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Gamma irradiation of Sennae Folium

Microbiological and phytochemical studies

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Abstract

The effect of different doses of gamma irradiation on senna leaves was studied. No changes in sennoside content and composition were observed after irradiation with 25 kGy. It was demonstrated that a minimum dose of 10 kGy was necessary to obtain a product of good microbiological quality. Cold maceration of senna leaves has to be discouraged, because of unavoidable microbial growth. Hot extraction is the method of choice for tea preparation. The rationale of gamma irradiation is discussed.

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Authors and Affiliations

  1. Department of Pharmaceutical Technology and Biopharmaceutics, State University of Groningen, Ant. Deusinglaan 2, 9713, AW Groningen, the Netherlands

    H. Van Doorne & E. H. Bosch

  2. Department of Pharmacognosy, State University of Groningen, Ant. Deusinglaan 2, 9713, AW Groningen, the Netherlands

    J. H. Zwaving & E. T. Elema

Authors
  1. H. Van Doorne
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  2. E. H. Bosch
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  3. J. H. Zwaving
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  4. E. T. Elema
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Van Doorne, H., Bosch, E.H., Zwaving, J.H. et al. Gamma irradiation of Sennae Folium. Pharmaceutisch Weekblad Scientific Edition 10, 217–220 (1988). https://doi.org/10.1007/BF01956874

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  • DOI: https://doi.org/10.1007/BF01956874

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