Abstract
Macromolecular crystallography is discussed in terms of its impact on medicine, and selected examples of protein structures of medical relevance are provided. The application of crystallography to the study of genetic diseases is covered, as well as the role of crystallography in the development of novel pharmaceuticals. This chapter is also available as HTML from the International Tables Online site hosted by the IUCr.
Keywords
- Dihydrofolate Reductase
- Triosephosphate Isomerase
- Trypanosoma Brucei
- Purine Nucleoside Phosphorylase
- Maple Syrup Urine Disease
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 2006 International Union of Crystallography
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Hol, W.G.J., Verlinde, C.L.M.J. (2006). Macromolecular crystallography and medicine. In: Rossmann, M.G., Arnold, E. (eds) International Tables for Crystallography Volume F: Crystallography of biological macromolecules. International Tables for Crystallography, vol F. Springer, Dordrecht. https://doi.org/10.1107/97809553602060000656
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DOI: https://doi.org/10.1107/97809553602060000656
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-6857-1
Online ISBN: 978-1-4020-5416-7
eBook Packages: Springer Book Archive