, Volume 5, Issue 4, pp 74–84 | Cite as

Mitochondria can power cells to life and death

Role of mitochondria in apoptosis
  • Nand K. Sah
  • Tarvinder K. Taneja
  • Seyed E. Hasnain
General Article


Mitochondria serve as power houses of cells but they also possess ‘covered’ knives to kill the cells. A number of intrinsic and extrinsic factors exist which regulate cell killing by mitochondria. Caspases are comparable to a surgeon’s knife, which can be used to sculpt organisms, get rid of wayward, redundant and incorrigibly damaged cells, but can spell doom if not controlled properly.


African Swine Fever African Swine Fever Virus Apoptotic Machinery Power House Growth Factor Withdrawal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Suggested Reading

  1. [1]
    S P Modak and F J Bollum,Exp. Cell Res., 62, 421–412, 1970.CrossRefGoogle Scholar
  2. [2]
    T Ramasarma, B K A Rasheed, S Vijaya, R S Purnam, V Shivaswamy, A S Gaikwad and C K R Kurup,Indian Journal of Biochemistry and Biophysics, 29, 173–178, 1992.Google Scholar
  3. [3]
    D R Green,Cell, 94, 695–698, 1998.CrossRefGoogle Scholar
  4. [4]
    Nand Shah, Tarvinder, Taneja K, Niteen Pathak, Rasheedunnisa Begum, Mohammad Athar and Seyed E Hasnain,Proc. Natl. Acad. Sci.,USA, 96, 4838–4843, 1999.CrossRefGoogle Scholar

Copyright information

© Indian Academy of Sciences 2000

Authors and Affiliations

  • Nand K. Sah
    • 1
  • Tarvinder K. Taneja
    • 1
    • 3
  • Seyed E. Hasnain
    • 1
    • 2
  1. 1.Eukaryotic Gene Expression LaboratoryNational Institute of ImmunologyNew DelhiIndia
  2. 2.Laboratory of Molecular & Cellular BiologyCDFDHyderabadIndia
  3. 3.Department of Medical Elementology & ToxicologyJamia HamdardNew DelhiIndia

Personalised recommendations