Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives
Several new N-containing epiandrosterone derivatives modified by phenylacetic acid chloride were synthesized for biological activity studies. Compounds with antiviral activity were discovered among them and 3β-hydroxy-1′-aryl-3′-methyl-5′-androstano[17,16-d]pyrazolines prepared by us earlier.
Keywordsantiviral activity epiandrosterone modification phenylacetic acid hydrazones pyrazolines
The work was financially supported by the Shota Rustaveli National Science Foundation of Georgia (Grant No. YS-2016-51, Potential Bioactive Steroidal Nitrogen-containing Compounds).
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