Introduction
The organic salts comprising of sterically mismatched ions and also with relatively low melting point (generally below 100 °C) but excellent thermal stability are known as ionic liquids (ILs). In recent times, they are extensively used in different research fields; but historically these ILs are not very new. Although the first published review on room temperature ionic liquid (RTIL) came in the year of 1999 by Thomas Welton, the earliest RTIL, ethylammonium nitrate (EAN, [EtNH3][NO3]), was reported by Paul Walden in 1914. However, in India, Rây and Sen did excellent works and made significant contributions in this particular field since 1911. Besides the RTILs, the ILs having long alkyl hydrophobic chains and inherent amphiphilic characteristics are known as surface-active ionic liquids (SAILs). The structural dissection of the ILs reveals that most of the ILs containing imidazolium or pyrrolidinium head groups and long hydrophobic alkyl chains lead to their aggregation...
References
Ghosh S, Kuchlyan J, Roychowdhury S, Banik D, Kundu N, Roy A, Sarkar N (2014) Unique influence of cholesterol on modifying the aggregation behavior of surfactant assemblies: investigation of photophysical and dynamical properties of 2,2′-bipyridine-3,3′-diol, BP(OH)2 in surfactant micelles, and surfactant/cholesterol forming vesicles. J Phys Chem B 118:9329–9340
Kaler EW, Murthy AK, Rodriguez BE, Zasadzinski JAN (1989) Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants. Science 245:1371–1374
Dutta R, Kundu S, Sarkar N (2018) Ionic liquid-induced aggregate formation and their applications. Biophys Rev 10:861–871
Kuchlyan J, Banik D, Roy A, Kundu N, Sarkar N (2015) Vesicles formation by zwitterionic micelle and poly-l-lysine: solvation and rotational relaxation study. J Phys Chem B 119:8285–8292
Dutta R, Ghosh S, Banerjee P, Kundu S, Sarkar N (2017) Micelle-vesicle-micelle transition in aqueous solution of anionic surfactant and cationic imidazolium surfactants: alteration of the location of different fluorophores. J Colloid Interface Sci 490:762–773
Ghosh S, Ghatak C, Banerjee C, Mandal S, Kuchlyan J, Sarkar N (2013) Spontaneous transition of micelle–vesicle–micelle in a mixture of cationic surfactant and anionic surfactant-like ionic liquid: a pure nonlipid small unilamellar vesicular template used for solvent and rotational relaxation study. Langmuir 29:10066–10076
Mandal S, Kuchlyan J, Banik D, Ghosh S, khorwal V, Sarkar N (2014) Ultrafast FRET to study spontaneous micelle-to-vesicle transitions in an aqueous mixed surface-active ionic-liquid system. ChemPhysChem 15:3544–3553
Pramanik R, Sarkar S, Ghatak C, Rao VG, Sarkar N (2011) Ionic liquid containing microemulsions: probe by conductance, dynamic light scattering, diffusion-ordered spectroscopy NMR measurements, and study of solvent relaxation dynamics. J Phys Chem B 115:2322–2330
Mandal S, Ghosh S, Banerjee C, Kuchlyan J, Banik D, Sarkar N (2013) A novel ionic liquid-in-oil microemulsion composed of biologically acceptable components: an excitation wavelength dependent fluorescence resonance energy transfer study. J Phys Chem B 117:3221–3231
Banerjee C, Roy A, Kundu N, Banik D, Sarkar N (2016) A new strategy to prepare giant vesicles from surface active ionic liquids (SAILs): a study of protein dynamics in a crowded environment using a fluorescence correlation spectroscopic technique. Phys Chem Chem Phys 18:14520–14530
Pyne A, Kuchlyan J, Maiti C, Dhara D, Sarkar N (2017) Cholesterol based surface active ionic liquid that can form microemulsions and spontaneous vesicles. Langmuir 33:5891–5899
Kundu N, Banik D, Roy A, Kuchlyan J, Sarkar N (2015) Modulation of the aggregation properties of sodium deoxycholate in presence of hydrophilic imidazolium based ionic liquid: water dynamics study to probe the structural alteration of the aggregates. Phys Chem Chem Phys 17:25216–25227
Péteilh CT, Coasne B, In M, Brevet D, Devoisselle JM, Vioux A, Viau L (2014) Surfactant behavior of ionic liquids involving a drug: from molecular interactions to self-assembly. Langmuir 30:1229–1238
Pyne A, Kundu S, Banerjee P, Sarkar N (2018) Unveiling the aggregation behavior of doxorubicin hydrochloride in aqueous solution of 1-octyl-3-methylimidazolium chloride and the effect of bile salt on these aggregates: a microscopic study. Langmuir 34:3296–3306
Ghatak C, Rao VG, Mandal S, Ghosh S, Sarkar N (2012) An understanding of the modulation of photophysical properties of curcumin inside a micelle formed by an ionic liquid: a new possibility of tunable drug delivery system. J Phys Chem B 116:3369–3379
Roy A, Dutta R, Sarkar N (2016) Influence of trehalose on the interaction of curcumin with surface active ionic liquid micelle and its vesicular aggregate composed of a non-ionic surfactant sorbitan stearate. Chem Phys Lett 665:14–21
Mahajan S, Sharma R, Mahajan RK (2012) An investigation of drug binding ability of a surface active ionic liquid: micellization, electrochemical, and spectroscopic studies. Langmuir 28:17238–17246
Moniruzzaman M, Kamiya N, Goto M (2010) Ionic liquid based microemulsion with pharmaceutically accepted components: formulation and potential applications. J Colloid Interface Sci 352:136–142
Goindi S, Arora P, Kumar N, Puri A (2014) Development of novel ionic liquid-based microemulsion formulation for dermal delivery of 5-fluorouracil. AAPS PharmSciTech 15:810–821
Nor SBM, Woi PM, Ng SH (2017) Characterisation of ionic liquids nanoemulsion loaded with piroxicam for drug delivery system. J Mol Liq 234:30–39
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this entry
Cite this entry
Pyne, A., Kundu, S., Sarkar, N. (2019). Surfactant Behavior of Ionic Liquids Involving a Drug. In: Zhang, S. (eds) Encyclopedia of Ionic Liquids. Springer, Singapore. https://doi.org/10.1007/978-981-10-6739-6_5-1
Download citation
DOI: https://doi.org/10.1007/978-981-10-6739-6_5-1
Received:
Accepted:
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-6739-6
Online ISBN: 978-981-10-6739-6
eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics