The reaction of the analogs of natural 3-arylbenzopyran-2-ones with electrophilic reagents of aminal structure was studied. Substituted 8-aminomethyl-3-aryl-7-hydroxycoumarins were synthesized. The optimum conditions were determined for the production of 9-alkyl- and 9-(het)arylmethyl derivatives of 3-aryl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one in the series of analogs of natural 3-arylbenzopyran-2-ones.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 672-678, May, 2010.
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Bondarenko, S.P., Frasinyuk, M.S. & Khilya, V.P. Aminomethylation of 3-aryl-7-hydroxycoumarins. Chem Heterocycl Comp 46, 529–535 (2010). https://doi.org/10.1007/s10593-010-0541-y
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DOI: https://doi.org/10.1007/s10593-010-0541-y