Dengue Retinopathy

Living reference work entry


The fundus lesions seen in patients with dengue are often nonspecific and include retinal hemorrhages, peripapillary hemorrhages, Roth spots, cotton wool spots, intraretinal precipitates, retinal edema, neuroretinitis, vitreous hemorrhage, optic disk hyperemia, retinal vasculopathy, as well as dengue maculopathy. These retinal changes may occur in isolation or may be associated with anterior uveitis and vitritis.


Visual Acuity Optical Coherence Tomography Dengue Fever Cystoid Macular Edema Indocyanine Green Angiography 
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Suggested Reading

  1. Chan DP, Teoh SC, Tan CS, Nah GK, Rajagopalan R, Prabhakaragupta MK, Chee CK, Lim TH, Goh KY, Eye Institute Dengue-Related Ophthalmic Complications Workgroup. Ophthalmic complications of dengue. Emerg Infect Dis. 2006;12(2):285–9.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Chee E, Sims JL, Jap A, Tan BH, Oh H, Chee SP. Comparison of prevalence of dengue maculopathy during two epidemics with differing predominant serotypes. Am J Ophthalmol. 2009;148(6):910–3.CrossRefPubMedGoogle Scholar
  3. Kapoor HK, Bhai S, John M, Xavier J. Ocular manifestations of dengue fever in an East Indian epidemic. Can J Ophthalmol. 2006;41(6):741–6.CrossRefPubMedGoogle Scholar
  4. Lim WK, Mathur R, Koh A, Yeoh R, Chee SP. Ocular manifestations of dengue fever. Ophthalmology. 2004;111(11):2057–64.CrossRefPubMedGoogle Scholar
  5. Loh BK, Bacsal K, Chee SP, Cheng BC, Wong D. Foveolitis associated with dengue fever: a case series. Ophthalmologica. 2008;222(5):317–20.CrossRefPubMedGoogle Scholar
  6. Su DH, Bacsal K, Chee SP, Flores JV, Lim WK, Cheng BC, Jap AH, Dengue Maculopathy Study Group. Prevalence of dengue maculopathy in patients hospitalized for dengue fever. Ophthalmology. 2007;114(9):1743–7.CrossRefPubMedGoogle Scholar
  7. Teoh SC, Chee CK, Laude A, Goh KY, Barkham T, Ang BS, Eye Institute Dengue-related Ophthalmic Complications Workgroup. Optical coherence tomography patterns as predictors of visual outcome in dengue-related maculopathy. Retina. 2010;30(3):390–8.CrossRefPubMedGoogle Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  • Aliza Jap
    • 1
    • 2
  • Ranjana Mathur
    • 1
    • 3
    • 4
  • Soon-Phaik Chee
    • 1
    • 3
    • 4
    • 5
  1. 1.Singapore National Eye CentreSingaporeSingapore
  2. 2.Division of OphthalmologyChangi General HospitalSingaporeSingapore
  3. 3.Duke-NUS Graduate Medical SchoolSingaporeSingapore
  4. 4.Singapore Eye Research InstituteSingaporeSingapore
  5. 5.Department of OphthalmologyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore

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