, Volume 5, Issue 4, pp 74–84 | Cite as

Mitochondria can power cells to life and death

Role of mitochondria in apoptosis
  • Nand K. Sah
  • Tarvinder K. Taneja
  • Seyed E. Hasnain
General Article


Mitochondria serve as power houses of cells but they also possess ‘covered’ knives to kill the cells. A number of intrinsic and extrinsic factors exist which regulate cell killing by mitochondria. Caspases are comparable to a surgeon’s knife, which can be used to sculpt organisms, get rid of wayward, redundant and incorrigibly damaged cells, but can spell doom if not controlled properly.


African Swine Fever African Swine Fever Virus Apoptotic Machinery Power House Growth Factor Withdrawal 


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Copyright information

© Indian Academy of Sciences 2000

Authors and Affiliations

  • Nand K. Sah
    • 1
  • Tarvinder K. Taneja
    • 1
    • 3
  • Seyed E. Hasnain
    • 1
    • 2
  1. 1.Eukaryotic Gene Expression LaboratoryNational Institute of ImmunologyNew DelhiIndia
  2. 2.Laboratory of Molecular & Cellular BiologyCDFDHyderabadIndia
  3. 3.Department of Medical Elementology & ToxicologyJamia HamdardNew DelhiIndia

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