Role of the hospital pharmacy and therapeutics committee in detecting and regulating off-label drug use
We have read the article published by Durán-García et al.  and would like to congratulate the authors on their work. Moreover, based on our own experience, we would also like to highlight the importance of the role of the Pharmacy and Therapeutics Committee in detecting and regulating the “off-label” drug use in hospitals.
Prescription-indication studies can be used to detect if medication is being used in ways other than those authorised by the drug regulatory agencies. This non-approved use is called “off-label” drug use . Our work area focuses on cytostatic drugs, and we know that the “off-label” use of these drugs become a common practice in some hospitals [3, 4, 5]. For example, Conde-García M et al.  found that Rituximab was used to treat unauthorised diagnoses (18 diagnoses) in 37.1% of patients between 2003 and 2007. Additionally, Rituximab was used in unauthorised chemotherapy plans (use with other cytostatic drugs) and lines of treatment (order of...
KeywordsTrastuzumab Scientific Evidence Follicular Lymphoma Hospital Pharmacy Pharmacy Service
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