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The essential oil of Apium graveolens var. secalinum and its cercaricidal activity

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Abstract

The composition of the essential oil of the fresh aerial parts ofApium graveolens var.secalinum at its flowering stage, obtained from three different locations in Egypt, was investigated. The identification of the components of this oil was carried out by means of analytical GC and GC-MS. The main components in the oil are: α- and Β-pinene, myrcene, limonene,cis-Β-ocimene, γ-terpinene,cis-allo-ocimene,trans-farnesene, humulene, apiol, Β-selinene, senkyunolide and neocnidilide. Data concerning the relative concentrations of the main components of the different celery oil samples are given. The cercaricidal effect of the essential oil has been examined on cercariae, being one of the stages in the life cycles ofSchistosoma mansoni, which causes schistosomiasis. The essential oil showed in addition to a cercaricidal effect also a chemotactic effect.

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References

  1. Wagner H. Pharmazeutisch Biologie 2. Drogen und ihre Inhaltstoffe. 3. Auflage. Stuttgart: G. Fischer Verlag, 1985:83.

    Google Scholar 

  2. Reynolds JEF, ed. Martindale. The Extra Pharmacopoeia. 28th ed. London: The Pharmaceutical Press, 1982:673.

    Google Scholar 

  3. Hartwell JL. Plants used against cancer. A survey. Lloydia 1971;34:310–61.

    PubMed  Google Scholar 

  4. Johnson AE, Nursten HE, Williams AA. Vegetable volatiles: a survey of components identified: part II. Chem Ind 1971:1212–24.

  5. Fehr D. Untersuchung über Aromastoffe von Sellerie (Apium graveolens L.). Pharmazie 1979;34:658–62/1981;36:374–6.

    Google Scholar 

  6. Kloos H, McCullough FS. Plant Molluscicides. Planta Med 1982;46:195–209.

    Google Scholar 

  7. Marston A, Hostettmann K. Plant Molluscicides. Phytochemistry 1985;24:639–52.

    Google Scholar 

  8. Warren KS, Peters PA. Cercariae ofSchistosoma mansoni and plants, attempt to penetratePhaseolus vulgaris andHedychium coronarium. Nature 1968;217:647–50.

    PubMed  Google Scholar 

  9. Farnsworth NR, Cordeil GS. A review of some biologically active compounds isolated from plants as reported in the 1974—1975 literature. Lloydia 1976;39:420–55.

    PubMed  Google Scholar 

  10. Frischkorn CG. Cercaricidal activity of some essential oil plants from Brazil. Naturwissenschaften 1978;65:480–3.

    PubMed  Google Scholar 

  11. Graham K, Graham EA, Towers GHN. Cercaricidal activity of phenylheptatriyne and atertienyl, naturally occurring compounds in species of Asteridaceae and Compositae. Can J Zool 1980;58:1955–7.

    Google Scholar 

  12. Baker PM, Fortes CC, Fortes EG, et al. Chemoprophylactic agents in schistosomiasis: eremanthine, costunolide, α-cyclocostunolide and bisabolol. J Pharm Pharmacol 1972;24:853–7.

    PubMed  Google Scholar 

  13. Gijbels MJM. Phthalides in Umbelliferae. Leiden: State University of Leiden, 1983. Dissertation.

    Google Scholar 

  14. Gijbels MJM, Fischer FC, Scheffer JJC, Baerheim Svendsen A. Phthalides in the roots ofApium graveolens, A. graveolens var.rapaceum, Bifora testiculala andPetroselinum crispum var.tuberosum. Fitoterapia 1985;56:17–23.

    Google Scholar 

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Authors and Affiliations

  1. Medicinal and Aromatic Plants Research Group, National Research Centre, Dokki, Cairo, Egypt

    M. M. Saleh

  2. Laboratory of Pharmacognosy, State University of Groningen, Ant. Deusinglaan 2, 9713, AW Groningen, The Netherlands

    J. H. Zwaving, Th. M. Malingré & R. Bos

Authors
  1. M. M. Saleh
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  2. J. H. Zwaving
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  3. Th. M. Malingré
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  4. R. Bos
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Saleh, M.M., Zwaving, J.H., Malingré, T.M. et al. The essential oil of Apium graveolens var. secalinum and its cercaricidal activity. Pharmaceutisch Weekblad Scientific Edition 7, 277–279 (1985). https://doi.org/10.1007/BF01959202

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  • DOI: https://doi.org/10.1007/BF01959202

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