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Supercritical Fluid Extraction: Modifier

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Encyclopedia of Lipidomics

Synonyms

Glycerophosphocholines; Glycerophosphoethanolamines; Glycerophospholipids; Liquid Extraction: acidic extraction; Liquid Extraction: Bligh & Dyer; Liquid Extraction: BUME; Liquid Extraction: Single-phase Butanol/Methanol Extraction; Supercritical Fluid chromatography-mass spectrometry of lipids

Expansion of Targeted Hydrophobic Compounds Using a Modifier

As previously described, SC–CO2 is a suitable medium to extract hydrophobic compounds. On the other hand, complex lipids (e.g., phospholipids, PLs, and glycolipids, GLs) have higher polarity than neutral lipids (e.g., TAG), because they have a hydrophilic head groups (i.e., phosphate groups or sugars). Therefore, extraction efficiencies of complex lipids are lower than that of neutral lipids by SFE with SC–CO2. However, the polarity of SC–CO2can be changed considerably by adding a polar organic solvent such as methanol, ethanol, etc., as a modifier. Thus, in recent years, many SFE applications using greener and less toxic...

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References

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Authors and Affiliations

  1. Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, 812-8582, Fukuoka, Japan

    Hiroaki Takeda, Yoshihiro Izumi & Takeshi Bamba

Authors
  1. Hiroaki Takeda
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  2. Yoshihiro Izumi
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  3. Takeshi Bamba
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Corresponding author

Correspondence to Takeshi Bamba .

Editor information

Editors and Affiliations

  1. Yong Loo Lin School of Medicine Centre for Life Sciences, Singapore, Singapore

    Markus R. Wenk

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© 2016 Springer Science+Business Media Dordrecht

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Takeda, H., Izumi, Y., Bamba, T. (2016). Supercritical Fluid Extraction: Modifier. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_101-1

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  • DOI: https://doi.org/10.1007/978-94-007-7864-1_101-1

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  • Publisher Name: Springer, Dordrecht

  • Online ISBN: 978-94-007-7864-1

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