Development of a French version of the Endometriosis Health Profile 5 (EHP-5): cross-cultural adaptation and psychometric evaluation
The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version.
A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach’s alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis.
For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach’s alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11–0.85) for superficial endometriosis to 2.56 (95 % CI 2.18–2.93) for deeply infiltrating endometriosis.
The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.
KeywordsEndometriosis Pelvic pain Quality of life questionnaire Psychometric validation
This study was partly funded by the French public funding agency Délégation à la Recherche Clinique et à l’Innovation (DRCI), Versailles, France.
Conflict of interest
All Authors declare that they no conflict of interest.
Compliance with ethical standards
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The 11th ethics research committee of Ile-de-France considered that our study involved no intervention and was thus exempt from the French statute on biomedical research (modified version of Law 2004-806, dated August 9, 2004). We complied with all French statutes concerning patient data, confidentiality, and restrictions.
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