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The Contribution of Reg Family Proteins to Cell Growth and Survival in Pancreatic Islets

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Islets of Langerhans

Abstract

In 2008, we have reviewed Reg family proteins which have been found and characterized in several systems including cell growth and regeneration in the pancreas. Since then the research scope has expanded significantly to the (patho-)physiology of the liver, intestine, immunity, and cancer. More importantly, in communicating our research findings, we feel the need of further classification in the family of seven independent genes and among key species. A more uniformed terminology should help us to understand their isoform-specific functions and/or mode of activation.

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Abbreviations

HIP:

Gene expressed in hepatocellular carcinoma-intestine-pancreas

PAP:

Pancreatitis-associated protein

PSP:

Pancreatic stone protein

PTP:

Pancreatic thread protein

RELP:

Regenerating protein-like protein

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Acknowledgments

Our research activity was supported by the Canadian Diabetes Association (OG-3-11-3469-JL) and the China Scholarship Council (201208370055).

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  1. Fraser Laboratories for Diabetes Research, Department of Medicine, McGill University Health Centre, 687 Pine Avenue West, Montreal, QC, Canada

    Qing Li, Xiaoquan Xiong & Jun-Li Liu

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  1. Qing Li
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  2. Xiaoquan Xiong
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  3. Jun-Li Liu
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Correspondence to Jun-Li Liu .

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  1. Department of Clinical Sciences and Education, Sodersjukhuset, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

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Li, Q., Xiong, X., Liu, JL. (2015). The Contribution of Reg Family Proteins to Cell Growth and Survival in Pancreatic Islets. In: Islam, M. (eds) Islets of Langerhans. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6686-0_47

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