Introduction
One of the main problems in the food industry is the application of nutrients with limited solubility and bioavailability. The requirements of international food regulatory agencies can guide the development of food and its ingredients to comply with the demands of the global food market. In the last decade, FDA started to implement the new plan of the Federal Food, Drug, and Cosmetic Act aimed at assuring the safety of novel food additives before they enter the marketplace. The FDA safety review considers the following criteria: (a) probable additive intake, (b) the cumulative effect of all additive uses, and (c) relevant toxicological data needed to establish the additive safety [1].
One of the possible new formulations that will fulfill consumers’ demand is the use of edible ionic liquids as nutrients and food additives [1, 2]. In the last two decades, ionic liquids (ILs) have been explored and investigated due to their remarkable properties and potential applications...
References
Toledo Hijo AAC, Maximo GJ, Costa MC, Batista EAC, Meirelles AJA (2016) Applications of ionic liquids in the food and bioproducts industries. ACS Sustain Chem Eng 4:5347–5369
Martins PLG, Braga AR, de Rosso VV (2017) Can ionic liquid solvents be applied in the food industry? Trends Food Sci Technol 66:117124
Vastag G, Shaban A, Vraneš M, Tot A, Belić S, Gadžurić S (2018) Influence of the N-3 alkyl chain length on improving inhibition properties of imidazolium-based ionic liquids on copper corrosion. J Mol Liq 264:526–533
Vraneš M, Papović S, Tot A, Zec N, Gadžurić S (2014) Density, excess properties, electrical conductivity and viscosity of 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide + γ-butyrolactone binary mixtures. J Chem Thermodyn 76:161–171
Dimitrijević A, Ignjatović L, Tot A, Vraneš M, Zec N, Gadžurić S, Trtić-Petrović T (2017) Simultaneous extraction of pesticides of different polarity applying aqueous biphasic systems based on ionic liquids. J Mol Liq 243:646–653
Egorova KS, Ananikov VP (2018) Fundamental importance of ionic interactions in the liquid phase: a review of recent studies of ionic liquids in biomedical and pharmaceutical applications. J Mol Liq. https://doi.org/10.1016/j.molliq.2018.09.025
Tot A, Vraneš M, Maksimović I, Putnik-Delić M, Daničić M, Belić S, Gadžurić S (2017) The effect of imidazolium based ionic liquids on wheat and barley germination and growth: influence of length and oxygen functionalization of alkyl side chain. Ecotoxicol Environ Saf 147:401–406
Vraneš M, Tot A, Jovanović-Šanta S, Karaman M, Dožić S, Tešanović K, Kojić V, Gadžurić S (2016) Toxicity reduction of imidazolium-based ionic liquids by the oxygenation of the alkyl substituent. RSC Adv 6:96289–96295
Hou XD, Liu QP, Smith TJ, Li N, Zong MH (2013) Evaluation of toxicity and biodegradability of cholinium amino acids ionic liquids. PLoS One 8:59145–59152
Petkovic M, Ferguson JL, Nimal Gunaratne HQ, Ferreira R, Leitão MC, Seddon KR, Rebelo LPN, Pereira CS (2010) Novel biocompatible cholinium-based ionic liquids—toxicity and biodegradability. Green Chem 12:643–649
Maximo GJ, Santos RJBN, Lopes-Da-Silva JA, Costa MC, Meirelles AJA, Coutinho JAP (2014) Lipidic protic ionic liquid crystals. ACS Sustain Chem Eng 2:672–682
Vraneš M, Tot A, Papović S, Četojević-Simin D, Markov S, Velićanski A, Popsavin M, Gadžurić S (2017) Physicochemical features and toxicity of some vitamin based ionic liquids. J Mol Liq 247:411–424
Zhang S, Ma L, Wen P, Ye X, Dong R, Suna W, Fan M, Yang D, Zhou F, Liu W (2018) The ecotoxicity and tribological properties of choline amino acid ionic liquid lubricants. Tribol Int 121:435–441
Gouveia W, Jorge TF, Martins S, Meireles M, Carolino M, Cruz C, Almeida TV, Araújo MEM (2014) Toxicity of ionic liquids prepared from biomaterials. Chemosphere 104:51–56
Nockemann P, Thijs B, Driesen K, Janssen CR, Van Hecke K, Van Meervelt L, Kossmann S, Kirchner B, Binnemans K (2007) Choline saccharinate and choline acesulfamate: ionic liquids with low toxicities. J Phys Chem B 111:5254–5263
Frade RFM, Matias A, Branco LC, Afonso CAM, Duarte CMM (2007) Effect of ionic liquids on human colon carcinoma HT-29 and CaCo-2 cell lines. Green Chem 9:873–877
De Santis S, Masci G, Casciotta F, Caminiti R, Scarpellini E, Campetella M, Gontrani L (2015) Cholinium-amino acid based ionic liquids: a new method of synthesis and physico-chemical characterization. Phys Chem Chem Phys 17:20687–20698
Gadžurić S, Tot A, Armaković S, Armaković SJ, Panić J, Jović B, Vraneš M (2017) Uncommon structure making/breaking behaviour of cholinium taurate in water. J Chem Thermodyn 107:58–64
Rudan-Tasić D, Klofutar C (2004) Volumetric properties of aqueous solutions of some cyclohexylsulfamates at 25.0 °C. Food Chem 84:351–357
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Vraneš, M., Tot, A. (2019). New Liquid Components in Formulation of Food Supplements. In: Zhang, S. (eds) Encyclopedia of Ionic Liquids. Springer, Singapore. https://doi.org/10.1007/978-981-10-6739-6_17-1
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DOI: https://doi.org/10.1007/978-981-10-6739-6_17-1
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