Sympathetic ophthalmia is a potentially sight-threatening condition characterized by bilateral inflammation of the entire uveal tract that follows a perforating wound or surgical insult to one eye and has an insidious or acute onset and progressive course with recurrences. The clinical presentation is variable with some patients showing only posterior segment manifestations at initial presentation. Yellowish-white sub-RPE nodular lesions corresponding to histopathologic Dalen-Fuchs nodules are typical although not pathognomic of this condition. Long-term treatment with corticosteroids and immunomodulatory drugs is the mainstay of therapy.
KeywordsMycophenolate Mofetil Sympathetic Ophthalmia Multifocal Choroiditis Pigment Epitheliopathy Uveal Effusion
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