Abstract
Khat refers to the young and tender leaves and shoots of the khat tree (Catha edulis). It is an evergreen tree that can be found in the Abyssinian highlands, the Horn of Africa, Eastern and Southern Africa, the Arab peninsula, and Afghanistan. The alkaloid cathinone (S-(-)-a-aminopropiophenone) is considered to be the main psychoactive compound. The leaves and tender stems are usually chewed and kept in a tight wad in the cheek pocket. Within about 15–30 min, the user experiences physiological excitability, euphoria, talkativeness, and flow of ideas. Today, cathinone is listed in Schedule I and cathine in Schedule III of the international Convention on Psychotropic Substances of 1971, but the khat leaves are not internationally controlled. A problem with diagnosis of khat addiction is that established dependence criteria are not easily applicable as is the case for other traditional substances. More research information is needed about the prevalence of a khat dependence, its consequences, and its treatment.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
al’Absi M, Grabowski J (2012) Concurrent use of tobacco and khat: added burden on chronic disease epidemic. Addiction 107(2):451–452
Alemseged F, Haileamlak A, Tegegn A, Tessema F, Woldemichael K, Asefa M, Mamo Y, Tamiru S, Abebe G (2012) Risk factors for chronic non-communicable diseases at gilgel gibe field research center, southwest Ethiopia: population based study. Ethiop J Health Sci 22(S):19–28
Al-Habori M (2005) The potential adverse effects of habitual use of Catha edulis (khat). Expert Opin Drug Saf 4(6):1145–1154
Al-Motarreb A, Al-Habori M, Broadley KJ (2010) Khat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future research. J Ethnopharmacol 132:540–548
Anderson D, Beckerleg S, Hailu D, Klein A (2007) The Khat controversy: stimulating the debate on drugs. Berg, Oxford
Awas M, Kebede D, Alem A (1999) Major mental disorders in Butajira, southern Ethiopia. Acta Psychiatr Scand Suppl 397:56–64
Belew M, Kebede D, Kassaye M, Enquoselassie F (2000) The magnitude of khat use and its association with health, nutrition and socio-economic status. Ethiop Med J 38(1):11–26
Bhui K, Warfa N (2010) Trauma, khat and common psychotic symptoms among Somali immigrants: a quantitative study. J Ethnopharmacol 132:549–553
Bhui K, Abdi A, Abdi M, Pereira S, Dualeh M, Robertson D, Sathyamoorthy G, Ismail H (2003) Traumatic events, migration characteristics and psychiatric symptoms among Somali refugees–preliminary communication. Soc Psychiatry Psychiatr Epidemiol 38(1):35–43
Bimerew MS, Sonn FCT, Korlenbout WP (2007) Substance abuse and the risk of readmission of people with schizophrenia at Amanuel Psychiatric Hospital, Ethiopia. Curationis 30(2):74–81
Colzato LS, Ruiz M, Van den Wildenberg WP, Bajo M, Hommel B (2010) Long-term effects of chronic khat use: impaired inhibitory control. Front Psychol 1:129
Colzato LS, Ruiz MJ, van den Wildenberg WP, Hommel B (2011) Khat use is associated with impaired working memory and cognitive flexibility. PLoS One 6(6):e20602
Colzato LS, Ruiz MJ, van den Wildenberg WP, Hommel B (2012) Khat use is associated with increased response conflict in humans. Hum Psychopharm 27(3):315–321
Elmi AS (1983) The chewing of khat in Somalia. J Ethnopharmacol 8(2):163–176
EMCDDA (2012) Annual report 2012: the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon
Gatter P (2012) Politics of Qat: the role of a drug in ruling Yemen. Jemen-Studien, vol Bd 20 1. Reichert, Wiesbaden
Griffiths P, Lopez D, Sedefov R, Gallegos A, Hughes B, Noor A, Royuela L (2010) Khat use and monitoring drug use in Europe: the current situation and issues for the future. J Ethnopharmacol 132(3):578–583
Halbach H (1972) Medical aspects of the chewing of khat leaves. Bull World Health Organ 47(1):21–29
Hansen P (2010) The ambiguity of khat in Somaliland. J Ethnopharmacol 132:590–599
Hoffman R, al’Absi M (2010) Khat use and neurobehavioral functions: suggestions for future studies. J Ethnopharmacol 132(3):554–563
Hoffman R, al’Absi M (2012) Working memory and speed of information processing in chronic khat users: preliminary findings. Eur Addict Res 19(1):1–6
Kalix P (1990) Pharmacological properties of the stimulant khat. Pharmacol Ther 48(3):397–416
Kalix P (1991) The pharmacology of psychoactive alkaloids from ephedra and catha. J Ethnopharmacol 32(1–3):201–208
Kassim S, Croucher R (2006) Khat chewing amongst UK resident male Yemeni adults: an exploratory study. Int Dent J 56(2):97–101
Kassim S, Islam S, Croucher R (2010) Validity and reliability of a severity of dependence Scale for khat (SDS-khat). J Ethnopharmacol 132:570–577
Kassim S, Islam S, Croucher RE (2011) Correlates of nicotine dependence in U.K. resident Yemeni khat chewers: a cross-sectional study. Nicotine Tob Res 13:1240
Kassim S, Hawash A, Johnston A, Croucher R (2012) Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol 140(1):193–196
Kebede D, Alem A, Mitike G, Enquselassie F, Berhane F, Abebe Y, Ayele R, Lemma W, Assefa T, Gebremichael T (2005) Khat and alcohol use and risky sex behaviour among in-school and out-of-school youth in Ethiopia. BMC Public Health 5:109
Kennedy JG, Teague J, Fairbanks L (1980) Qat use in North Yemen and the problem of addiction: a study in medical anthropology. Cult Med Psychiatry 4(4):311–344
Khattab NY, Amer G (1995) Undetected neuropsychophysiological sequelae of khat chewing in standard aviation medical examination. Aviat Space Environ Med 66(8):739–744
Krikorian AD (1984) Kat and its use: an historical perspective. J Ethnopharmacol 12:115–178
Kroll J, Yusuf AI, Fujiwara K (2011) Psychoses, PTSD, and depression in Somali refugees in Minnesota. Soc Psychiatry Psychiatr Epidemiol 46:481–493
Mikulica J (2012) Cambridge gambling task, spatial span and tower of Hanoi performance among khat chewers. University of Konstant, Konstanz
Nabuzoka D, Badhadhe FA (2000) Use and perception of khat among young Somalis in a UK city. Addict Res 8(1):5–26
Ndetei DM, Khasakhala LI, Ongecha-Owuor FA, Kuria MW, Mutiso V, Kokonya DA (2009) Prevalence of substance abuse among patients in general medical facilities in Kenya. Subst Abus 30(2):182–190
Nencini P, Ahmed AM, Amiconi G, Elmi AS (1984) Tolerance develops to sympathetic effects of khat in humans. Pharmacology 28(3):150–154
Nutt D, King LA, Saulsbury W, Blakemore C (2007) Development of a rational scale to assess the harm of drugs of potential misuse. Lancet 369(9566):1047–1053
Odenwald M, Neuner F, Schauer M, Elbert TR, Catani C, Lingenfelder B, Hinkel H, Hafner H, Rockstroh B (2005) Khat use as risk factor for psychotic disorders: a cross-sectional and case-control study in Somalia. BMC Med 3(1):5
Odenwald M, Hinkel H, Schauer E, Neuner F, Schauer M, Elbert TR, Rockstroh B (2007) The consumption of khat and other drugs in Somali combatants: a cross-sectional study. PLoS Med 4(12):e341
Odenwald M, Hinkel H, Schauer E, Schauer M, Elbert T, Neuner F, Rockstroh B (2009) Use of khat and posttraumatic stress disorder as risk factors for psychotic symptoms: a study of Somali combatants. Soc Sci Med 69(7):1040–1048
Odenwald M, Klein A, Warfa N (2010a) Introduction to the special issue: the changing use and misuse of khat (Catha edulis)–tradition, trade and tragedy. J Ethnopharmacol 132(3):537–539
Odenwald M, Warfa N, Bhui K, Elbert T (2010b) The stimulant khat–another door in the wall? A call for overcoming the barriers. J Ethnopharmacol 132(3):615–619
Odenwald M, Lingenfelder B, Peschel W, Haibe FA, Warsame AM, Omer A, Stockel J, Maedl A, Elbert T (2012) A pilot study on community-based outpatient treatment for patients with chronic psychotic disorders in Somalia: change in symptoms, functioning and co-morbid khat use. Int J Ment Heal Syst 6(1):8
Othieno CJ, Kathuku DM, Ndetei DM (2000) Substance abuse in outpatients attending rural and urban health centres in Kenya. East Afr Med J 77(11):592–595
Patel SL, Wright S, Gammampila A (2005) Khat use among Somalis in four English cities. vol Home Office Online Report 47/05. Home Office
Teferra S, Hanlon C, Alem A, Jacobsson L, Shibre T (2011) Khat chewing in persons with severe mental illness in Ethiopia: a qualitative study exploring perspectives of patients and caregivers. Transcult Psychiatry 48(4):455–472
Tulloch AD, Frayn E, Craig TK, Nicholson TR (2012) Khat use among Somali mental health service users in South London. Soc Psych Psych Epid 47(10):1649–1656
United Nations Office on Drugs and Crime (2012) World drug report 2012. United Nations, New York
Warfa N, Klein A, Bhui K, Leavey G, Craig T, Stansfeld SA (2007) Khat use and mental illness: a critical review. Soc Sci Med 65:309–318
Weir S (1985) Qat in Yemen: consumption and social change. British Museum Publications Limited, London
Widmann M (2012) Trauma and psychotic symptoms among khat users – a pilot study with Somali refugees. University of Konstanz, Konstanz
World Health Organization (2006) WHO Expert Committee on Drug Dependence, Thirty-fourth report. WHO Technical Report Series No. 942. WHO, Washington, DC
Further Reading
Al-Habori M (2005) The potential adverse effects of habitual use of Catha edulis (khat). Expert Opin Drug Saf 4(6):1145–1154
Griffiths P, Lopez D, Sedefov R, Gallegos A, Hughes B, Noor A, Royuela L (2010) Khat use and monitoring drug use in Europe: the current situation and issues for the future. J Ethnopharmacol 132(3):578–583
Hoffman R, al’Absi M (2010) Khat use and neurobehavioral functions: suggestions for future studies. J Ethnopharmacol 132(3):554–563
Kassim S, Hawash A, Johnston A, Croucher R (2012) Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol 140(1):193–196
Odenwald M, Warfa N, Bhui K, Elbert T (2010) The stimulant khat–another door in the wall? A call for overcoming the barriers. J Ethnopharmacol 132(3):615–619
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Italia
About this entry
Cite this entry
Odenwald, M., Klein, A., Warfa, N. (2015). Khat Addiction. In: el-Guebaly, N., Carrà, G., Galanter, M. (eds) Textbook of Addiction Treatment: International Perspectives. Springer, Milano. https://doi.org/10.1007/978-88-470-5322-9_19
Download citation
DOI: https://doi.org/10.1007/978-88-470-5322-9_19
Published:
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-5321-2
Online ISBN: 978-88-470-5322-9
eBook Packages: MedicineReference Module Medicine