Skip to main content

Khat Addiction

  • Reference work entry
  • First Online:
Textbook of Addiction Treatment: International Perspectives

Abstract

Khat refers to the young and tender leaves and shoots of the khat tree (Catha edulis). It is an evergreen tree that can be found in the Abyssinian highlands, the Horn of Africa, Eastern and Southern Africa, the Arab peninsula, and Afghanistan. The alkaloid cathinone (S-(-)-a-aminopropiophenone) is considered to be the main psychoactive compound. The leaves and tender stems are usually chewed and kept in a tight wad in the cheek pocket. Within about 15–30 min, the user experiences physiological excitability, euphoria, talkativeness, and flow of ideas. Today, cathinone is listed in Schedule I and cathine in Schedule III of the international Convention on Psychotropic Substances of 1971, but the khat leaves are not internationally controlled. A problem with diagnosis of khat addiction is that established dependence criteria are not easily applicable as is the case for other traditional substances. More research information is needed about the prevalence of a khat dependence, its consequences, and its treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 339.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • al’Absi M, Grabowski J (2012) Concurrent use of tobacco and khat: added burden on chronic disease epidemic. Addiction 107(2):451–452

    Article  PubMed  Google Scholar 

  • Alemseged F, Haileamlak A, Tegegn A, Tessema F, Woldemichael K, Asefa M, Mamo Y, Tamiru S, Abebe G (2012) Risk factors for chronic non-communicable diseases at gilgel gibe field research center, southwest Ethiopia: population based study. Ethiop J Health Sci 22(S):19–28

    PubMed Central  PubMed  Google Scholar 

  • Al-Habori M (2005) The potential adverse effects of habitual use of Catha edulis (khat). Expert Opin Drug Saf 4(6):1145–1154

    Article  PubMed  Google Scholar 

  • Al-Motarreb A, Al-Habori M, Broadley KJ (2010) Khat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future research. J Ethnopharmacol 132:540–548

    Article  CAS  PubMed  Google Scholar 

  • Anderson D, Beckerleg S, Hailu D, Klein A (2007) The Khat controversy: stimulating the debate on drugs. Berg, Oxford

    Google Scholar 

  • Awas M, Kebede D, Alem A (1999) Major mental disorders in Butajira, southern Ethiopia. Acta Psychiatr Scand Suppl 397:56–64

    Article  CAS  PubMed  Google Scholar 

  • Belew M, Kebede D, Kassaye M, Enquoselassie F (2000) The magnitude of khat use and its association with health, nutrition and socio-economic status. Ethiop Med J 38(1):11–26

    CAS  PubMed  Google Scholar 

  • Bhui K, Warfa N (2010) Trauma, khat and common psychotic symptoms among Somali immigrants: a quantitative study. J Ethnopharmacol 132:549–553

    Article  PubMed  Google Scholar 

  • Bhui K, Abdi A, Abdi M, Pereira S, Dualeh M, Robertson D, Sathyamoorthy G, Ismail H (2003) Traumatic events, migration characteristics and psychiatric symptoms among Somali refugees–preliminary communication. Soc Psychiatry Psychiatr Epidemiol 38(1):35–43

    Article  PubMed  Google Scholar 

  • Bimerew MS, Sonn FCT, Korlenbout WP (2007) Substance abuse and the risk of readmission of people with schizophrenia at Amanuel Psychiatric Hospital, Ethiopia. Curationis 30(2):74–81

    Article  CAS  PubMed  Google Scholar 

  • Colzato LS, Ruiz M, Van den Wildenberg WP, Bajo M, Hommel B (2010) Long-term effects of chronic khat use: impaired inhibitory control. Front Psychol 1:129

    Google Scholar 

  • Colzato LS, Ruiz MJ, van den Wildenberg WP, Hommel B (2011) Khat use is associated with impaired working memory and cognitive flexibility. PLoS One 6(6):e20602

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Colzato LS, Ruiz MJ, van den Wildenberg WP, Hommel B (2012) Khat use is associated with increased response conflict in humans. Hum Psychopharm 27(3):315–321

    Article  CAS  Google Scholar 

  • Elmi AS (1983) The chewing of khat in Somalia. J Ethnopharmacol 8(2):163–176

    Article  CAS  PubMed  Google Scholar 

  • EMCDDA (2012) Annual report 2012: the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon

    Google Scholar 

  • Gatter P (2012) Politics of Qat: the role of a drug in ruling Yemen. Jemen-Studien, vol Bd 20 1. Reichert, Wiesbaden

    Google Scholar 

  • Griffiths P, Lopez D, Sedefov R, Gallegos A, Hughes B, Noor A, Royuela L (2010) Khat use and monitoring drug use in Europe: the current situation and issues for the future. J Ethnopharmacol 132(3):578–583

    Article  PubMed  Google Scholar 

  • Halbach H (1972) Medical aspects of the chewing of khat leaves. Bull World Health Organ 47(1):21–29

    CAS  PubMed Central  PubMed  Google Scholar 

  • Hansen P (2010) The ambiguity of khat in Somaliland. J Ethnopharmacol 132:590–599

    Article  PubMed  Google Scholar 

  • Hoffman R, al’Absi M (2010) Khat use and neurobehavioral functions: suggestions for future studies. J Ethnopharmacol 132(3):554–563

    Article  PubMed Central  PubMed  Google Scholar 

  • Hoffman R, al’Absi M (2012) Working memory and speed of information processing in chronic khat users: preliminary findings. Eur Addict Res 19(1):1–6

    Article  PubMed  Google Scholar 

  • Kalix P (1990) Pharmacological properties of the stimulant khat. Pharmacol Ther 48(3):397–416

    Article  CAS  PubMed  Google Scholar 

  • Kalix P (1991) The pharmacology of psychoactive alkaloids from ephedra and catha. J Ethnopharmacol 32(1–3):201–208

    Article  CAS  PubMed  Google Scholar 

  • Kassim S, Croucher R (2006) Khat chewing amongst UK resident male Yemeni adults: an exploratory study. Int Dent J 56(2):97–101

    PubMed  Google Scholar 

  • Kassim S, Islam S, Croucher R (2010) Validity and reliability of a severity of dependence Scale for khat (SDS-khat). J Ethnopharmacol 132:570–577

    Article  PubMed  Google Scholar 

  • Kassim S, Islam S, Croucher RE (2011) Correlates of nicotine dependence in U.K. resident Yemeni khat chewers: a cross-sectional study. Nicotine Tob Res 13:1240

    Article  PubMed  Google Scholar 

  • Kassim S, Hawash A, Johnston A, Croucher R (2012) Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol 140(1):193–196

    Article  PubMed  Google Scholar 

  • Kebede D, Alem A, Mitike G, Enquselassie F, Berhane F, Abebe Y, Ayele R, Lemma W, Assefa T, Gebremichael T (2005) Khat and alcohol use and risky sex behaviour among in-school and out-of-school youth in Ethiopia. BMC Public Health 5:109

    Article  PubMed Central  PubMed  Google Scholar 

  • Kennedy JG, Teague J, Fairbanks L (1980) Qat use in North Yemen and the problem of addiction: a study in medical anthropology. Cult Med Psychiatry 4(4):311–344

    Article  CAS  PubMed  Google Scholar 

  • Khattab NY, Amer G (1995) Undetected neuropsychophysiological sequelae of khat chewing in standard aviation medical examination. Aviat Space Environ Med 66(8):739–744

    CAS  PubMed  Google Scholar 

  • Krikorian AD (1984) Kat and its use: an historical perspective. J Ethnopharmacol 12:115–178

    Article  CAS  PubMed  Google Scholar 

  • Kroll J, Yusuf AI, Fujiwara K (2011) Psychoses, PTSD, and depression in Somali refugees in Minnesota. Soc Psychiatry Psychiatr Epidemiol 46:481–493

    Article  PubMed  Google Scholar 

  • Mikulica J (2012) Cambridge gambling task, spatial span and tower of Hanoi performance among khat chewers. University of Konstant, Konstanz

    Google Scholar 

  • Nabuzoka D, Badhadhe FA (2000) Use and perception of khat among young Somalis in a UK city. Addict Res 8(1):5–26

    Article  Google Scholar 

  • Ndetei DM, Khasakhala LI, Ongecha-Owuor FA, Kuria MW, Mutiso V, Kokonya DA (2009) Prevalence of substance abuse among patients in general medical facilities in Kenya. Subst Abus 30(2):182–190

    Article  PubMed  Google Scholar 

  • Nencini P, Ahmed AM, Amiconi G, Elmi AS (1984) Tolerance develops to sympathetic effects of khat in humans. Pharmacology 28(3):150–154

    Article  CAS  PubMed  Google Scholar 

  • Nutt D, King LA, Saulsbury W, Blakemore C (2007) Development of a rational scale to assess the harm of drugs of potential misuse. Lancet 369(9566):1047–1053

    Article  PubMed  Google Scholar 

  • Odenwald M, Neuner F, Schauer M, Elbert TR, Catani C, Lingenfelder B, Hinkel H, Hafner H, Rockstroh B (2005) Khat use as risk factor for psychotic disorders: a cross-sectional and case-control study in Somalia. BMC Med 3(1):5

    Article  PubMed Central  PubMed  Google Scholar 

  • Odenwald M, Hinkel H, Schauer E, Neuner F, Schauer M, Elbert TR, Rockstroh B (2007) The consumption of khat and other drugs in Somali combatants: a cross-sectional study. PLoS Med 4(12):e341

    Article  PubMed Central  PubMed  Google Scholar 

  • Odenwald M, Hinkel H, Schauer E, Schauer M, Elbert T, Neuner F, Rockstroh B (2009) Use of khat and posttraumatic stress disorder as risk factors for psychotic symptoms: a study of Somali combatants. Soc Sci Med 69(7):1040–1048

    Article  PubMed  Google Scholar 

  • Odenwald M, Klein A, Warfa N (2010a) Introduction to the special issue: the changing use and misuse of khat (Catha edulis)–tradition, trade and tragedy. J Ethnopharmacol 132(3):537–539

    Article  PubMed  Google Scholar 

  • Odenwald M, Warfa N, Bhui K, Elbert T (2010b) The stimulant khat–another door in the wall? A call for overcoming the barriers. J Ethnopharmacol 132(3):615–619

    Article  PubMed  Google Scholar 

  • Odenwald M, Lingenfelder B, Peschel W, Haibe FA, Warsame AM, Omer A, Stockel J, Maedl A, Elbert T (2012) A pilot study on community-based outpatient treatment for patients with chronic psychotic disorders in Somalia: change in symptoms, functioning and co-morbid khat use. Int J Ment Heal Syst 6(1):8

    Article  Google Scholar 

  • Othieno CJ, Kathuku DM, Ndetei DM (2000) Substance abuse in outpatients attending rural and urban health centres in Kenya. East Afr Med J 77(11):592–595

    CAS  PubMed  Google Scholar 

  • Patel SL, Wright S, Gammampila A (2005) Khat use among Somalis in four English cities. vol Home Office Online Report 47/05. Home Office

    Google Scholar 

  • Teferra S, Hanlon C, Alem A, Jacobsson L, Shibre T (2011) Khat chewing in persons with severe mental illness in Ethiopia: a qualitative study exploring perspectives of patients and caregivers. Transcult Psychiatry 48(4):455–472

    Article  PubMed  Google Scholar 

  • Tulloch AD, Frayn E, Craig TK, Nicholson TR (2012) Khat use among Somali mental health service users in South London. Soc Psych Psych Epid 47(10):1649–1656

    Article  Google Scholar 

  • United Nations Office on Drugs and Crime (2012) World drug report 2012. United Nations, New York

    Google Scholar 

  • Warfa N, Klein A, Bhui K, Leavey G, Craig T, Stansfeld SA (2007) Khat use and mental illness: a critical review. Soc Sci Med 65:309–318

    Article  PubMed  Google Scholar 

  • Weir S (1985) Qat in Yemen: consumption and social change. British Museum Publications Limited, London

    Google Scholar 

  • Widmann M (2012) Trauma and psychotic symptoms among khat users – a pilot study with Somali refugees. University of Konstanz, Konstanz

    Google Scholar 

  • World Health Organization (2006) WHO Expert Committee on Drug Dependence, Thirty-fourth report. WHO Technical Report Series No. 942. WHO, Washington, DC

    Google Scholar 

Further Reading

  • Al-Habori M (2005) The potential adverse effects of habitual use of Catha edulis (khat). Expert Opin Drug Saf 4(6):1145–1154

    Article  PubMed  Google Scholar 

  • Griffiths P, Lopez D, Sedefov R, Gallegos A, Hughes B, Noor A, Royuela L (2010) Khat use and monitoring drug use in Europe: the current situation and issues for the future. J Ethnopharmacol 132(3):578–583

    Article  PubMed  Google Scholar 

  • Hoffman R, al’Absi M (2010) Khat use and neurobehavioral functions: suggestions for future studies. J Ethnopharmacol 132(3):554–563

    Article  PubMed Central  PubMed  Google Scholar 

  • Kassim S, Hawash A, Johnston A, Croucher R (2012) Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol 140(1):193–196

    Article  PubMed  Google Scholar 

  • Odenwald M, Warfa N, Bhui K, Elbert T (2010) The stimulant khat–another door in the wall? A call for overcoming the barriers. J Ethnopharmacol 132(3):615–619

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael Odenwald .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Italia

About this entry

Cite this entry

Odenwald, M., Klein, A., Warfa, N. (2015). Khat Addiction. In: el-Guebaly, N., Carrà, G., Galanter, M. (eds) Textbook of Addiction Treatment: International Perspectives. Springer, Milano. https://doi.org/10.1007/978-88-470-5322-9_19

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-5322-9_19

  • Published:

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5321-2

  • Online ISBN: 978-88-470-5322-9

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics