Multiple Evanescent White Dot Syndrome

Living reference work entry


Multiple evanescent white dot syndrome (MEWDS) is an inflammatory condition of the eye, unilateral in most of the cases, and generally characterized by a good visual prognosis with no need for treatment. MEWDS derives its name from its appearance at funduscopic examination that typically reveals multiple, yellow-white dots deep in the retina. Although an immune-mediated mechanism in a genetically susceptible person, triggered by a viral systemic infection, has been proposed as cause of MEWDS, Its precise pathogenesis remains unknown. There are no specific blood tests to diagnose MEWDS, however the disease shows peculiar findings on fundus autofluorescence and indocyanine green angiography. Thus, a multimodal imaging study with particular focus on these techniques is helpful in reaching the correct diagnosis avoiding useless treatments.


Fluorescein Angiography Well Correct Visual Acuity Spectral Domain Optical Coherence Tomography Indocyanine Green Angiography Outer Retinal Layer 

Suggested Reading

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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Uveitis and Ocular Infectious Diseases Service – Eye Clinic, Department of Biomedical and Clinical Science “Luigi Sacco”Luigi Sacco Hospital, University of MilanMilanItaly

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