Abstract
A simple and rapid colorimetric method for the determination of some amino acids containing a sulfur group is described. The studied compounds are cysteine, cystine and methionine. The method is based on the formation of ferroin, from the reaction of the studied drugs with a mixture of iron(III) and 1,10-phenanthroline and measurement of the absorbance at 512 nm. The procedure has been successfully applied to the assay of the pharmaceutical preparations of the studied drugs after thinlayer Chromatographic separation and the results of the studied compounds compare favourably with the official methods.
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El-Brashy, A.M., Al-Ghannam, S.M. Colorimetric determination of some amino acids containing a sulfur group. Pharm World Sci 17, 54–57 (1995). https://doi.org/10.1007/BF01875055
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DOI: https://doi.org/10.1007/BF01875055