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Immunosensors: Using Antibodies to Develop Biosensors for Detecting Pathogens and Their Toxins

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Biological Toxins and Bioterrorism

Part of the book series: Toxinology ((TOXI))

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Abstract

Fast, reliable, and low-cost methods for the screening of pathogens are paramount in areas such as environment, the food industry, healthcare, and defense. The word pathogen defines any disease-producing agent.

With the constant progress of scientific knowledge, a fast diversification of the detection techniques is occurring, brought about by the appearance of imaginative new concepts within the scientific community. Biosensors are a perfect example of the combination of multidisciplinary knowledge. They encompass many fundamental, technological, and scientific advances in biology, chemistry, and physics.

This chapter includes an overview of different types of antibodies and labels used as recognition elements for the elaboration of immunosensors. The most common ways to immobilize Ab on a transducer surface will be described and a description of some of the most popular transducing techniques will be given.

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Author information

Authors and Affiliations

  1. Plant Functional Biology and Climate Change Cluster (C3), University of Technology, Sydney, NSW, Australia

    Olivier Laczka

Authors
  1. Olivier Laczka
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Correspondence to Olivier Laczka .

Editor information

Editors and Affiliations

  1. Venom and Toxin Research Programme, Department of Anatomy, Yong Loo Lin School of Medicine National University of Singapore, Singapore, Singapore

    P. Gopalakrishnakone

  2. Medical Toxicology Research Centre Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Mahdi Balali-Mood

  3. Data and Technology Innovation, Australian Institute of Marine Science, Townsville, QLD, Australia

    Lyndon Llewellyn

  4. Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA, USA

    Bal Ram Singh

  5. Prime Bio, Inc., Dartmouth, MA, USA

    Bal Ram Singh

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Laczka, O. (2015). Immunosensors: Using Antibodies to Develop Biosensors for Detecting Pathogens and Their Toxins. In: Gopalakrishnakone, P., Balali-Mood, M., Llewellyn, L., Singh, B.R. (eds) Biological Toxins and Bioterrorism. Toxinology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5869-8_16

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