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Selective reduction of N-nitroso aza-aliphatic cyclic compounds to the corresponding N-amino products using zinc dust in CO2–H2O medium

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Chemistry of Heterocyclic Compounds Aims and scope

A new method for reduction of N-nitroso aza-aliphatic cyclic compounds employing zinc in pressurized CO2–H2O medium has been developed. H2O and NH4Cl were used as hydrogen donors, and reduction was performed under environmentally benign conditions. The presented approach allowed to obtain the respective N-amino products selectively and in excellent yields (up to 97%).

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The authors are grateful to the Ministry of Education, ''Chunhui Projects'' project Z2016163) and the Scientific Research Foundation of the Education Department of Sichuan Province (project 12ZB128) for financial support.

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Authors and Affiliations

  1. School of Science, Xihua University, 999 Jin Zhou Rd, Chengdu, 610039, Jin niu District, China

    Weiqing Yang, Xiang Lu, Tingting Zhou, Yongjing Cao, Yuanyuan Zhang & Menglin Ma

  2. Key Laboratory of Green Chemistry and Technology, Faculty of Chemistry, Sichuan University, 24 South Section 1 Yihuan Rd, Chengdu, 610064, China

    Yuanyuan Zhang

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  1. Weiqing Yang
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  2. Xiang Lu
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  3. Tingting Zhou
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  4. Yongjing Cao
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  5. Yuanyuan Zhang
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  6. Menglin Ma
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Correspondence to Menglin Ma.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(8), 780–783

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Yang, W., Lu, X., Zhou, T. et al. Selective reduction of N-nitroso aza-aliphatic cyclic compounds to the corresponding N-amino products using zinc dust in CO2–H2O medium. Chem Heterocycl Comp 54, 780–783 (2018). https://doi.org/10.1007/s10593-018-2349-0

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  • DOI: https://doi.org/10.1007/s10593-018-2349-0

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