Abstract
Background In the last 30 years, activities of hospital pharmacists have gone through significant changes. Pharmacists are increasingly involved in patient care. Objectives To explore drug-related and logistic problems, interventions, and their outcomes during routine everyday work of hospital pharmacists. Setting Institute for physical medicine and rehabilitation, Banja Luka, Bosnia and Herzegovina. Methods In the period of January 2013–October 2015 a prospective observational study was performed. Medical doctors, nurses, therapists, and patients addressed pharmacists, face-to-face or by telephone, with drug-related problems (DRPs) and/or logistic issues. Main outcome measure Type of DRP or logistic issue, intervention, outcome, initiator and time spent for solving the problem were documented for each consultation. Results Out of 1515 interventions, 48.8% were aimed at solving DRPs. The most common DRPs were the recommendation of a drug or dose and need for additional information about drugs. Drug price and supply were the most prevalent logistic issues. DRPs were more frequently initiated by medical doctors and required more time to solve the problem compared to logistic issues (Mann–Whitney U test, p ≤ 0.001, respectively). The acceptance rate of interventions to solve DRPs (83.7%) was lower compared to logistic issues (95.2%; p ≤ 0.001). Conclusions Hospital pharmacists were faced with an approximately equal number of DRPs and logistic issues during their routine everyday work. The overall acceptance rate of pharmacists’ interventions was high, and the results of our study indicate that there is a need for more involvement of hospital pharmacists in Bosnia and Herzegovina in clinical activities. Impact on practice.
Similar content being viewed by others
References
Viktil KK, Blix HS. The impact of clinical pharmacists on drug-related problems and clinical outcomes. Basic Clin Pharmacol Toxicol. 2008;102:275–80.
Altowaijri A, Phillips CJ, Fitzsimmons D. A systematic review of the clinical and economic effectiveness of clinical pharmacist intervention in secondary prevention of cardiovascular disease. J Manag Care Pharm. 2013;19:408–16.
Schumock GT, Butler MG, Meek PD, Vermeulen LC, Arondekar BV, Bauman JL. Task force on economic evaluation of clinical pharmacy services of the american college of clinical p. evidence of the economic benefit of clinical pharmacy services: 1996–2000. Pharmacotherapy. 2003;23:113–32.
Frontini R, Miharija-Gala T, Sykora J. EAHP, survey 2010 on hospital pharmacy in Europe: part 1. General frame and staffing. Eur J Hosp Pharm. 2012;19:385–7.
Langebrake C, Hilgarth H. Clinical pharmacists’ interventions in a German university hospital. Pharm World Sci. 2010;32:194–9.
Brazinha I, Fernandez-Llimos F. Barriers to the implementation of advanced clinical pharmacy services at Portuguese hospitals. Int J Clin Pharm. 2014;36:1031–8.
Acheampong F, Anto BP. Perceived barriers to pharmacist engagement in adverse drug event prevention activities in Ghana using semi-structured interview. BMC Health Serv Res. 2015;15:361.
Bedouch P, Sylvoz N, Charpiat B, Juste M, Roubille R, Rose FX, et al. Trends in pharmacists’ medication order review in French hospitals from 2006 to 2009: analysis of pharmacists’ interventions from the Act-IP (c) website observatory. J Clin Pharm Ther. 2015;40:32–40.
O’Sullivan D, O’Mahony D, O’Connor MN, Gallagher P, Cullinan S, O’Sullivan R, et al. The impact of a structured pharmacist intervention on the appropriateness of prescribing in older hospitalized patients. Drugs Aging. 2014;31:471–81.
Mekonnen AB, Yesuf EA, Odegard PS, Wega SS. Implementing ward based clinical pharmacy services in an Ethiopian university hospital. Pharm Pract. 2013;11:51–7.
Li X, Huo H, Kong W, Li F, Wang J. Physicians’ perceptions and attitudes toward clinical pharmacy services in urban general hospitals in China. Int J Clin Pharm. 2014;36:443–50.
Sabry N, Farid SF. The role of clinical pharmacists as perceived by Egyptian physicians. Int J Pharm Pract. 2014;22:354–9.
Awad A, Matowe L, Capps P. Medical doctors’ perceptions and expectations of the role of hospital pharmacists in Sudan. Pharm World Sci. 2007;29:557–64.
Willoch K, Blix HS, Pedersen-Bjergaard AM, Eek AK, Reikvam A. Handling drug-related problems in rehabilitation patients: a randomized study. Int J Clin Pharm. 2012;34:382–8.
Aburuz SM, Bulatova NR, Yousef AM, Al-Ghazawi MA, Alawwa IA, Al-Saleh A. Comprehensive assessment of treatment related problems in hospitalized medicine patients in Jordan. Int J Clin Pharm. 2011;33:501–11.
Khalili H, Farsaei S, Rezaee H, Dashti-Khavidaki S. Role of clinical pharmacists’ interventions in detection and prevention of medication errors in a medical ward. Int J Clin Pharm. 2011;33:281–4.
Lenssen R, Heidenreich A, Schulz JB, Trautwein C, Fitzner C, Jaehde U, et al. Analysis of drug-related problems in three departments of a German university hospital. Int J Clin Pharm. 2016;38:119–26.
Viktil KK, Blix HS, Reikvam A, Moger TA, Hjemaas BJ, Walseth EK, et al. Comparison of drug-related problems in different patient groups. Ann Pharmacother. 2004;38:942–8.
Bourne RS, Choo CL, Dorward BJ. Proactive clinical pharmacist interventions in critical care: effect of unit speciality and other factors. Int J Pharm Pract. 2014;22:146–54.
Geller AI, Nopkhun W, Dows-Martinez MN, Strasser DC. Polypharmacy and the role of physical medicine and rehabilitation. PM R. 2012;4:198–219.
Freeman CR, Cottrell WN, Kyle G, Williams ID, Nissen L. An evaluation of medication review reports across different settings. Int J Clin Pharm. 2013;35:5–13.
Bergkvist Christensen A, Holmbjer L, Midlov P, Hoglund P, Larsson L, Bondesson A, et al. The process of identifying, solving and preventing drug related problems in the LIMM-study. Int J Clin Pharm. 2011;33:1010–8.
Blix HS, Viktil KK, Moger TA, Reikvam A. Characteristics of drug-related problems discussed by hospital pharmacists in multidisciplinary teams. Pharm World Sci. 2006;28:152–8.
Bond CA, Raehl CL. Clinical pharmacy services, pharmacy staffing, and adverse drug reactions in United States hospitals. Pharmacotherapy. 2006;26:735–47.
Kaur S, Roberts JA, Roberts MS. Evaluation of medication-related problems in medication reviews: a comparative perspective. Ann Pharmacother. 2012;46:972–82.
Kwint HF, Faber A, Gussekloo J, Bouvy ML. Completeness of medication reviews provided by community pharmacists. J Clin Pharm Ther. 2014;39:248–52.
Kwint HF, Faber A, Gussekloo J, Bouvy ML. The contribution of patient interviews to the identification of drug-related problems in home medication review. J Clin Pharm Ther. 2012;37:674–80.
Bond CA, Raehl CL, Franke T. Interrelationships among mortality rates, drug costs, total cost of care, and length of stay in United States hospitals: summary and recommendations for clinical pharmacy services and staffing. Pharmacotherapy. 2001;21:129–41.
Bond CA, Raehl CL, Franke T. Medication errors in United States hospitals. Pharmacotherapy. 2001;21:1023–36.
Bond CA, Raehl CL, Franke T. Clinical pharmacy services, pharmacist staffing, and drug costs in United States hospitals. Pharmacotherapy. 1999;19:1354–62.
Langebrake C, Ihbe-Heffinger A, Leichenberg K, Kaden S, Kunkel M, Lueb M, et al. Nationwide evaluation of day-to-day clinical pharmacists’ interventions in German hospitals. Pharmacotherapy. 2015;35:370–9.
Klopfer JD, Einarson TR. Acceptance of pharmacists’ suggestions by prescribers: a literature review. Hosp Pharm. 1990;25(830–832):834–6.
Zhai XB, Gu ZC, Liu XY. Effectiveness of the clinical pharmacist in reducing mortality in hospitalized cardiac patients: a propensity score-matched analysis. Ther Clin Risk Manag. 2016;12:241–50.
Jiang SP, Chen J, Zhang XG, Lu XY, Zhao QW. Implementation of pharmacists’ interventions and assessment of medication errors in an intensive care unit of a Chinese tertiary hospital. Ther Clin Risk Manag. 2014;10:861–6.
Khdour MR, Alayasa KS, Alshahed QN, Hawwa AF. Physicians’ perceptions, attitudes and expectations regarding the role of hospital-based pharmacists in the West Bank, Palestine. Int J Pharm Pract. 2013;21:178–84.
Tahaineh LM, Wazaify M, Albsoul-Younes A, Khader Y, Zaidan M. Perceptions, experiences, and expectations of physicians in hospital settings in Jordan regarding the role of the pharmacist. Res Soc Adm Pharm. 2009;5:63–70.
Fahmy SA, Rasool BK, Abdu S. Health-care professionals’ perceptions and expectations of pharmacists’ role in the emergency department, United Arab emirates. East Mediterr Health J. 2013;19:794–801.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
This work was conducted as a part of the project No. 175023 funded by the Ministry of Education, Science and Technological Development, Belgrade, Republic of Serbia.
Conflicts of interest
The authors declared no conflicts of interest with respect to the research, authorship, and/or publication of this article.
Rights and permissions
About this article
Cite this article
Ljubojević, G., Miljković, B., Bućma, T. et al. Problems, interventions, and their outcomes during the routine work of hospital pharmacists in Bosnia and Herzegovina. Int J Clin Pharm 39, 743–749 (2017). https://doi.org/10.1007/s11096-017-0491-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11096-017-0491-x