Skip to main content

Beluga Whales and Ecotoxicity

  • Reference work entry

Synonyms

Beluga ecotoxicology

Glossary

Aromatic (Syn: aryl):

Compounds made of stable rings of atoms. Ring stability is conferred by the atoms composing the rings sharing electrons.

Coal Tar Pitch Volatile:

Fused polycyclic hydrocarbons which are volatilized when coal, petroleum (excluding asphalt), wood, and other organic compounds are distilled.

CYP Enzymes:

Enzymes involved in the degradation of foreign molecules but also in the synthesis and degradation of normal hormones such as steroids.

DDT:

Insecticide used since World War II. Still permitted under the Stockholm Convention but banned in Canada and the USA since early 1970s. Employed to reduce malaria incidence but at the same time accumulated in the tissues of top predators, causing the decline of many species of birds of prey.

Immunosuppressive:

That impairs immune functions.

Lipophilic:

“Fat loving.” Compounds which are highly soluble in fat (and poorly soluble in water).

Lymphocytes:

White blood cells which play a very...

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   649.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Aguilar A, Borrell A (1994) Abnormally high polychlorinated biphenyl levels in striped dolphins (stenella coeruleoalba) affected by the 1990–1992 Mediterranean epizootic. Sci Total Environ 154:237–247

    Article  CAS  Google Scholar 

  • Alberg A, Brock MV, Samet JM (2005) Epidemiology of lung cancer: looking to the future. J Clin Oncol 23:3175–3185

    Article  Google Scholar 

  • Armstrong B, Tremblay C, Baris D et al (1994) Lung cancer mortality and polynuclear aromatic hydrocarbons: a case-cohort study of aluminum production workers in arvida, Quebec, Canada. Am J Epidemiol 139:250–262

    CAS  Google Scholar 

  • Beach DG, Quilliam MA, Hellou J (2009) Analysis of pyrene metabolites in marine snails by liquid chromatography using fluorescence and mass spectrometry detection. J Chromatogr B 877:2142–2152

    Article  CAS  Google Scholar 

  • Blondin O, Viau C (1992) Benzo (a) pyrene-blood protein adducts in wild woodchucks used as biological sentinels of environmental polycyclic aromatic hydrocarbons contamination. Arch Environ Contam Toxicol 23:310–315

    Article  CAS  Google Scholar 

  • Bouchard M, Viau C (1999) Urinary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons: biological monitoring strategies and methodology for determining biological exposure indices for various work environments. Biomarkers 4:159–187

    Article  CAS  Google Scholar 

  • Bouchard M, Normandin L, Gagnon F et al (2009) Repeated measures of validated and novel biomarkers of exposure to polycyclic aromatic hydrocarbons in individuals living near an aluminum plant in Quebec, Canada. J Toxicol Environ Health A 72:1534–1549

    Article  CAS  Google Scholar 

  • Bredhult C, Bäcklin B, Bignert A et al (2008) Study of the relation between the incidence of uterine leiomyomas and the concentrations of PCB and DDT in Baltic gray seals. Reprod Toxicol 25:247–255

    Article  CAS  Google Scholar 

  • Brouwer A, Reijnders P, Koeman J (1989) Polychlorinated biphenyl (PCB)-contaminated fish induces vitamin a and thyroid hormone deficiency in the common seal (phoca vitulina). Aquat Toxicol 15:99–105

    Article  CAS  Google Scholar 

  • Brunström B (1992) Induction of cytochrome P-450-dependent enzyme activities in female mink (mustela vison) and their kits by technical PCB preparations and fractions thereof. Ambio 21:585–587

    Google Scholar 

  • Caron L, Sergeant D (1988) Yearly variation in the frequency of passage of beluga whales (Delphinapterus leucas) at the mouth of the Saguenay River, Quebec, over the past decade. Naturaliste canadien. (Revue d’Ecologie et de Systématique) 115:111–116

    Google Scholar 

  • Chevrier J, Eskenazi B, Holland N et al (2008) Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy. Am J Epidemiol 168:298–310

    Article  Google Scholar 

  • Cossa D, Picard-Bérubé M, Gouygou JP (1983) Polynuclear aromatic hydrocarbons in mussels from the estuary and northwestern gulf of St. Lawrence, Canada. Bull Environ Contam Toxicol 31:41–47

    Article  CAS  Google Scholar 

  • Cossa D (1990) Chemical contaminants in the St. Lawrence estuary and Saguenay fjord. In: El-Sabh MI, Silverberg N (eds) Coastal and estuarine studies 39. Oceanography of a large-scale estuarine system, the St Lawrence. Springer, New York

    Google Scholar 

  • Crofton KM, Zoeller RT (2005) Mode of action: neurotoxicity induced by thyroid hormone disruption during development – hearing loss resulting from exposure to PHAHs. Crit Rev Toxicol 35:757–769

    Article  CAS  Google Scholar 

  • De Guise S, Martineau D, Béland P et al (1998) Effects of in vitro exposure of beluga whale leukocytes to selected organochlorines. J Toxicol Environ Health A 55:479–493

    Article  Google Scholar 

  • Fishbein L (1974) Toxicity of chlorinated biphenyls. Annu Rev Pharmacol 14:139–156

    Article  CAS  Google Scholar 

  • Fisk AT, De Wit CA, Wayland M et al (2005) An assessment of the toxicological significance of anthropogenic contaminants in Canadian arctic wildlife. Sci Total Environ 351–352:57–93

    Article  CAS  Google Scholar 

  • Gauthier JM, Pelletier É, Brochu C et al (1998) Environmental contaminants in tissues of a neonate St Lawrence beluga whale (delphinapterus leucas). Mar Pollut Bull 36:102–108

    Article  CAS  Google Scholar 

  • Gibbs G, Armstrong B, Sevigny M (2007) Mortality and cancer experience of Quebec aluminum reduction plant workers, part 2: mortality of three cohorts hired on or before January 1, 1951. J Occup Environ Med 49:1105–1123

    Article  CAS  Google Scholar 

  • Gilbert N, Viau C (1997) Biological monitoring of environmental exposure to PAHs in the vicinity of a söderberg aluminium reduction plant. Occup Environ Med 54:619–621

    Article  CAS  Google Scholar 

  • Gosselin JF, Hammill M, Lesage V (2007) Comparison of photographic and visual abundance indices of belugas in the St. Lawrence Estuary in 2003 and 2005. C. S. A. S. C. S. A. Secretariat. Maurice Lamontagne Institute, Mont-Joli (Quebec, Canada)

    Google Scholar 

  • Hall A, Law R, Wells D et al (1992) Organochlorine levels in common seals (phoca vitulina) which were victims and survivors of the 1988 phocine distemper epizootic. Sci Total Environ 115:145–162

    Article  CAS  Google Scholar 

  • Hall A, Hugunin K, Deaville R et al (2006) The risk of infection from polychlorinated biphenyl exposure in the harbor porpoise (phocoena phocoena): a case–control approach. Environ Health Perspect 114:704–711

    Article  CAS  Google Scholar 

  • Hallgren S, Sinjari T, Håkansson H et al (2001) Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin a levels in rats and mice. Arch Toxicol 75:200–208

    Article  CAS  Google Scholar 

  • Hellou J, Hodson P, Upshall C (1995) Contaminants in muscle of plaice and halibut collected from the St Lawrence estuary and Northwest Atlantic. Chem Ecol 11:11–24

    Article  CAS  Google Scholar 

  • Hickie B, Kingsley M, Hodson P et al (2000) A modelling-based perspective on the past, present, and future polychlorinated biphenyl contamination of the St. Lawrence beluga whale (delphinapterus leucas) population. Can J Fish Aquat Sci 57:101–112

    CAS  Google Scholar 

  • Hobbs K, Muir D, Michaud R et al (2003) PCBs and organochlorine pesticides in blubber biopsies from free-ranging St. Lawrence river estuary beluga whales (delphinapterus leucas), 1994–1998. Environ Pollut 122:291–302

    Article  CAS  Google Scholar 

  • IARC (2010) IARC monographs on the evaluation of carcinogenic risks to humans, some Non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures. World Health Organization. International Agency for Research on Cancer, Lyon, France, 92

    Google Scholar 

  • Jepson P, Bennett P, Deaville R et al (2005) Relationships between polychlorinated biphenyls and health status in harbor porpoises (phocoena phocoena) stranded in the United Kingdom. Environ Toxicol Chem 24:238–248

    Article  CAS  Google Scholar 

  • Jongeneelen FJ, Anzion RBM, Leijdekkers CM et al (1985) 1-Hydroxypyrene in human urine after exposure to coal tar and a coal tar derived product. Int Arch Occup Environ Health 57:47–55

    Article  CAS  Google Scholar 

  • Jongeneelen F (2001) Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons. Ann Occup Hyg 45:3–13

    CAS  Google Scholar 

  • Jugan M, Levi Y, Blondeau J (2010) Endocrine disruptors and thyroid hormone physiology. Biochem Pharmacol 79:939–947

    Article  CAS  Google Scholar 

  • Kannan K, Blankenship A, Jones P et al (2000) Toxicity reference values for the toxic effects of polychlorinated biphenyls to aquatic mammals. Hum Ecol Risk Assess 6:181–201

    Article  CAS  Google Scholar 

  • Kannan K, Kajiwara N, Le Boeuf BJ et al (2004) Organochlorine pesticides and polychlorinated biphenyls in California sea lions. Environ Pollut 131:425–434

    Article  CAS  Google Scholar 

  • Kimbrough RD, Barnes MM, Greig JB (1973) The toxicity of polychlorinated polycyclic compounds and related chemicals. Crit Rev Toxicol 2:445–498

    Article  Google Scholar 

  • Lapointe R (2008) Les hydrocarbures aromatiques polycycliques, de la recherche à la prévention. Colloque international francophone, Montréal,http://www.mapageweb.umontreal.ca/ciauc/Colloque_HAP/Resume/lapointe.htm

  • Lebeuf M, Noël M, Trottier S et al (2007) Temporal trends (1987–2002) of persistent, bioaccumulative and toxic (PBT) chemicals in beluga whales (delphinapterus leucas) from the St. Lawrence estuary, Canada. Sci Total Environ 383:216–231

    Article  CAS  Google Scholar 

  • Lebeuf M (2009) La contamination du béluga de l’estuaire du saint-Laurent par les polluants organiques persistants en revue. Rev Sci Eau 22:199–233

    Google Scholar 

  • Lesage V, Hammill MO, Kovacs KM (2001) Marine mammals and the community structure of the estuary and gulf of St Lawrence, Canada: evidence from stable isotope analysis. Mar Ecol Prog Ser 210:203–221

    Article  CAS  Google Scholar 

  • Levengood JM, Beasley VR (2012) Ecotoxicology: bridging wildlife, humans and ecosystems. In: Aguirre AA, Ostfeld RS, Daszak P (eds) New directions in conservation Medicine, Oxford University Press, New York

    Google Scholar 

  • Levin M, Morsey B, Mori C et al (2004) Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure. J Toxicol Environ Health A 67:1517–1535

    Article  CAS  Google Scholar 

  • Lyon R, (2004) http://www.minesandcommunities.org/article.php?a=72 Accessed 7 Dec 2010

  • Mariussen E, Fonnum F (2006) Neurochemical targets and behavioral effects of organohalogen compounds: an update. Crit Rev Toxicol 36:253–289

    Article  CAS  Google Scholar 

  • Martel L, Gagnon M, Massé R et al (1986) Polycyclic aromatic hydrocarbons in sediments from the Saguenay fjord, Canada. Bull Environ Contam Toxicol 37:133–140

    Article  CAS  Google Scholar 

  • Martel L, Gagnon M, Massé R et al (1987) The spatio-temporal variations and fluxes of polycyclic aromatic hydrocarbons in the sediments of the Saguenay fjord, Québec, Canada. Water Res 21:699–707

    Article  CAS  Google Scholar 

  • Martineau D, Béland P, Desjardins C et al (1987) Levels of organochlorine chemicals in tissues of beluga whales (delphinapterus leucas) from the St. Lawrence estuary, Quebec, Canada. Arch Environ Con Tox 16:137–147

    Article  CAS  Google Scholar 

  • Martineau D, Lagace A, Beland P et al (1988) Pathology of stranded beluga whales (delphinapterus leucas) from the St. Lawrence eestuary, Quebec, Canada. J Comp Pathol 98:287–310

    Article  CAS  Google Scholar 

  • Martineau D, Lemberger K, Dallaire A et al (2002a) Cancer in wildlife, a case study: beluga from the St. Lawrence estuary, Québec, Canada. Environ Health Perspect 110:285–292

    Article  Google Scholar 

  • Martineau D, Lemberger K, Dallaire A et al (2002b) St. Lawrence beluga whales, the river sweepers? Env Health Perspect 110:A562–A563

    Article  Google Scholar 

  • Massé R, Martineau D, Tremblay L et al (1986) Concentrations and chromatographic profile of DDT metabolites and polychlorobiphenyl (PCB) residues in stranded beluga whales (delphinapterus leucas) from the St. Lawrence estuary, Canada. Arch Environ Con Tox 15:567–579

    Article  Google Scholar 

  • Mcaloose D, Newton A (2009) Wildlife cancer: a conservation perspective. Nat Rev Cancer 9:517–526

    Article  CAS  Google Scholar 

  • Mckinney M, Arukwe A, De Guise S et al (2004) Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (delphinapterus leucas) from the St Lawrence river estuary and the Canadian arctic. Aquat Toxicol 69:35–49

    Article  CAS  Google Scholar 

  • Mckinney M, De Guise S, Martineau D et al (2006) Organohalogen contaminants and metabolites in beluga whale (delphinapterus leucas) liver from two Canadian populations. Environ Toxicol Chem 25:1246–1257

    Article  CAS  Google Scholar 

  • Meador J, Stein J, Reichert W et al (1995) Bioaccumulation of polycyclic aromatic hydrocarbons by marine organisms. Rev Environ Contam Toxicol 143:79–165

    Article  CAS  Google Scholar 

  • Michaud R (1993) Distribution estivale du béluga du Saint-Laurent; synthèse 1986 à 1992. Direction de la gestion des pêches et de l’habitat. Division de la gestion de l’habitat du poisson. Ministère des Pêches et des Océans. Québec (Québec). Rapport technique canadien des sciences halieutiques et aquatiques 1906

    Google Scholar 

  • Mikaelian I, De Lafontaine Y, Ménard C et al (1998) Neoplastic and nonneoplastic hepatic changes in lake whitefish (coregonus clupeaformis) from the St. Lawrence river, Quebec, Canada. Environ Health Perspect 106:179–183

    Article  CAS  Google Scholar 

  • Mikaelian I, De Lafontaine Y, Harshbarger J et al (2002) Health of lake whitefish (coregonus clupeaformis) with elevated tissue levels of environmental contaminants. Environ Toxicol Chem 21:532–541

    CAS  Google Scholar 

  • Mikaelian I, Labelle P, Kopal M et al (2003) Adenomatous hyperplasia of the thyroid gland in beluga whales (delphinapterus leucas) from the St. Lawrence estuary and Hudson Bay, Quebec, Canada. Vet Pathol 40:698–703

    Article  CAS  Google Scholar 

  • Mori C, Morsey B, Levin M et al (2008) Effects of organochlorines, individually and in mixtures, on B-cell proliferation in marine mammals and mice. J Toxicol Environ Health A 71:266–275

    Article  CAS  Google Scholar 

  • Muir D, Ford C, Stewart R et al (1990) Organochlorine contaminants in belugas, delphinapterus leucas, from Canadian waters. Can B Fish Aquat Sci 224:165–190

    Google Scholar 

  • Muir D, Ford C, Rosenberg B et al (1996) Persistent organochlorines in beluga whales (delphinapterus leucas) from the St Lawrence river estuary-I. Concentrations and patterns of specific PCBs, chlorinated pesticides and polychlorinated dibenzo-p-dioxins and dibenzofurans. Environ Pollut 93:219–234

    Article  CAS  Google Scholar 

  • Munson L, Calzada N, Kennedy S et al (1998) Luteinized ovarian cysts in Mediterranean striped dolphins. J Wildl Dis 34:656–660

    CAS  Google Scholar 

  • Nebert D, Dalton T, Okey A et al (2004) Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 279:23847–23850

    Article  CAS  Google Scholar 

  • Pelletier É, Desbiens I, Sargian P et al (2009) Présence des hydrocarbures aromatiques polycycliques (HAP) dans les compartiments biotiques et abiotiques de la rivière et du fjord du Saguenay. Rev Sci Eau 22:235–251

    CAS  Google Scholar 

  • Perera F, Hemminki K, Gryzbowska E et al (1992) Molecular and genetic damage in humans from environmental pollution in Poland. Nature 360:256–258

    Article  CAS  Google Scholar 

  • Perera F, Weinstein I (2000) Molecular epidemiology: recent advances and future directions. Carcinogenesis 21:517–524

    Article  CAS  Google Scholar 

  • Pham T, Lum K, Lemieux C (1993) Sources of PAHs in the St Lawrence river (Canada) and their relative importance. Chemosphere 27:1137–1149

    Article  Google Scholar 

  • Picard-Bérubé M, Cossa D, Piuze J (1983) (Benzo 3,4 pyrene content in mytilus edulis of the estuary and gulf of St. Lawrence) teneurs en benzo 3.4 Pyrene chez mytilus edulis L. de l’estuaire et du golfe du saint-Laurent. Mar Environ Res 10:63–71

    Article  Google Scholar 

  • Reijnders P (1986) Reproductive failure in common seals feeding on fish from polluted coastal waters. Nature 324:456–457

    Article  CAS  Google Scholar 

  • Rogan WJ, Chen A (2005) Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT). Lancet 366:763–773

    Article  CAS  Google Scholar 

  • Ross P, De Swart R, Addison R et al (1996) Contaminant-induced immunotoxicity in harbour seals: wildlife at risk? Toxicol 112:157–169

    Article  CAS  Google Scholar 

  • Ross P, Ellis G, Ikonomou M et al (2000a) High PCB concentrations in free-ranging pacific killer whales, orcinus orca: effects of age, sex and dietary preference. Mar Pollut Bull 40:504–515

    Article  CAS  Google Scholar 

  • Ross P, Vos J, Birnbaum L et al (2000b) PCBs are a health risk for humans and wildlife. Science 289:1878–1879

    Article  CAS  Google Scholar 

  • Ruzzin J, Petersen R, Meugnier E et al (2010) Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 118:465–471

    Article  CAS  Google Scholar 

  • Safe SH (1994) Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit Rev Toxicol 24:87–149

    Article  CAS  Google Scholar 

  • Saint-Amour D, Roy MS, Bastien C et al (2006) Alterations of visual evoked potentials in preschool Inuit children exposed to methylmercury and polychlorinated biphenyls from a marine diet. Neurotoxicol 27:567–578

    Article  CAS  Google Scholar 

  • Schwacke LH, Voit EO, Hansen LJ et al (2002) Probabilistic risk assessment of reproductive effects of polychlorinated biphenyls on bottlenose dolphins (tursiops truncatus) from the southeast United States Coast. Environ Toxicol Chem 21:2752–2764

    CAS  Google Scholar 

  • Sergeant DE (1980) Levels of mercury and organochlorine residues in tissues of sea mammals from the St. Lawrence estuary International Council for the Exploration of the Sea. Marine Environmental Quality Committee. Ref. Marine Mammals Committee 10

    Google Scholar 

  • Shugart L, Theodorakis C (1994) Environmental genotoxicity: probing the underlying mechanisms. Env Health Perspect 102(Suppl 12):13–17

    Article  Google Scholar 

  • Shugart L, Theodorakis C (1998) New trends in biological monitoring: application of biomarkers to genetic ecotoxicology. Biotherapy 11:119–127

    Article  CAS  Google Scholar 

  • Simon T, Britt JK, James RC (2007) Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures. Regul Toxicol Pharmacol 48:148–170

    Article  CAS  Google Scholar 

  • Smith J, Levy E (1990) Geochronology for polycyclic aromatic hydrocarbon contamination in sediments of the Saguenay fjord. Environ Sci Technol 24:874–879

    Article  CAS  Google Scholar 

  • Sonne C, Wolkers H, Leifsson P et al (2009) Chronic dietary exposure to environmental organochlorine contaminants induces thyroid gland lesions in arctic foxes (vulpes lagopus). Environ Res 109:702–711

    Article  CAS  Google Scholar 

  • Spinelli JJ, Demers PA, Le ND et al (2006) Cancer risk in aluminum reduction plant workers (Canada). Cancer Causes Control 17:939–948

    Article  Google Scholar 

  • Steinberg R, Walker DM, Juenger TE et al (2008) Effects of perinatal polychlorinated biphenyls on adult female Rat reproduction: development, reproductive physiology, and second generational effects. Biol Reprod 78:1091–1101

    Article  CAS  Google Scholar 

  • Tairova ZM, Giessing AMB, Hansen R et al (2009) 1-Hydroxypyrene as a biomarker of PAH exposure in the marine polychaete nereis diversicolor. Mar Environ Res 67:38–46

    Article  CAS  Google Scholar 

  • Tanabe S (1988) PCB problems in the future: foresight from current knowledge. Environ Pollut 50:5–28

    Article  CAS  Google Scholar 

  • Tanabe S (1989) A need for reevaluation of PCB toxicity. Mar Pollut Bull 20:247–248

    Article  Google Scholar 

  • Thériault G, Cordier S, Tremblay C et al (1984) Bladder cancer in the aluminium industry. Lancet 323:947–950

    Article  Google Scholar 

  • Turusov V et al (2002) Dichlorodiphenyltrichloroethane (DDT): ubiquity, persistence and risks. Env Health Perspect 110:125–128

    Article  CAS  Google Scholar 

  • Vineis P, Perera F (2007) Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old. Cancer Epidemiol Biomark Prev 16:1954–1965

    Article  CAS  Google Scholar 

  • Vladykov, V (1946) Études sur les mammifères aquatiques. IV. Nourriture du marsouin blanc ou béluga (Delphinapterus leucas) du fleuve Saint-Laurent, Québec. Département des Pêcheries. Québec. No 17. 132 p

    Google Scholar 

  • Weinberg RA (2007) The nature of cancer. In: The biology of cancer. Garland Science, Taylor & Francis Group, New York, pp 25–56

    Google Scholar 

  • Wells RS, Tornero V, Borrell A et al (2005) Integrating life-history and reproductive success data to examine potential relationships with organochlorine compounds for bottlenose dolphins (tursiops truncatus) in Sarasota Bay, Florida. Sci Total Environ 349:106–119

    Article  CAS  Google Scholar 

  • White P, Blaise C, Rasmussen J (1997) Detection of genotoxic substances in bivalve molluscs from the Saguenay fjord (Canada), using the SOS chromotest. Mutat Res 392:277–300

    Article  CAS  Google Scholar 

  • White PA, Rasmussen JB, Blaise C (1998) Genotoxic substances in the St. Lawrence system I: industrial genotoxins sorbed to particulate matter in the St. Lawrence, St. Maurice, and Saguenay rivers, Canada. Environ Toxicol Chem 17:286–303

    CAS  Google Scholar 

  • Yang JM, Salmon AG, Marty MA (2010) Development of TEFs for PCB congeners by using an alternative biomarker – thyroid hormone levels. Regul Toxicol Pharmacol 56:225–236

    Article  CAS  Google Scholar 

Download references

Acknowledgments

I am deeply grateful to Dr Stephane Lair to have shared his data and for his invaluable support in this work. I am very thankful to colleagues Drs. Sylvain DeGuise, Igor Mikaelian, and André Dallaire for their tremendous support and contributions. Many thanks to Pierre Béland (INSEL), Robert Michaud (GREMM), Lena Measures, and Véronique Lesage (DFO) for discussions and documentation. Many thanks also to all the veterinary students who helped throughout these years in the postmortem examinations. I thank François Boudreault and Nathalie Gratton of Environment Canada for assistance with figures. Various organizations have contributed to the funding of this work over the last 30 years: Fisheries and Oceans Canada, World Wildlife Funds, Park Canada, and others.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Martineau .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media Dordrecht

About this entry

Cite this entry

Martineau, D. (2013). Beluga Whales and Ecotoxicity. In: Férard, JF., Blaise, C. (eds) Encyclopedia of Aquatic Ecotoxicology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5704-2_15

Download citation

Publish with us

Policies and ethics