Synonyms
Ambient ionization; Cold plasma; Dielectric barrier-discharge (DBD) plasma; Direct analysis; Double-bond positions; Instrumentation; Ionization methods; Non-thermal plasma; Nonpolar lipids; Sterols; Postionization; Triacylglycerols
Lipids need to be ionized for their analysis by mass spectrometry (MS) and ion mobility spectrometry (IMS). Various techniques have been used successfully, such as atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), chemical ionization (CI), electron ionization (EI), electrospray ionization (ESI), desorption electrospray ionization (DESI), fast atom bombardment (FAB), and matrix-assisted laser desorption ionization (MALDI) (Li et al. 2014).
However, the ionization of nonpolar lipids such as sterols and triacylglycerols without derivatization is challenging, why alternative options, such as dielectric barrier discharge (DBD) plasmas, are gaining interest in lipid analysis. For example, the sensitivity of a...
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References
Albert A, Engelhard C. Characteristics of low-temperature plasma ionization for ambient mass spectrometry compared to electrospray ionization and atmospheric pressure chemical ionization. Anal Chem. 2012;84(24):10657–64. https://doi.org/10.1021/ac302287x. http://view.ncbi.nlm.nih.gov/pubmed/23134531.
Benassi M, Berisha A, Romão W, Babayev E, Römpp A, Spengler B. Petroleum crude oil analysis using low-temperature plasma mass spectrometry. Rapid Commun Mass Spectrom. 2013;27(7):825–34. https://doi.org/10.1002/rcm.6518.
Brandt S, Ahrends R, Franzke J (2018) New plasma ionisation sources for mass-spectrometric detection of lipids. In: Wenk MR (ed) Encyclopedia of lipidomics, Springer Netherlands, Dordrecht, pp 1–4, https://doi.org/10.1007/978-94-007-7864-1195-1.
Eliasson B, Hirth M, Kogelschatz U. Ozone synthesis from oxygen in dielectric barrier discharges. J Phys D Appl Phys. 1987;20(11):1421. http://stacks.iop.org/0022-3727/20/i=11/a=010.
García-Reyes JF, Mazzoti F, Harper JD, Charipar NA, Oradu S, Ouyang Z, Sindona G, Cooks RG. Direct olive oil analysis by low-temperature plasma (LTP) ambient ionization mass spectrometry. Rapid Commun Mass Spectrom. 2009;23(19):3057–62. https://doi.org/10.1002/rcm.4220.
Lara-Ortega FJ, Beneito-Cambra M, Robles-Molina J, García-Reyes JF, Gilbert-López B, Molina-Díaz A. Direct olive oil analysis by mass spectrometry: a comparison of different ambient ionization methods. Talanta. 2018;180:168–75. https://doi.org/10.1016/j.talanta.2017.12.027. http://www.sciencedirect.com/science/article/pii/S0039914017312304.
Li L, Han J, Wang Z, Liu J, Wei J, Xiong S, Zhao Z. Mass spectrometry methodology in lipid analysis. Int J Mol Sci. 2014;15(6):10492–507. https://doi.org/10.3390/ijms150610492. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100164/.
Martínez-Jarquín S, Winkler R. Low-temperature plasma (LTP) jets for mass spectrometry (MS): ion processes, instrumental set-ups, and application examples. TrAC Trends Anal Chem. 2017;89:133–45. https://doi.org/10.1016/j.trac.2017.01.013. http://linkinghub.elsevier.com/retrieve/pii/S0165993616301492.
Martínez-Jarquín S, Winkler R. Low-temperature plasma ionization. In: Ambient mass spectroscopy techniques in food and the environment. 1st ed. Milton: CRC Press; 2019. p. 105–24.
Martínez-Jarquín S, Moreno-Pedraza A, Guillén-Alonso H, Winkler R. Template for 3d printing a low-temperature plasma probe. Anal Chem. 2016;88(14):6976–80. https://doi.org/10.1021/acs.analchem.6b01019.
Nørgaard AW, Vibenholt A, Benassi M, Clausen PA, Wolkoff P. Study of ozone-initiated limonene reaction products by low temperature plasma ionization mass spectrometry. J Am Soc Mass Spectrom. 2013;24(7):1090–6. https://doi.org/10.1007/s13361-013-0648-3.
Zhang JI, Tao WA, Cooks RG. Facile determination of double bond position in unsaturated fatty acids and esters by low temperature plasma. Anal Chem. 2011;4738–44. https://doi.org/10.1021/ac1030946. http://www.ncbi.nlm.nih.gov/pubmed/21539336.
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Winkler, R. (2019). Low-Temperature Plasma Ionization of Lipids. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_197-1
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DOI: https://doi.org/10.1007/978-94-007-7864-1_197-1
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