(Z)-4-Aryl-2-[3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylamino]-4-oxobuten-2-oic acids, which exist in the enamino keto form in solutions, were synthesized by the action of ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate on 4-aryl-2-hydroxy-4-oxobuten-2-oic acids. Under the influence of acetic anhydride the obtained acids undergo cyclization to ethyl 2-(5-aryl-2-oxofuran-3(2H)-ylideneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylates.
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*For Communication 2, see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 832-835, June, 2009.
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Shipilovskikh, S.A., Rubtsov, A.E. & Zalesov, V.V. Chemistry of iminofurans 3. *Synthesis and intramolecular cyclization of (Z)-4-aryl- 2-[3-(ethoxycarbonyl)-4,5,6,7-tetra- hydrobenzo[b]thiophen-2-ylamino]- 4-oxobuten-2-oic acids. Chem Heterocycl Comp 45, 658–661 (2009). https://doi.org/10.1007/s10593-009-0334-3
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DOI: https://doi.org/10.1007/s10593-009-0334-3