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Nicotine and Tobacco

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Textbook of Addiction Treatment: International Perspectives

Abstract

Although rates of tobacco use and dependence have been reduced substantially over the past 40 years, one in five Americans continues to smoke. The prevalence of smoking appears to be substantially higher in persons with psychiatric and substance use disorders and has remained unchanged, as these smokers have less success in quitting smoking. The epidemiology of tobacco use and dependence and the pharmacological effects of nicotine and tobacco are reviewed followed by a discussion of the clinical assessment of tobacco users. We then review behavioral and pharmacological treatments, including the FDA-approved pharmacotherapies: nicotine replacement therapies (NRTs), sustained-release bupropion, and varenicline. Finally, integration of tobacco dependence treatment into mental health settings is discussed with the view that tobacco dependence is a chronic medical disorder and that more effective treatment of this comorbidity in psychiatric disorders may require targeted treatments based on a better understanding of the pathophysiology of individual psychiatric disorders.

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Mackowick, K.M., George, T.P. (2015). Nicotine and Tobacco. In: el-Guebaly, N., Carrà, G., Galanter, M. (eds) Textbook of Addiction Treatment: International Perspectives. Springer, Milano. https://doi.org/10.1007/978-88-470-5322-9_17

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