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Heterocyclic Analogs of 5,12-Naphthacenequinone 14*. Synthesis of naphtho[2,3-f]indole-3-carboxylic Acid Derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

3-carboxylate by using vicarious substitution of hydrogen, followed by intramolecular reductive heterocyclization. Some chemical properties of the target compound were characterized. As observed for the first time in the series of linear hetaryl-fused anthraquinones, the alkylation of hydroxy groups in naphtho[2,3-f]indole-5,10-diones gave not only 4,11-dialkoxy derivatives, but also the isomeric 5,10-dialkoxy derivatives of naphtho[2,3-f]indole-4,11-dione.

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Authors and Affiliations

  1. Gause Institute of New Antibiotics, 11 B. Pirogovskaya St., Moscow, 119021, Russia

    Alexander S. Tikhomirov, Valeriya A. Litvinova, Yury N. Luzikov, Alexander M. Korolev & Andrey E. Shchekotikhin

  2. D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow, 125190, Russia

    Alexander S. Tikhomirov, Valeriya A. Litvinova, Yuri B. Sinkevich & Andrey E. Shchekotikhin

Authors
  1. Alexander S. Tikhomirov
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  2. Valeriya A. Litvinova
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  3. Yury N. Luzikov
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  4. Alexander M. Korolev
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  5. Yuri B. Sinkevich
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  6. Andrey E. Shchekotikhin
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Correspondence to Andrey E. Shchekotikhin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(10), 1072–1079

* For Communication 13, see1.

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Tikhomirov, A.S., Litvinova, V.A., Luzikov, Y.N. et al. Heterocyclic Analogs of 5,12-Naphthacenequinone 14*. Synthesis of naphtho[2,3-f]indole-3-carboxylic Acid Derivatives. Chem Heterocycl Comp 53, 1072–1079 (2017). https://doi.org/10.1007/s10593-017-2173-y

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  • DOI: https://doi.org/10.1007/s10593-017-2173-y

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