismail THT, Zakaria MP (2013b) Elemental hydrochemistry assessment on its variation and quality status in Langat River, Western Peninsular Malaysia. Environ Earth Sci 70(3):993–1004. https://doi.org/10.1007/s12665-012-2189-7

    Article  CAS  Google Scholar 

  • Lina A, Shaharuddin M (2017) Health risk associated with aluminium exposure in groundwater: a cross-sectional study in an Orang Asli Village in Jenderam Hilir, Selangor, Malaysia. Malays J Public Health Med 1:58–62

    Google Scholar 

  • LUAS (2013) Sungai Langat, State of the River Report 2011. Shah Alam: Lembaga Urus Air Selangor (LUAS). ISBN 2180-2793

  • LUAS (2017) IRBM Section. Shah Alam: Lambaga Air Urus Sekangor. https://www.luas.gov.my/index.php?option=com_content&view=article&id=120&Itemid=109&lang=en. Accessed 25 Dec 2018

  • Mackin JE, Aller RC (1984) Diagenesis of dissolved aluminum in organic-rich estuarine sediments. Geochim Cosmochim Acta 48(2):299–313

    Article  CAS  Google Scholar 

  • Martyn CN, Coggon DN, Inskip H, Lacey RF, Young WF (1997) Aluminum concentrations in drinking water and risk of Alzheimer’s disease. Epidemiology 8(3):281–286

    Article  CAS  Google Scholar 

  • Meshitsuka S, Aremu DA, Nose T (2002) A risk of Alzheimer’s disease and aluminum in drinking water. Psychogeriatrics 2(4):263–268

    Article  Google Scholar 

  • MOH (2010) Drinking Water Quality Standard. Putrajaya, Malaysia: Engineering Services Division, Ministry of Health, Malaysia. http://kmam.moh.gov.my/public-user/drinking-water-quality-standard.html. Accessed 10 Mar 2015

  • Mora A, Mac-Quhae C, Calzadilla M, Sánchez L (2009) Survey of trace metals in drinking water supplied to rural populations in the eastern Llanos of Venezuela. J Environ Manag 90(2):752–759

    Article  CAS  Google Scholar 

  • Paulson AJ, Curl HC, Feely RA, Krogslund KA, Hanson S (1991) Trace metal and ancillary data in Puget Sound: August 1986: data report (No. PB-91-201590/XAB). Pacific Marine Environmental Lab, Seattle, WA, United States

  • PASSB. Performance Report for 2015 (Air Selangor) 2015. Kuala Lumpur: Pengurusan Air Selangor Sdn Bhd. Malaysia. https://www.syabas.com.my/uploads/FINAL%20REPORT%20new.pdf. Accessed 10 Oct 2018

  • Qaiyum M, Shaharudin M, Syazwan A, Muhaimin A (2011) Health risk assessment after exposure to aluminium in drinking water between two different villages. J Water Resour Protect 3(04):268

    Article  CAS  Google Scholar 

  • Rondeau V, Commenges D, Jacqmin-Gadda H, Dartigues JF (2000) Relation between aluminum concentrations in drinking water and Alzheimer’s disease: an 8-year follow-up study. Am J Epidemiol 152(1):59–66

    Article  CAS  Google Scholar 

  • Santhi V, Sakai N, Ahmad E, Mustafa A (2012) Occurrence of bisphenol A in surface water, drinking water and plasma from Malaysia with exposure assessment from consumption of drinking water. Sci Tot Environ 427:332–338

    Article  CAS  Google Scholar 

  • UNESCO (2010) HELP—hydrology for environment, life and policy. United Nations Educational, Scientific and Cultural Organization, Paris Cedex

    Google Scholar 

  • USEPA (1989) Risk assessment guidance for superfund. Volume I: Human health evaluation manual (part A). EPA/540/1-89/002

  • USEPA (1991) Guidance for data useability in risk assessment (Part A). United States Environmental Protection Agency. https://rais.ornl.gov/documents/USERISKA.pdf. Accessed 7 Dec 2017

  • USEPA (1999) Screening level ecological risk assessment protocol for hazardous waste combustion facilities, toxicity reference values (Appendix E), EPA530-D-99-001C (Vol. 3). United States Environmental Protection Agency, USA

  • USEPA (2005) A regulators’ guide to the management of radioactive residuals from drinking water treatment technologies. United States Environmental Protection Agency. https://www.epa.gov/sites/production/files/2015-05/documents/816-r-05-004.pdf. Accessed 30 May 2017

  • USEPA (2017) Secondary Drinking Water Standards: Guidance for Nuisance Chemicals. United States Environmental Protection Agency. https://www.epa.gov/dwstandardsregulations/secondary-drinking-water-standards-guidance-nuisance-chemicals. Accessed 26 Dec 2018

  • Wang ZW, Ren JL, Zhang GL, Liu SM, Zhang XZ, Liu Z, Zhang J (2015) Behavior of dissolved aluminum in the Huanghe (Yellow River) and its estuary: impact of human activities and sorption processes. Estuar Coast Shelf Sci 153:86–95

    Article  CAS  Google Scholar 

  • WHO (1997) Aluminium. International Programme on Chemical Safety. Environmental Health Criteria 194. World Health Organization, Geneva. http://www.inchem.org/documents/ehc/ehc/ehc194.htm. Accessed 11 Dec 2017

  • WHO (2017) Guidelines for drinking-water quality: fourth edition incorporating the first addendum from World Health Organization. http://apps.who.int/iris/bitstream/10665/254637/1/9789241549950-eng.pdf?ua=1. Accessed 27 Dec 2017

  • Wu J, Sun Z (2016) Evaluation of shallow groundwater contamination and associated human health risk in an alluvial plain impacted by agricultural and industrial activities, mid-west China. Expo Health 8(3):311–329. https://doi.org/10.1007/s12403-015-0170-x

    Article  CAS  Google Scholar 

  • Wu J, Xue C, Tian R, Wang S (2017) Lake water quality assessment: a case study of Shahu Lake in the semi-arid loess area of northwest China. Environ Earth Sci 76:232. https://doi.org/10.1007/s12665-017-6516-x

    Article  CAS  Google Scholar 

  • Yamane T (1967) Statistics: an introductory analysis, 2nd edn. Harper and Row, New York

    Google Scholar 

  • Yap CK (2013) Variations of electrical conductivity between upstream and downstream of Langat River, Malaysia: its significance as a single indicator of water quality deterioration. Pertan J Trop Agric Sci 36(4):299–310

    Google Scholar 

  • Yusuf MA (2001) River water quality and ecosystem health in Langat River Basin, Selangor, Malaysia. PhD thesis, Institute for Environment and Development, Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia

  • Zhang Y, Wu J, Xu B (2018) Human health risk assessment of groundwater nitrogen pollution in Jinghui canal irrigation area of the loess region, northwest China. Environ Earth Sci 77(7):273. https://doi.org/10.1007/s12665-018-7456-9

    Article  CAS  Google Scholar 

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Acknowledgements

The study is supported by the Grants: KRA-2017-022; TRGS/1/2015/UKM/02/5/2 and GUP-2015-029 of the Universiti Kebangsaan Malaysia. The authors are also grateful to the Laboratory of Chemical Oceanography, Faculty of Science & Technology, Universiti Kebangsaan Malaysia as well as to the water treatment plant authorities i.e. Puncak Niaga (M) Sdn. Bhd. and Konsortium Air Selangor Sdn. Bhd. to allow to collect water samples from the outlets of their plants. The authors are also thankful to the Institute of Climate Change, UKM to prepare the study area map.

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  1. Institute for Environment and Development (LESTARI), Universiti Kebangsaan Malaysia (UKM), 43600, Bangi, Selangor Darul Ehsan, Malaysia

    Minhaz Farid Ahmed, Mazlin Bin Mokhtar, Lubna Alam & Goh Choo Ta

  2. School of Environmental and Natural Resource Sciences, Universiti Kebangsaan Malaysia (UKM), 43600, Bangi, Selangor Darul Ehsan, Malaysia

    Che Abd Rahim Mohamed

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  1. Minhaz Farid Ahmed
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Table 8 Household questionnaire for demographic information
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Ahmed, M.F., Mokhtar, M.B., Alam, L. et al. Non-carcinogenic Health Risk Assessment of Aluminium Ingestion Via Drinking Water in Malaysia. Expo Health 11, 167–180 (2019). https://doi.org/10.1007/s12403-019-00297-w

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