Skip to main content
SpringerLink
Log in

RETRACTED ARTICLE: Primary Draining Vein Stenting for Obstructive Total Anomalous Pulmonary Venous Connection in Neonates with Right Atrial Isomerism and Functional Single Ventricle Improves Outcome

  • Original Article
  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

This article was retracted on 19 June 2019

This article has been updated

Abstract

For neonates with right atrial isomerism (RAI), functional single ventricle (f-SV), and obstructive total anomalous pulmonary venous connection (TAPVC), primary TAPVC repair (TAPVCR) has a poor outcome. At our hospital, the survival rate at 1 year of such neonates undergoing primary TAPVCR between 1999 and 2010 (TAPVCR group) was 30% (3/10). Most deceased cases suffered from capillary leak syndrome and unstable pulmonary resistance after the surgeries. We sought to determine whether less invasive primary draining vein stenting (DVS) improved the outcome of these neonates. We investigated outcomes in consecutive nine such neonates (median gestational age 38 weeks, birth weight 2.8 kg, females 4) who underwent primary DVS with 6-mm-diameter Palmaz® Genesis® stents at our hospital between 2007 and 2017 (DVS group). Eight patients underwent subsequent surgeries to adjust the pulmonary flow after decreased pulmonary resistance. The survival rate at 1 year after the first interventions in the DVS group improved to 77% (7/9), although there was a difference between the interventional eras of the two groups. Of the seven patients who underwent multiple stent redilations with a larger balloon or additional stenting in other sites until the next stage of surgery at a median age of 8 months, four received a bidirectional Glenn (BDG) shunt and TAPVCR and three underwent TAPVCR, with two of those cases reaching BDG. Less invasive primary DVS improved the outcome of neonates with RAI, f-SV, and obstructive TAPVC, with many reaching BDG. Patient selection to advance toward Fontan is thought to further improve the outcome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Change history

  • 19 June 2019

    The authors have retracted this article [1] because, contrary to the statement in the article, this research did not obtain ethics approval from the National Cerebral and Cardiovascular Center Institutional Review Board prior to submission of the manuscript to Pediatric Cardiology. All authors agree to this retraction.

  • 19 June 2019

    The authors have retracted this article [1] because, contrary to the statement in the article, this research did not obtain ethics approval from the National Cerebral and Cardiovascular Center Institutional Review Board prior to submission of the manuscript to Pediatric Cardiology. All authors agree to this retraction.

  • 19 June 2019

    The authors have retracted this article [1] because, contrary to the statement in the article, this research did not obtain ethics approval from the National Cerebral and Cardiovascular Center Institutional Review Board prior to submission of the manuscript to Pediatric Cardiology. All authors agree to this retraction.

References

  1. Anagnostopoulos PV, Pearl JM, Octave C, Cohen M, Gruessner A, Wintering E, Teodori MF (2009) Improved current era outcomes in patients with heterotaxy syndromes. Eur J Cardiothorac Surg 35:871–877

    Article  Google Scholar 

  2. Ota N, Fujimoto Y, Murata M, Tosaka Y, Ide Y, Tachi M, Ito H, Sugimoto A, Sakamoto K (2012) Improving outcomes of the surgical management of right atrial isomerism. Ann Thorac Surg 93:832–838

    Article  Google Scholar 

  3. Serraf A, Bensari N, Houyel L, Capderou A, Roussin R, Lebret E, Ly M, Belli E (2010) Surgical management of congenital heart defects associated with heterotaxy syndrome. Eur J Cardiothorac Surg 38:721–727

    Article  Google Scholar 

  4. Khan MS, Bryant R 3rd, Kim SH, Hill KD, Jacobs JP, Jacobs ML, Pasquali SK, Morales DL (2015) Contemporary outcomes of surgical repair of total anomalous pulmonary venous connection in patients with heterotaxy syndrome. Ann Thorac Surg 99:2134–2139

    Article  Google Scholar 

  5. Yun TJ, Al-Radi OO, Adatia I, Caldarone CA, Coles JG, Williams WG, Smallhorn J, Van Arsdell GS (2006) Contemporary management of right atrial isomerism: effect of evolving therapeutic strategies. J Thorac Cardiovasc Surg 131:1108–1113

    Article  Google Scholar 

  6. Hoashi T, Kagisaki K, Oda T, Kitano M, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H (2013) Long-term results of treatments for functional single ventricle associated with extracardiac type total anomalous pulmonary venous connection. Eur J Cardiothorac Surg 43:965–970

    Article  Google Scholar 

  7. Cheung YF, Cheng VY, Chau AK, Chiu CS, Yung TC, Leung MP (2002) Outcome of infants with right atrial isomerism: is prognosis better with normal pulmonary venous drainage? Heart 87:146–152

    Article  CAS  Google Scholar 

  8. Foerster SR, Gauvreau K, McElhinney DB, Geva T (2008) Importance of totally anomalous pulmonary venous connection and postoperative pulmonary vein stenosis in outcomes of heterotaxy syndrome. Pediatr Cardiol 29:536–544

    Article  Google Scholar 

  9. St Louis JD, McCracken CE, Turk EM, Hancock HS, Menk JS, Harvey BA, Vinocur JM, Oster ME, Moller JH, Spector LG, Kochilas LK (2018) Long-term transplant-free survival after repair of total anomalous pulmonary venous connection. Ann Thorac Surg 105:186–192

    Article  Google Scholar 

  10. Lodge AJ, Rychik J, Nicolson SC, Ittenbach RF, Spray TL, Gaynor JW (2004) Improving outcomes in functional single ventricle and total anomalous pulmonary venous connection. Ann Thorac Surg 78:1688–1695

    Article  Google Scholar 

  11. Morales DL, Braud BE, Booth JH, Graves DE, Heinle JS, McKenzie ED, Fraser CD Jr (2006) Heterotaxy patients with total anomalous pulmonary venous return: improving surgical results. Ann Thorac Surg 82:1621–1627

    Article  Google Scholar 

  12. Jacobs JP, Pasquali SK, Morales DL, Jacobs ML, Mavroudis C, Chai PJ, Tchervenkov CI, Lacour-Gayet FG, Walters H 3rd, Quintessenza JA (2011) Heterotaxy: lessons learned about patterns of practice and outcomes from the congenital heart surgery database of the society of thoracic surgeons. World J Pediatr Congenit Heart Surg 2:278–286

    Article  Google Scholar 

  13. Nakata T, Fujimoto Y, Hirose K, Osaki M, Tosaka Y, Ide Y, Tachi M, Sakamoto K (2009) Functional single ventricle with extracardiac total anomalous pulmonary venous connection. Eur J Cardiothorac Surg 36:49–56

    Article  Google Scholar 

  14. Kitano M, Yazaki S, Kagisaki K, Kurosaki K (2009) Primary palliative stenting against obstructive mixed-type total anomalous pulmonary venous connection associated with right atrial isomerism. J Interv Cardiol 22:404–409

    Article  Google Scholar 

  15. Wong DT, Yoo SJ, Lee KJ (2008) Implantation of drug-eluting stents for relief of obstructed infra-cardiac totally anomalous pulmonary venous connection in isomerism of the right atrial appendages. Cardiol Young 18:628–630

    Article  Google Scholar 

  16. Jhang WK, Chang YJ, Park CS, Oh YM, Kim YH, Yun TJ (2008) Hybrid palliation for right atrial isomerism associated with obstructive total anomalous pulmonary venous drainage. Interact Cardiovasc Thorac Surg 7:282–284

    Article  Google Scholar 

  17. Kobayashi D, Forbes TJ, Aggarwal S (2013) Palliative stent placement in vertical vein in a 1.4 kg infant with obstructed supracardiac total anomalous pulmonary venous connection. Catheter Cardiovasc Interv 82:574–580

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

    Masataka Kitano, Kazuto Fujimoto, Akira Miyake, Ken-ichi Kurosaki & Isao Shiraishi

  2. Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

    Takaya Hoashi, Takashi Kakuta & Hazime Ichikawa

Authors
  1. Masataka Kitano
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takaya Hoashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Takashi Kakuta
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kazuto Fujimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Akira Miyake
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ken-ichi Kurosaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Hazime Ichikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Isao Shiraishi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Masataka Kitano.

Ethics declarations

Conflict of interest

The authors have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

The ethical standards of the institutional research committee granted permission to access and analyze the data with a waiver of informed consent because this is a retrospective analysis of the collected data.

Additional information

The authors have retracted this article because, contrary to the statement in the article, this research did not obtain ethics approval from the National Cerebral and Cardiovascular Center Institutional Review Board prior to submission of the manuscript to Pediatric Cardiology. All authors agree to this retraction.

Appendix

Appendix

See Figs. 4, 5 and Tables 7, 8, 9.

Fig. 4
figure 4

Outcomes of the two groups after the first interventions

Full size image
Fig. 5
figure 5

Survival rates in the two groups after the first interventions

Full size image
Table 7 Patients’ characteristics in the two groups
Full size table
Table 8 The first-stage interventions and patients’ conditions before them in the two groups
Full size table
Table 9 Clinical courses after the initial surgeries in the two groups
Full size table

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kitano, M., Hoashi, T., Kakuta, T. et al. RETRACTED ARTICLE: Primary Draining Vein Stenting for Obstructive Total Anomalous Pulmonary Venous Connection in Neonates with Right Atrial Isomerism and Functional Single Ventricle Improves Outcome. Pediatr Cardiol 39, 1355–1365 (2018). https://doi.org/10.1007/s00246-018-1902-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00246-018-1902-z

Keywords

Search

Navigation