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Spine Bone Texture and the Trabecular Bone Score (TBS)

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Biomarkers in Bone Disease

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Abstract

Trabecular bone score (TBS) is a gray-level texture measure that can be extracted from two-dimensional lumbar spine dual-energy X-ray absorptiometry (DXA) images and provides skeletal information beyond standard bone mineral density (BMD) measurement. This chapter reviews scientific and clinical evidence on the development, validation, and clinical application of lumbar spine TBS. TBS should not be used alone to determine treatment recommendations, but can be used in association with the World Health Organization fracture risk assessment tool (FRAX) to adjust FRAX probability of fracture in postmenopausal women and older men and additionally guide decisions regarding treatment initiation.

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Authors and Affiliations

  1. Department of Medicine, University of Manitoba, 409 Tache Avenue, Winnipeg, MB, R2H 2A6, Canada

    William D. Leslie

  2. Department of Medicine, Divisions of Geriatrics and Endocrinology, University of Wisconsin, 2870 University Avenue, Suite 100, Madison, WI, 53705, USA

    Neil Binkley

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  1. William D. Leslie
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Correspondence to William D. Leslie .

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Editors and Affiliations

  1. Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, United Kingdom

    Vinood B. Patel

  2. Department of Nutrition and Dietetics, Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom

    Victor R. Preedy

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Leslie, W.D., Binkley, N. (2017). Spine Bone Texture and the Trabecular Bone Score (TBS). In: Patel, V., Preedy, V. (eds) Biomarkers in Bone Disease. Biomarkers in Disease: Methods, Discoveries and Applications. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7693-7_33

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