Abstract
Using living cells in place of nanoparticles of other materials in an ink matrix, it is conceptually possible to print 3D organs. Using ink jet arrays controlled by CAD software, vascular cells can introduce appropriate vascularization or cylindrical vessels to allow blood flow. The successful integration of these functions into tissue engineering can allow for human organ printing. This chapter describes contemporary innovations in tissue engineering and 3D organ printing.
References
Bausch AR, Kroy K (2006) A bottom-up approach to cell mechanics. Nat Phys 2:231–238
Bello Y, Falabella A, Eaglstein W (2001) Tissue-engineered skin. Current status in wound healing. Am J Clin Dermatol 2(5):305–313
Boland T, Xu T, Damon B, Cui X (2006) Application of inkjet printing to tissue engineering. Biotechnology 1:910–917
Bottcher-Haberzeth S, Biedermann T, Reichmann E (2010) Tissue engineering of skin. Burns 36:450–460
Cui X, Boland T (2009) Human microvasculature fabrication using thermal inkjet printing technology. Biomaterials 30:6221–6227
Cui H, Nowicki M, Fisher JP, Zhang LG (2017) 3D bioprinting of organ regeneration. Adv Healthc Mater 6(1):1601118
Gu Q, Tomaskovic-Crook E, Lozano R, Chen Y, Kapsa RM, Zhou Q, Wallace GE, Crook JM (2016) Stem cell bioprinting: functional 3D neural mini-tissue from gel-based bioink and human neural stem cells. Adv Healthc Mater 5(12):1429–1438
Hoch E, Tovar GE, Borchers K (2014) Bioprinting of artificial blood vessels: current approaches towards a demanding goal. Eur J Cardiothorac Surg 46(5):767–778
Hospodiuk M, Dey M, Sosnovski D, Osbolat IT (2017) The bioink: a comprehensive review on bioprintable materials. Biotechnol Adv. doi:10.1016/j.biotechadv.12.oo6
Jung JW, Lee J-S, Cho D-W (2016) Computer-aided multiple-head 3D printing system for printing of heterogeneous organ/tissue constructs. Sci Report 6:21685
Kang H-W, Lee SJ, Ku IK, Kengla C, Yoo JJ, Atala A (2016) A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Nat Biotechnol 34:312–319
Kasza KE, Rowat AC, Liu J, Angelini TE, Brongwynne CP, Koenderink GH, Weitz DA (2007) The cell as a material. Curr Opin Cell Biol 19:101–107
Langer R (2007) Tissue engineering: perspectives, challenges, and future directions. Tissue Eng 13:1–2
Li J, He L, Zhou C, Zhou Y, Bai Y, Lee FY, Mao JJ (2015) 3D printing for regenerative medicine: from bench to bedside. MRS Bull 40(2):145–154
Ma PX, Elisseeff J (eds) (2005) Scaffolding in tissue engineering. CRC Press, Boca Raton
Melchelo F, Domingos PW, Neves MA, Klein TJ, Maida J, Bartolo PJ, Hatmacher D (2011) Additive manufacturing of tissue and organs. Prog Polym Sci 37(31):1079–1104
Mironov V, Boland T, Trask T, Forgacs G, Markwald RR (2003) Organ printing: computer-aided jet-based 3D tissue engineering. Trends Biotechnol 21:157–161
Mironov V, Visconti RP, Kasyanov V, Forgacs G, Drake CJ, Markwald RP (2009) Organ printing: tissue spheroids as building blocks. Biomaterials 30:2164–2174
Murphy SV, Atala A (2014) 3D bio printing of tissue and organs. Nat Biotechnol 32:773–785
Ozbolat IT (2017) 3D bioprinting: fundamentals, principles and applications. Academic/Elsevier, New York
Radenkovic D, Solak A, Seifalian A (2016) Personalized development of human organs using 3D printing technology. Med Hypotheses 87:30–33
Reiffel AJ, Kafka C, Hernandez KA, Popa S, Perez JL, Zhau S, Pramanik S, Brown BN, Ryu WS, Bonassar LJ, Spector JA (2013) High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities. PLoS One 8(2):e56506
Sun W, Lai P (2002) Recent development on computer-aided tissue engineering – a review. Comput Methods Prog Biomed 67:85–103
Tripathi A, Melo JS (2017) Advances in biomaterials for medical applications, Advanced structural materials, vol 66. Springer, Singapore. Zhang X-F, Huang Y, Guo G, Cui X: Current progress in bioprinting: 227–259
Yanez M, Rincon J, Cortez P, Gänthes N, Boland T (2012) Printable cellular scaffold using self-crosslinking agents. J Imaging Sci Technol 56(4):040506-1–040506-5
Zhang YS, Yue K, Aleman J, Mollezadeh-Moghaddam K, Bakht SM, Yang J, Jia W, Dell’Erba V, Assawes P, Shin SR, Dokmeci MR, Oklu R (2017) 3D bioprinting for tissue and organ fabrication. Ann Biomed Eng 45(1):148–163
Zhu W, Qu X, Ma X, Pater S, Liu J, Wang P, Sun C, Lai E, Gou M, Xu Y, Zhang K, Chen S (2017) Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture. Biomaterials 124:106–115
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this entry
Cite this entry
Murr, L.E. (2017). Bioprinting and Biofabrication of Organs. In: Handbook of Materials Structures, Properties, Processing and Performance. Springer, Cham. https://doi.org/10.1007/978-3-319-01905-5_36-2
Download citation
DOI: https://doi.org/10.1007/978-3-319-01905-5_36-2
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-01905-5
Online ISBN: 978-3-319-01905-5
eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics
Publish with us
Chapter history
-
Latest
Bioprinting and Biofabrication of Organs- Published:
- 06 April 2017
DOI: https://doi.org/10.1007/978-3-319-01905-5_36-2
-
Original
Bioprinting and Biofabrication of Organ- Published:
- 10 June 2014
DOI: https://doi.org/10.1007/978-3-319-01905-5_36-1