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Nanoscaled Zinc Oxide Prepared by Mono-amino Acid Templated Assembly and Their Superior Biological Properties

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Abstract

Nanoscaled zinc oxide (ZnO) was synthesized via a benign mineralization reaction using mono-amino acid as templates. Characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy, it was found that the microstructure of as-prepared ZnO can be fine-tuned into olive-like and flake-like structures with leucine and histidine respectively. Otherwise, the photoluminescence (PL) results indicate that biomineralized ZnO nanoparticles show a potential application in the fields of optical devices. To further explore the biological performance of as-prepared ZnO nanoparticles, antibacterial activity tests against Staphylococcus aureus and Escherichia coli, and cytocompatibility on mouse MC3T3 cells were also investigated. The superior biological properties of these biomineralized ZnO together with their intrinsic photoluminescent properties open perspectives for the development of biomedical applications.

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Acknowledgements

This work was supported by the project of National Natural Science Foundation of China (No. 51701073), Natural Science Foundation of Hunan Province (No. 2018JJ3241), the Open Fund of the Guangdong Provincial Key Laboratory of Advanced Energy Storage Materials and the Hunan Key Laboratory of crop germplasm innovation and resource utilization foundation of Hunan Agricultural University under Project No. 50262.

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Authors and Affiliations

  1. Key Laboratory of Crop Epigenetic Regulation and Development in Hunan Province, Hunan Agricultural University, Changsha, 410128, China

    Chengfang Tan & Ying Ruan

  2. Hunan Engineering Center of Cell Mechanics Function Analysis, Hunan Agricultural University, Changsha, 410128, China

    Chengfang Tan, Zhiying Sun, Yisheng Cui & Gege Zuo

  3. School of Chemistry and Material Science, Hunan Agricultural University, Changsha, 410128, China

    Peng Yu & Hui Liu

  4. Guangdong Provincial Key Laboratory of Advanced Energy Storage Materials, South China University of Technology, Guangzhou, 510640, China

    Hui Liu

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  1. Chengfang Tan
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  2. Zhiying Sun
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Correspondence to Hui Liu.

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Tan, C., Sun, Z., Ruan, Y. et al. Nanoscaled Zinc Oxide Prepared by Mono-amino Acid Templated Assembly and Their Superior Biological Properties. J Clust Sci 33, 485–493 (2022). https://doi.org/10.1007/s10876-021-01986-w

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  • DOI: https://doi.org/10.1007/s10876-021-01986-w

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