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The Chemistry of Marine Bacteria

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Handbook of Marine Natural Products

Abstract

The world’s oceans harbor extensive levels of bacterial diversity. Although much of this diversity remains uncharacterized, cultured representatives from a broad range of taxonomic groups are proving to be an important source of novel secondary metabolites. These metabolites include new carbon skeletons as well as compounds with a high degree of halogenation, a relatively common feature of marine-derived secondary metabolites. The bacteria being cultured from marine sources include new taxa, which are proving to be a particularly important source of new chemical entities. This chapter will provide the reader with a brief, though not comprehensive history of the secondary metabolites that have been isolated from marine bacteria. The focus is on the taxonomic distribution of the producing strains and interesting structural features and biological activities of the compounds that are being discovered from marine bacteria.

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Acknowledgments

The authors thank the National Institutes of Health (Grant # RO1 GM85770 to PRJ), and in particular the National Cancer Institute (Grant # R37 CA044848 to WF), for their support in developing the field of marine microbial natural products chemistry.

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Authors and Affiliations

  1. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, CA, 92093-0204, USA

    Brian T. Murphy, Paul R. Jensen & William Fenical

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  1. Brian T. Murphy
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  2. Paul R. Jensen
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  3. William Fenical
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Corresponding author

Correspondence to Brian T. Murphy .

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Editors and Affiliations

  1. FacoltĂ  di Farmacia, Dipto. Chimica delle Sostanze Naturali, UniversitĂ  di Napoli, Via Domenico Montesano 49, Napoli, 80131, Italy

    Ernesto Fattorusso

  2. Scripps Inst. Oceanography, University of California, San Diego, Gilman Drive 9500, La Jolla, 92093-0213, California, USA

    William H. Gerwick

  3. FacoltĂ  di Farmacia, Dipto. Chimica delle Sostanze Naturali, UniversitĂ  di Napoli, Via Domenico Montesano 49, Napoli, 80131, Italy

    Orazio Taglialatela-Scafati

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Murphy, B.T., Jensen, P.R., Fenical, W. (2012). The Chemistry of Marine Bacteria. In: Fattorusso, E., Gerwick, W., Taglialatela-Scafati, O. (eds) Handbook of Marine Natural Products. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3834-0_3

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