Abstract
Objective Inappropriate use of antibacterial agents may lead to drug wastage and potential therapeutic failures in the future. The objective of this study was to investigate the extent of storage, and wastage of antibacterial agents in households in Palestine. Method This was a cross sectional, questionnaire-based study of households in northern Palestine. Any antibacterial agents present in the surveyed households were investigated and family members were interviewed. Main outcome measure Number and type of antibacterial agents stored in each household. Results The total number of antibacterial agents in the 465 surveyed households was 641, constituting 11.3% of the total stored medications. The average number of antibacterial agents was 1.4 ± 1.74 per household. The most common antibacterial agents encountered were amoxicillin (29.5%) and amoxicillin/clavulanic acid (11.6%). Family size (P < 0.001), total number of stored medications (P < 0.001), and presence of elderly residents (>65 years) (P < 0.001) were significantly associated with the presence of antibacterial agents. Furthermore, the level of parental education was significantly and positively (P = 0.009, r = 0.128; P = 0.013, r = 0.122 for father and mother respectively) correlated with the number of antibacterial agents found in the households. More than one-third (37.4%) of antibacterial agents were stored within the reach of children. Wasted antibacterial agents, defined as those which had expired or those with no clear expiry date were 16.4 and 10.1%, respectively. The percentage of antibacterial agents that were not currently in use was 69.3%. Estimated total value of antibacterial agents found in the study was $4,769, approximately $11.5 per household. The total wastage of antibacterial agents was valued at $2,790, approximately $6.7 per household. Conclusion Antibacterial agents were commonly encountered in Palestinian households, and a relatively large percentage was being wasted.
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References
Palestinian Central Bureau of Statistics. Palestinians in numbers, 2007. May, 2008.
Giacaman R, Abdul-Rahim HF, Wick L. Health sector reform in the occupied Palestinian Territory (OPT): targeting the forest or the trees? Health Policy Plan. 2003;18:59–67.
DFID. West Bank and Gaza health sector expenditure review, 2006. London: Department for International Development; 2006. http://www.opml.co.uk/policy_areas/public_financial_management/palestine_health_per.html.
Sawalha AF, Sweileh WM, Zyoud SH, Al-Jabi SW, Bani Shamseh FF, Odah AA. Analysis of prescriptions dispensed at community pharmacies in Palestine. East Mediterr Health J. 2010 (in press).
Bojalil R, Calva JJ. Antibiotic misuse in diarrhea. A household survey in a Mexican community. J Clin Epidemiol. 1994;47(2):147–56.
Bronzwaer SL, Cars O, Buchholz U, Mölstad S, Goettsch W, Veldhuijzen IK, Kool JL, Sprenger MJ, Degener JE, European Antimicrobial Resistance Surveillance System. A European study on the relationship between antimicrobial use and antimicrobial resistance. Emerg Infect Dis. 2002;8(3):278–82.
Goossens H, Ferech M, Vander Stichele R, Elseviers M. Outpatient antibiotic use in Europe and association with resistance: cross-national database study. Lancet. 2005;365(9459):579–87.
Okumura J, Wakai S, Umenai T. Drug utilisation and self-medication in rural communities in Vietnam. Soc Sci Med. 2002;54(12):1875–86.
Thomas JK, Forrest A, Bhavnani SM, Hyatt JM, Cheng A, Ballow CH, Schentag JJ. Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy. Antimicrob Agents Chemother. 1998;42:521–7.
Sawalha AF. Self-medication with antibiotics: a study in Palestine. Int J Risk Saf Med. 2008;20(4):213–22.
Orero A, González J, Prieto J. Antibiotics in Spanish households medical and socioeconomic implications. URANO Study Group. Med Clin (Barc). 1997;109(20):782–5.
Stratchounski LS, Andreeva IV, Ratchina SA, Galkin DV, Petrotchenkova NA, Demin AA, Kuzin VB, Kusnetsova ST, Likhatcheva RY, Nedogoda SV, Ortenberg EA, Belikov AS, Toropova IA. The inventory of antibiotics in Russian home medicine cabinets. Clin Infect Dis. 2003;37(4):498–505. Epub 2003 Aug 1.
De Bolle L, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: a source of potential health threats? Ann Pharmacother. 2008;42(4):572–9.
Yousif MA. In-home drug storage and utilization habits: a Sudanese study. East Mediterr Health J. 2002;8(2–3):422–31.
Abou-Auda HS. An economic assessment of the extent of medication use and wastage among families in Saudi Arabia and Arabian Gulf countries. Clin Ther. 2003;25(4):1276–92.
Zargarzadeh AH, Tavakoli N, Hassanzadeh A. A survey on the extent of medication storage and wastage in urban Iranian households. Clin Ther. 2005;27(6):970–8.
Sweileh WM. Self-medication and over-the-counter practices: a study in Palestine. J Al-Aqsa Univ. 2004;8:1–9.
Sweileh W, Arafat R. Attitudes toward medications: a pilot study in Palestine. Islam Univ J (Ser Nat Stud Eng). 2006;14(2):21–30.
Rice EC, Anderson WS, Clark GR. Reversible fanconi syndrome associated with degradation products of tetracycline. Case report. Clin Proc Child Hosp Dist Columbia. 1964;20:223–8.
Acknowledgement
The author would like to acknowledge An-Najah National University pharmacy students for their help in accomplishing this project.
Funding
No funding was available for this project.
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The authors declare no conflicts of interest directly relevant to the content of this manuscript.
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Appendix 1: The questionnaire used in the investigation of stored medications
Appendix 1: The questionnaire used in the investigation of stored medications
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1.
Name of the interviewee
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2.
Age of the interviewee
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3.
Education of the father
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(1)
College
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(2)
Third grade—High school
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(3)
Illiterate
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(1)
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4.
Education of the mother
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(1)
College
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(2)
Third grade—High school
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(3)
Illiterate
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(1)
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5.
Place of living
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(1)
City
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(2)
Village/suburbs
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(1)
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6.
Income
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(1)
High
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(2)
Middle
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(3)
Low
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(1)
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7.
Number of family members
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8.
Number of family members <6 years of age
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9.
Number of family members >65 years of age
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10.
Any member in the family with chronic disease?
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11.
If yes, what is the chronic disease
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12.
Any member in the family who works as a health care provider.
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13.
Is there a medical insurance for the family?
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14.
If yes, what type of insurance?
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15.
Fill in the following table for each medication stored at home
Brand name of the medication | |
Pharmaceutical dosage form | |
Quantity of the medication present | |
Who is using the medication now | |
Do you know the therapeutic use of the medication | |
Frequency of use of the medication | |
Expiration date of the medication | |
Is the medication in its original package? | |
Where the medication is stored | |
What is the source of the medication | |
Price of the medication |
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Sawalha, A. Extent of storage and wastage of antibacterial agents in Palestinian households. Pharm World Sci 32, 530–535 (2010). https://doi.org/10.1007/s11096-010-9404-y
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DOI: https://doi.org/10.1007/s11096-010-9404-y