The Indian Journal of Pediatrics

, Volume 55, Issue 2, pp 183–190 | Cite as

Escherichia coli that cause diarrhea

  • Myron M. Levine
  • Pablo Vial
Symposium : Infectious diseases


Diarrhea Hemolytic Uremic Syndrome Diarrheal Disease Enteric Pathogen Virulence Property 
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  1. 1.
    Levine MM.Escherichia coli that cause diar-rhea: enterotoxigenic.enteropathogenic, enter-oinvasive, enterohemorrhagic, and entero-adherent.J Infect Dis 1987;155 : 377–389PubMedGoogle Scholar
  2. 2.
    Kauffmann F. The serology of the coli group,J Immunol 1947;57: 71–100PubMedGoogle Scholar
  3. 3.
    Neter E, Westphal O, Luderitz O, Needell MH. Demonstration of antibodies against enteropathogenicEscherichia coli in sera of children of various ages.Pediatrics 1955;16:801–7PubMedGoogle Scholar
  4. 4.
    Levine MM, Edelman R. EnteropathogenicEscherichia coli of classical serotypes asso-ciated with infant diarrhea-epidemiology and pathogenesis.Epidemiol Rev 1984;6: 31–51PubMedGoogle Scholar
  5. 5.
    Ewing WH, Davis BR, Montague TS. Studies on the occurrence ofEscherichia coli sero-type associated with diarrheal disease. Atlanta, GA: US Department of Health, Education and Welfare, Public Health Service, Com-municable Disease Centre, 1963Google Scholar
  6. 6.
    Taylor J. Host specificity and enteropatho-genicity ofEscherichia coli.J Appl Bacteriol 1961;3: 316–25Google Scholar
  7. 7.
    Levine MM, Bergguist EJ, Nalin DR, Water-man DH, Hornick RB, Young CR, Sotman S, Rowe B.Escherichia coli strains that cause diarrhea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive.Lancet 1978;I: 1119–22.CrossRefGoogle Scholar
  8. 8.
    Cravioto A, Gross RJ, Scotland SM, Rowe B. An adhesive factor found in strains ofEscherichia coli belonging to the traditional infantile enteropathogenic serotypes.Curr Microbiol 1979;3: 95–9CrossRefGoogle Scholar
  9. 9.
    Scaletsky ICA, Silva MLM, Trabulsi LR. Distinctive patterns of adherence of entero-pathogenicEscherichia coli to HeLa cells.Infect Immun 1984;45: 534–6PubMedGoogle Scholar
  10. 10.
    Nataro JP, Scaletsky ICA, Kaper JB, Levine MM, Trabulsi LR. Plasmid-mediated factors conferring diffuse and localized adherence of enteropathogenicEscherichia coli.Infect Immu 1985;48: 378–83Google Scholar
  11. 11.
    Nataro JP, Baldini MM, Kaper JB, Black RE, Levine MM. Detection of an adherence factor of enteropathogenicEscherichia coli with a DNA probe.J Infect Dis 1985;152: 560–5PubMedGoogle Scholar
  12. 12.
    Nataro JP, Kaper JB, Robins-Browne R, Prado V, Vial P, Levine MM. Patterns of adherence of diarrheagenicEscherichia coli to HEp-2 cells.J Pediatr Infect Dis 1987 (in press)Google Scholar
  13. 13.
    Levine MM, Nataro JP, Baldini MM, Kaper JB, Black RE, Clements ML, O’Brien AD. The diarrheal response of humans to some classical serotype enteropathogenicEscherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor.J Infect Dis 1985;152: 550–9PubMedGoogle Scholar
  14. 14.
    Marques LRM, Moore MA, Wells J, Wachs-muth IK, O’Brien AD. Production of Shiga-like toxin byEscherichia coli.J Infect Dis 1986;154: 338–41PubMedGoogle Scholar
  15. 15.
    Cleary TG, Mathewson JJ, Fan’s E, Pickering LK. Shiga-like cytotoxin production by entero-pathogenicEscherichia coli serogroups.Infect Immun 1985;47: 335–7PubMedGoogle Scholar
  16. 16.
    Toledo MRF, Alvariza MDB, Murahovschi J, Ramos SRTS, Trabulsi LR. EnteropathogenicEscherichia coli serotypes and endemic diarrhea in infants.Infect Immun 1983;39: 586–9PubMedGoogle Scholar
  17. 17.
    Prado V, Braun S, Bosch P, Bercovich M, Reyes M, Sawada M. Analisis deEscherichia coli enteropatogeno clasico (E.C.E.P.) como causa endemica de diarrea aguda en ninos Chilenos.Rev Chil Pediatr 1984;55: 171–5PubMedGoogle Scholar
  18. 18.
    Gorbach SL, Banwell JG, Chatterjee BD, Jacobs B, Sack RB. Acute undifferentiated diarrhea in the tropics: I. Alterations in intestinal microflora.J Clin Invest 1971;50 : 881–9PubMedCrossRefGoogle Scholar
  19. 19.
    Sack RB. EnterotoxigenicEscherichia coli: Identification and characterization.J Infect Dis 1980;142: 279–86PubMedGoogle Scholar
  20. 20.
    Black RE, Brown KH, Becker S, Alim Abdul ARM, Huq I. Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh. II. Incidence of diarrhea and association with well known pathogens.Am J Epidemol 1982;115: 315–24Google Scholar
  21. 21.
    Black RE, Merson MH, Huq I, Alim ARMA, Yunus M. Incidence and severity of rotavirus andEscherichia coli diarrhoeal in rural Bangladesh.Lancet 1981 ;i: 141–3CrossRefGoogle Scholar
  22. 22.
    Black RE, Brown KH, Becker S, Alim AR, Huq I. Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh. II. Incidence of diarrhea and association with known pathogens.Am J Epidemiol 1982;115: 315–24PubMedGoogle Scholar
  23. 23.
    Merson JH, Moms GK, Sack DA, Wells JG, Feeley JC, Sack RB, Creech WB, Kapikian AZ, Gangarosa EJ. Travelers diarrhea in Mexico: a prospective study of physicians and family members attending a congressNew Engl J Med 1976;294 : 1299–1305PubMedCrossRefGoogle Scholar
  24. 24.
    Sack DA, Kaminsky DC, Sack RB, Itotia JN, Arthur RR, Kapikian AZ, Orskov F, Orskov I. Prophylactic doxycycline for tra-verlers’ diarrhea.New Engl J Med 1978;298: 758–63PubMedCrossRefGoogle Scholar
  25. 25.
    DuPont HL, Olarte J, Evans DG, Pickering LK, Galindo E, Evans DJ. Comparative susceptibility of Latin American and United States students to enteric pathogens.New Engl J Med 1976;295: 1520–1PubMedCrossRefGoogle Scholar
  26. 26.
    Levine MM, Kaper JB, Black RE, Clements ML. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development.Microbiol Rev 1983;47: 510–50PubMedGoogle Scholar
  27. 27.
    Ristaino PA, Levine MM, Young CR. Im-proved GMI-enzyme linked immunoabsor-bent assay for detection ofEscherichia coli heatlabile enterotoxin.J Clin Microbiol 1983;18: 808–815PubMedGoogle Scholar
  28. 28.
    Honda T, Taga S, Takeda Y, Miwatani T. Modified Elek test for detection of heat-labile enterotoxin of enterotoxigenicEscherichia coli.J Clin Microbiol 1981 ;13: 1–5PubMedGoogle Scholar
  29. 29.
    Lanata CF, Kaper JB, Baldini MM, Black RE, Levine MM. Sensitivity and specificity of DNA probes with the stool blot technique for detection ofEscherichia coli enterotoxins.J Infect Dis 1985;152: 1087–1090PubMedGoogle Scholar
  30. 30.
    Thompson MR, Jordan RL, Luttrell MA, Brandwein H, Kaper JB, Levine MM, Gian-nella RA. Blinded two-laboratory comparative analysis ofEscherichia coli heat-stable entero-toxin production by using monoclonal anti-body, enzyme-linked immunosorbent assay, radioimmunoassay, suckling mouse assay, and gene probes.J Clin Microbiol 1986;24: 753–758PubMedGoogle Scholar
  31. 31.
    Dean AG, Ching Y-C, Williams RG, Harden LB. Test forEscherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.J Infect Dis 1972;125 :407–411PubMedGoogle Scholar
  32. 32.
    Toledo MRF, Trabulsi L. Correlation bet-ween biochemical and serological characteris-ticsof Escherichia coli and results of the Sereny test.J Clin Microbiol 1983 ;17: 419–21PubMedGoogle Scholar
  33. 33.
    Pal T, Pacsa AS, Emody L, Voros S. Selley. Modified enzyme-linked immunosorbent assay for detecting enteroinvasiveEscherichia coli and virulentShigella species.J Clin Microbiol 1985;21: 415–8PubMedGoogle Scholar
  34. 34.
    Wood PK, Morris Jr JG, Small PC, Sethabutr O, Trabulsi L, Kaper J. Comparison of DNA probes with the Sereny test in the identification of invasive strains of Shigella andEscherichia coli.J Clin Microbiol 1986;24: 498–500PubMedGoogle Scholar
  35. 35.
    Riley LW, Remis RS, Helgerson SD, MoGee HB, Wells JG, Davis BR, Hebert RJ, Olcott ES, Johnson LM, Hargrett NT, Blake PA, Cohen ML. Hemorrhagic colitis associated with a rareEscherichia coli serotype.New Engl J Med 1982;308: 681–5CrossRefGoogle Scholar
  36. 36.
    Levine MM, Xu J-G, Kaper JB, Lior H, Prado V, Tall B, Nataro JP, Karch H, Wach-smuth IK. A DNA probe to identify entero-hemorrhagicEscherichia coli of 0157 : H7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome.J Infect Dis 1987 :156 (in press)Google Scholar
  37. 37.
    Karch H, Heeseman J, Laufs R, O’Brien AD, Tacket CO, Levine MM. A plasmid of enterohemorrhagicEscherichia coli 0157 : H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells. Infect Immun 55 : 455–461Google Scholar
  38. 38.
    Tzipori S, Wachsmuth KI, Chapman C, Birner R, Brittingham J, Jackson C, Hogg J. Studies on the pathogenesis of haemorrhagic colitis caused byEscherichia coli 0157: H7 in gnotobiotic piglets.J Infect Dis 1986;154 : 712–716PubMedGoogle Scholar
  39. 39.
    Vial P, Prado V, Robins-Browne R, Lior H, Maneval D, Tall B, Kaper J, Nataro J, Levine M. AutoagglutinatingE. Coli (AutEC) —A new enteric pathogen. Abstract, 28th Interscience Conference on Antimicrobial Agents and Chemotherapy, New York October, 1987.Google Scholar
  40. 40.
    Mathewson JJ, Johnson PC, DuPont HL, Satterwhite TK, Winsor DK. Pathogenicity of enteroadherentEscherichia coli in adult volunteers.J Infect Dis 1986;154: 524–7PubMedGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 1988

Authors and Affiliations

  • Myron M. Levine
    • 1
  • Pablo Vial
    • 1
  1. 1.The Division of Infectious Disease and Tropical Pediatrics, Department of PediatricsUniversity of Maryland School of MedicineBaltimoreUSA

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